Flygut: an atlas of the Drosophila adult midgut

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Gene name alpha-Spec
Flybase description The gene α Spectrin is referred to in FlyBase by the symbol Dmel\α-Spec (CG1977, FBgn0250789).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.3428 5.8891 3.832871 5.8248 1.970146 3.6071 3.01619 3.061366
    Affimetrix absolute value 8.832 10.171 10.039 10.888 9.66 10.379 10.104 9.762
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: actin binding; microtubule binding.
There is experimental evidence that it is involved in the biological process: negative regulation of microtubule depolymerization; central nervous system development; neuromuscular synaptic transmission; regulation of synapse organization; germarium-derived oocyte fate determination; long-term strengthening of neuromuscular junction; oocyte construction; maintenance of presynaptic active zone structure; germarium-derived female germ-line cyst formation; axon midline choice point recognition.
46 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; anatomical structure; synapse; cytoplasmic part; non-connected developing system; portion of tissue; epithelial cell; postsynaptic membrane.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand; EF-hand, Ca insensitive; EF-hand-like domain; Spectrin alpha chain, SH3 domain; Spectrin repeat; Spectrin/alpha-actinin; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-24 hour embryonic stages, during early larval stages.
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