Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name dro4
Flybase description The gene drosomycin-4 is referred to in FlyBase by the symbol Dmel\dro4 (CG32282, FBgn0052282).
Expression data along the gut
    Created with Highcharts 6.0.3Fold change compared to full gutRegion-specific expression of dro4 along the gutCropCardia/R1R2R3R4R5Hindgut-2-1012Highcharts.com
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.1948 -5.5274 -5.767372 -6.5191 -10.365713 -8.4095 -4.4604 -5.755383
    Affimetrix absolute value 5.871 5.181 5.691 5.702 5.414 5.502 6.448 5.744
    Affymetric present call in "x" number of chips 2 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Created with Highcharts 6.0.3Fold change compared toUnchallengedFold change compared to UnchallengedExpression of dro4 in different experimental conditionsEcc15 4hEcc15 16hPe 4hPe 16hPe gacA 4hPe gacA 16h-5051015Highcharts.com
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: defense response to fungus.
2 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Gamma thionin; Knottin.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of no expression detected.
Peak expression observed in adult male stages.
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