Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fred
Flybase description The gene friend of echinoid is referred to in FlyBase by the symbol Dmel\fred (CG31774, FBgn0051774).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.2281 -25.8861 -34.007309 -37.4761 -47.754498 -48.0265 -51.7387 -28.329104
    Affimetrix absolute value 2.954 3.024 3.127 3.169 3.186 2.976 2.865 3.42
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: sensory organ development; adult chitin-based cuticle pattern formation; compound eye morphogenesis.
12 alleles are reported.
The phenotypes of these alleles are annotated with: eye; macrochaeta; adult cuticle; mesothoracic tergum; ommatidial precursor cluster; ommatidium; scutellum.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: CD80-like, immunoglobulin C2-set; Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.
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