Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Unc-89
Flybase description The gene Unc-89 is referred to in FlyBase by the symbol Dmel\Unc-89 (CG33519, FBgn0053519).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.5974 -8.0032 -17.448626 -13.7868 -25.8215 -11.611 -3.1528 -16.102784
    Affimetrix absolute value 7.78 4.667 4.083 4.618 4.082 5.026 6.917 4.351
    Affymetric present call in "x" number of chips 3 3 0 1 0 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: Rho guanyl-nucleotide exchange factor activity; ATP binding; protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: adult somatic muscle development; sarcomere organization.
8 alleles are reported.
The phenotypes of these alleles are annotated with: M band; indirect flight muscle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Dbl homology (DH) domain; Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Myosin light chain kinase-related; Pleckstrin homology-type; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase-like domain; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed during late pupal stages.
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