Flygut: an atlas of the Drosophila adult midgut

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Gene name mnb
Flybase description The gene minibrain is referred to in FlyBase by the symbol Dmel\mnb (CG42273, FBgn0259168).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -24.0704 -15.4778 -20.782087 -21.7004 -26.573246 -23.296 -19.52415 -19.98014
    Affimetrix absolute value 3.837 3.678 3.824 3.953 4.063 4.023 4.264 3.928
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine/tyrosine kinase activity; protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: olfactory learning; circadian rhythm; nervous system development; visual behavior; brain development.
25 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; embryonic/larval brain.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages.
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