Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG31665
Flybase description The gene weary is referred to in FlyBase by the symbol Dmel\wry (CG31665, FBgn0051665).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -57.7355 -29.5729 -41.188064 -46.9069 -57.386744 -52.7896 -58.23306 -44.642993
    Affimetrix absolute value 2.562 2.743 2.831 2.843 2.919 2.845 2.693 2.783
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Notch binding.
There is experimental evidence that it is involved in the biological process: heart process; Notch signaling pathway.
9 alleles are reported.
The phenotype of these alleles is annotated with: adult heart.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: EGF; EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like region, conserved site; EGF-type aspartate/asparagine hydroxylation site; Epidermal growth factor-like; Epidermal growth factor-like, type 3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages.
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