Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name NaCP60E
Flybase description The gene Na channel protein 60E is referred to in FlyBase by the symbol Dmel\NaCP60E (CG34405, FBgn0085434).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -35.3516 -28.8895 -40.679665 -43.2898 -48.700062 -47.0483 -48.23196 -46.186605
    Affimetrix absolute value 3.298 2.775 2.858 2.963 3.176 3.013 2.98 2.724
    Affymetric present call in "x" number of chips 0 3 1 2 3 1 1 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: voltage-gated sodium channel activity.
There is experimental evidence that it is involved in the biological process: olfactory behavior.
33 alleles are reported.
No phenotypic data is available.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: IQ motif, EF-hand binding site; Ion transport; Sodium ion transport-associated; Voltage gated sodium channel, alpha subunit.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 06-12 and 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
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