Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name alph
Flybase description The gene alphabet is referred to in FlyBase by the symbol Dmel\alph (CG1906, FBgn0086361).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.5071 0.2894 -1.378136 -1.5194 -2.84057 -1.7469 -1.89944 -2.219386
    Affimetrix absolute value 6.626 7.566 7.731 7.785 7.3 7.763 7.654 7.159
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine phosphatase activity.
There is experimental evidence that it is involved in the biological process: positive regulation of R7 cell differentiation; mitotic cell cycle; negative regulation of Ras protein signal transduction; response to oxidative stress; negative regulation of MAP kinase activity; imaginal disc-derived wing morphogenesis; compound eye morphogenesis.
11 alleles are reported.
The phenotypes of these alleles are annotated with: eye; primary pigment cell; cone cell; wing; wing vein.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Protein phosphatase 2C; Protein phosphatase 2C, manganese/magnesium aspartate binding site; Protein phosphatase 2C-like; Protein serine/threonine phosphatase 2C, C-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
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