Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Alg-2
Flybase description The gene Apoptosis-linked gene-2 is referred to in FlyBase by the symbol Dmel\Alg-2 (CG40410, FBgn0086378).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -35.2146 -17.6809 -23.764951 -25.5154 -33.29691 -31.0945 -37.59631 -27.44396
    Affimetrix absolute value 3.277 3.475 3.615 3.72 3.737 3.605 3.33 3.467
    Affymetric present call in "x" number of chips 0 0 1 2 1 3 1 1
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: calcium ion binding.
There is experimental evidence that it is involved in the biological process: positive regulation of JNK cascade.
3 alleles are reported.
The phenotypes of these alleles are annotated with: eye; wing hair.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand; EF-hand-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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