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Gene name | pan | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene pangolin is referred to in FlyBase by the symbol Dmel\pan (CG34403, FBgn0085432). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: kinase binding; sequence-specific DNA binding; repressing transcription factor binding. There is experimental evidence that it is involved in the biological process: regulation of Wnt receptor signaling pathway; regulation of stem cell proliferation; spiracle morphogenesis, open tracheal system; embryonic pattern specification; regulation of hemocyte differentiation; positive regulation of transcription, DNA-dependent; imaginal disc-derived wing morphogenesis; salivary gland morphogenesis. 44 alleles are reported. The phenotypes of these alleles are annotated with 43 unique terms, many of which group under: organ system; organ system subdivision; adult segment; non-connected developing system; thoracic segment; late extended germ band embryo; portion of tissue; external compound sense organ; imaginal precursor; acellular anatomical structure. It has 12 annotated transcripts and 12 annotated polypeptides. Protein features are: CTNNB1 binding, N-teminal; High mobility group, HMG1/HMG2; High mobility group, superfamily. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period. . |