Flygut: an atlas of the Drosophila adult midgut

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Gene name Pde11
Flybase description The gene Phosphodiesterase 11 is referred to in FlyBase by the symbol Dmel\Pde11 (CG34341, FBgn0085370).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.3875 -0.3194 -1.774249 -1.7568 -4.142478 -2.1716 0.52685 -2.635702
    Affimetrix absolute value 7.156 7.637 7.395 7.621 6.778 7.45 8.777 6.946
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-AMP phosphodiesterase activity.
There is experimental evidence that it is involved in the biological process: cAMP metabolic process; lateral inhibition; cGMP metabolic process.
16 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: 3'5'-cyclic nucleotide phosphodiesterase; 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain; 3'5'-cyclic nucleotide phosphodiesterase, conserved site; GAF; Metal-dependent phosphohydrolase, HD domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.
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