Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Tab2
Flybase description The gene TAK1-associated binding protein 2 is referred to in FlyBase by the symbol Dmel\Tab2 (CG7417, FBgn0086358).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.7675 -0.4679 -1.677202 -1.5826 -2.769522 -2.7277 -3.1732 -2.148148
    Affimetrix absolute value 6.495 7.445 7.445 7.739 7.301 7.126 6.916 7.186
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: response to bacterium; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; lateral inhibition; dendrite morphogenesis; peptidoglycan recognition protein signaling pathway; positive regulation of protein import into nucleus, translocation.
54 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Ubiquitin system component Cue; Zinc finger, RanBP2-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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