Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name vvl
Flybase description The gene ventral veins lacking is referred to in FlyBase by the symbol Dmel\vvl (CG10037, FBgn0086680).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -30.6139 -18.4811 -27.924022 -32.3686 -37.768284 -33.5324 -30.11825 -28.367758
    Affimetrix absolute value 3.493 3.423 3.418 3.38 3.534 3.495 3.658 3.444
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: DNA binding; sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: motor axon guidance; brain development; brain segmentation; peripheral nervous system development.
29 alleles are reported.
The phenotypes of these alleles are annotated with 37 unique terms, many of which group under: organ system subdivision; organ system; adult segment; larval abdominal segment; non-connected developing system; sensory cluster; portion of tissue; adult; peripheral nervous system; region of integument.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Lambda repressor-like, DNA-binding; POU; POU-specific; Transcription factor, homeobox/POU.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages.
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