Flygut: an atlas of the Drosophila adult midgut

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Gene name beta-Spec
Flybase description The gene β Spectrin is referred to in FlyBase by the symbol Dmel\β-Spec (CG5870, FBgn0250788).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.5989 2.3408 1.795017 2.2032 -0.545878 0.591 1.82233 0.582146
    Affimetrix absolute value 7.732 8.842 8.972 9.511 8.514 8.855 9.377 8.518
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: phosphatidylinositol-4,5-bisphosphate binding; microtubule binding; ankyrin binding.
There is experimental evidence that it is involved in the biological process: negative regulation of microtubule depolymerization; neuromuscular synaptic transmission; regulation of synapse organization; long-term strengthening of neuromuscular junction; axon guidance; nervous system development; photoreceptor cell axon guidance; maintenance of presynaptic active zone structure; axonogenesis; axon midline choice point recognition.
31 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; anatomical structure; synapse; portion of tissue; peripheral nervous system; cytoplasmic part; cell part; cell projection part; sense organ; postsynaptic membrane; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Actinin-type, actin-binding, conserved site; Calponin homology domain; Pleckstrin homology domain; Pleckstrin homology-type; Spectrin repeat; Spectrin, beta subunit; Spectrin/alpha-actinin; Spectrin/pleckstrin-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-24 hour embryonic stages, during early larval stages.
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