Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Brca2
Flybase description The gene Breast cancer 2, early onset homolog is referred to in FlyBase by the symbol Dmel\Brca2 (CG30169, FBgn0050169).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.1438 -6.9929 -16.044759 -10.776 -24.780971 -11.3977 -10.85151 -17.237232
    Affimetrix absolute value 4.828 4.816 4.276 4.991 4.177 5.072 5.136 4.243
    Affymetric present call in "x" number of chips 3 3 3 3 2 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: response to DNA damage stimulus; meiotic recombination checkpoint; double-strand break repair via homologous recombination.
7 alleles are reported.
The phenotypes of these alleles are annotated with: karyosome; dorsal appendage.
It has one annotated transcript and one annotated polypeptide.
Protein features are: BRCA2 repeat.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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