Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Liprin-alpha
Flybase description The gene Liprin-α is referred to in FlyBase by the symbol Dmel\Liprin-α (CG11199, FBgn0046704).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.2104 -3.6701 -4.372213 -5.1723 -8.162442 -7.3002 -11.72794 -7.353382
    Affimetrix absolute value 4.81 5.764 6.066 6.032 5.743 5.702 5.06 5.419
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: R7 cell development; synapse assembly; regulation of axon extension involved in axon guidance; axon guidance; axon extension involved in development; anterograde synaptic vesicle transport; synaptic growth at neuromuscular junction; retinal ganglion cell axon guidance; axon target recognition; photoreceptor cell morphogenesis.
25 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor cell R7; medulla; bouton; neuromuscular junction; synaptic vesicle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Sterile alpha motif domain; Sterile alpha motif homology; Sterile alpha motif, type 1; Sterile alpha motif, type 2; Sterile alpha motif-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.
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