Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sav
Flybase description The gene salvador is referred to in FlyBase by the symbol Dmel\sav (CG33193, FBgn0053193).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.0334 -5.6867 -4.655091 -5.4638 -6.831331 -7.5419 -9.87563 -5.879743
    Affimetrix absolute value 5.817 5.131 5.965 5.948 6.005 5.692 5.303 5.688
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: biological regulation; sensory organ development; cell proliferation; renal tubule development; response to ionizing radiation; stem cell differentiation; stem cell proliferation; programmed cell death; negative regulation of biological process; regulation of apoptosis; regulation of neurogenesis; neuron differentiation; response to stimulus.
30 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor cell R8 of pale ommatidium; eye; trichogen cell; photoreceptor cell R8 of yellow ommatidium; mesothoracic tergum; wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: SARAH; WW/Rsp5/WWP.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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