Flygut: an atlas of the Drosophila adult midgut

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Gene name Nox
Flybase description The gene NADPH oxidase is referred to in FlyBase by the symbol Dmel\Nox (CG34399, FBgn0085428).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -40.2051 -1.6227 -30.416253 -23.7523 -41.264223 -29.6508 -38.61499 -21.786373
    Affimetrix absolute value 3.081 6.924 3.285 3.87 3.407 3.672 3.283 3.86
    Affymetric present call in "x" number of chips 0 3 0 1 0 1 0 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: calcium ion binding; oxidoreductase activity; iron ion binding; electron carrier activity; flavin adenine dinucleotide binding.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process.
7 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Calcium-binding EF-hand; EF-hand-like domain; FAD-binding 8; Ferric reductase, NAD binding; Flavoprotein transmembrane component; Recoverin.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 12-18 embryonic stages, during late pupal stages.
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