Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name alpha-Man-I
Flybase description The gene α Mannosidase I is referred to in FlyBase by the symbol Dmel\α-Man-I (CG42275, FBgn0259170).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -24.7971 -16.5606 -25.799091 -28.0972 -37.25754 -34.4854 -1.95669 -21.205533
    Affimetrix absolute value 3.826 3.598 3.515 3.584 3.552 3.456 7.591 3.864
    Affymetric present call in "x" number of chips 1 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity.
There is experimental evidence that it is involved in the biological process: response to anesthetic; determination of adult lifespan.
41 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; interommatidial bristle; peripheral nervous system; ommatidium.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: Glycoside hydrolase, family 47.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 12-18 hour embryonic stages.
.