Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name NLaz
Flybase description The gene Neural Lazarillo is referred to in FlyBase by the symbol Dmel\NLaz (CG33126, FBgn0053126).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 5.0136 18.4853 1.116954 -4.8988 -7.976272 -4.0178 3.43599 1.91345
    Affimetrix absolute value 10.727 11.822 8.858 6.096 5.814 6.574 10.133 9.13
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: lipid binding.
There is experimental evidence that it is involved in the biological process: triglyceride homeostasis; determination of adult lifespan; response to oxidative stress; carbohydrate homeostasis.
6 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Calycin; Calycin-like; Invertebrate colouration protein; Lipocalin, ApoD type; Lipocalin/cytosolic fatty-acid binding protein domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of no expression detected.
Peak expression observed during late larval stages, during early pupal stages, in adult female stages.
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