Flygut: an atlas of the Drosophila adult midgut

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Gene name upd3
Flybase description The gene unpaired 3 is referred to in FlyBase by the symbol Dmel\upd3 (CG33542, FBgn0053542).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.1135 -6.7292 -13.204279 -12.5803 -17.190942 -12.7906 -21.04223 -12.560041
    Affimetrix absolute value 4.173 4.99 4.485 4.772 4.691 5.017 4.16 4.657
    Affymetric present call in "x" number of chips 0 3 1 3 2 3 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: receptor binding.
There is experimental evidence that it is involved in the biological process: paracrine signaling; positive regulation of cell proliferation; positive regulation of JAK-STAT cascade.
13 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: multicellular structure; anatomical structure; abdominal segment; thoracic segment; organ system; embryonic thoracic segment; embryonic abdominal segment 1; external compound sense organ; late extended germ band embryo; posterior spiracle primordium; organ system subdivision; prothoracic segment; portion of tissue.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of extremely low expression.
Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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