Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name LpR2
Flybase description The gene Lipophorin receptor 2 is referred to in FlyBase by the symbol Dmel\LpR2 (CG31092, FBgn0051092).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -21.369 -3.9195 -6.455009 -2.0184 -13.727863 -8.8291 -11.74603 -7.50074
    Affimetrix absolute value 4.039 5.66 5.49 7.409 4.994 5.42 5.142 5.419
    Affymetric present call in "x" number of chips 2 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: low-density lipoprotein receptor activity.
The biological processes in which it is involved are not known.
48 alleles are reported.
The phenotype of these alleles is annotated with: lipid droplet.
It has 7 annotated transcripts and 7 annotated polypeptides.
Protein features are: EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like region, conserved site; EGF-type aspartate/asparagine hydroxylation site; Epidermal growth factor-like; Epidermal growth factor-like, type 3; LDLR class B repeat; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Six-bladed beta-propeller, TolB-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.
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