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Gene name | Epac | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Epac is referred to in FlyBase by the symbol Dmel\Epac (CG34392, FBgn0085421). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: cyclic nucleotide-dependent guanyl-nucleotide exchange factor activity; Rap guanyl-nucleotide exchange factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: regulation of protein phosphorylation; regulation of small GTPase mediated signal transduction. 8 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; DEP domain; Guanine-nucleotide dissociation stimulator CDC25; Ras guanine nucleotide exchange factor; Ras guanine nucleotide exchange factor, domain; Ras guanine-nucleotide exchange factor, conserved site; Ras-association; Ras-like guanine nucleotide exchange factor, N-terminal; RmlC-like jelly roll fold; Winged helix-turn-helix transcription repressor DNA-binding; cAMP/cGMP-dependent protein kinase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period. . |