Flygut: an atlas of the Drosophila adult midgut

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Gene name Mer
Flybase description The gene Merlin is referred to in FlyBase by the symbol Dmel\Mer (CG14228, FBgn0086384).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.1206 -4.717 -7.259428 -6.1379 -12.138856 -8.9546 -5.5665 -10.122971
    Affimetrix absolute value 5.387 5.409 5.358 5.817 5.16 5.436 6.091 4.977
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 23 unique biological process terms, many of which group under: biological regulation; cellular component organization or biogenesis; localization; sensory organ development; cell cycle; response to stimulus; regulation of developmental process; cell cycle process; compound eye morphogenesis; spermatid differentiation; endocytic recycling; regulation of cell proliferation; negative regulation of biological process; multicellular organism reproduction.
55 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; organ system subdivision; adult segment; thoracic segment; imaginal precursor; external compound sense organ; spermatozoon; elongation stage spermatid; epithelial furrow; oocyte nucleus; integumentary plate.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Band 4.
1 domain; Band 4.
1 family; Ezrin/radixin/moesin; Ezrin/radixin/moesin family; Ezrin/radixin/moesin, C-terminal; FERM central domain; FERM domain; FERM, C-terminal PH-like domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; Merlin; Moesin; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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