Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name vari
Flybase description The gene varicose is referred to in FlyBase by the symbol Dmel\vari (CG9326, FBgn0250785).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.3361 -2.708 -5.662442 -5.5641 -12.429224 -7.0742 -0.30211 -4.719833
    Affimetrix absolute value 8.825 6.209 5.676 5.924 5.122 5.742 8.566 6.023
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: guanylate kinase activity.
There is experimental evidence that it is involved in the biological process: dorsal trunk growth, open tracheal system; regulation of tube size, open tracheal system; open tracheal system development; regulation of tube length, open tracheal system; septate junction assembly.
30 alleles are reported.
The phenotypes of these alleles are annotated with: interommatidial bristle; embryonic/larval dorsal trunk; septate junction; presumptive embryonic/larval tracheal system; embryonic/larval tracheal system; lateral trunk primordium; dorsal trunk primordium; embryonic/larval transverse connective; wing hair; ganglionic branch primordium.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Guanylate kinase; Guanylate kinase, conserved site; Guanylate kinase/L-type calcium channel; L27; L27, C-terminal; PDZ/DHR/GLGF; Src homology-3 domain; Variant SH3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 06-18 hour embryonic stages.
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