Flygut: an atlas of the Drosophila adult midgut

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Gene name Mical
Flybase description The gene Molecule interacting with CasL is referred to in FlyBase by the symbol Dmel\Mical (CG33208, FBgn0053208).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.7556 -11.5367 -15.571259 -13.5569 -19.576434 -14.1724 -9.13557 -14.650443
    Affimetrix absolute value 4.739 4.116 4.281 4.686 4.503 4.737 5.389 4.385
    Affymetric present call in "x" number of chips 1 0 1 2 0 3 3 0
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: actin binding.
There is experimental evidence that it is involved in the biological process: axon guidance; dendrite morphogenesis; neuron remodeling; sarcomere organization.
29 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; organ system subdivision; peripheral nervous system; multicellular structure; organelle; cytoplasmic part; adult segment; non-connected developing system; eo support cell; intracellular non-membrane-bounded organelle.
It has 13 annotated transcripts and 13 annotated polypeptides.
Protein features are: Calponin homology domain; Domain of unknown function DUF3585; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Zinc finger, LIM-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed during early pupal stages.
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