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| Gene name | form3 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene formin 3 is referred to in FlyBase by the symbol Dmel\form3 (CG33556, FBgn0053556). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: actin binding. There is experimental evidence that it is involved in the biological process: branch fusion, open tracheal system. 24 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord commissure; ventral nerve cord; embryonic/larval dorsal trunk; presumptive embryonic/larval tracheal system; longitudinal connective; dorsal trunk primordium. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Actin-binding FH2; Actin-binding FH2/DRF autoregulatory; Armadillo-type fold; Diaphanous FH3; GTPase-binding/formin homology 3; Haemagglutinin, stalk. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages. . |