Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name CG33958
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG33958 (FBgn0053958).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -30.0206 -12.8268 -16.063363 -23.8534 -15.637456 -18.655 -34.64717 -16.381351
    Affimetrix absolute value 3.513 3.975 4.226 3.823 4.805 4.354 3.436 4.241
    Affymetric present call in "x" number of chips 0 0 1 0 2 1 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: receptor activity; guanylate cyclase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: cGMP biosynthetic process; intracellular signal transduction.
6 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site; Haem NO binding associated; Nitrate/nitrite sensing protein.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
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