Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name pb
Flybase description The gene proboscipedia is referred to in FlyBase by the symbol Dmel\pb (CG31481, FBgn0051481).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -54.346 -37.4866 -52.264466 -55.0563 -70.747695 -66.2204 -68.24728 -56.276838
    Affimetrix absolute value 2.658 2.41 2.489 2.62 2.626 2.513 2.461 2.465
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: specification of segmental identity, labial segment; proboscis development; specification of segmental identity, maxillary segment.
87 alleles are reported.
The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: organ system subdivision; adult segment; organ system; thoracic segment; appendage segment; external compound sense organ; integumentary specialisation; extended germ band embryo; imaginal precursor; non-connected developing system.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Homeobox; Homeobox protein, antennapedia type, conserved site; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression.
Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.
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