Flygut: an atlas of the Drosophila adult midgut

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Gene name grh
Flybase description The gene grainy head is referred to in FlyBase by the symbol Dmel\grh (CG42311, FBgn0259211).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.8118 -15.1823 -50.355441 -51.3521 -62.319787 -52.8063 -7.06783 -40.565913
    Affimetrix absolute value 6.149 3.719 2.561 2.715 2.797 2.844 5.768 2.947
    Affymetric present call in "x" number of chips 3 3 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; DNA binding.
There is experimental evidence that it is involved in the biological process: regulation of cell shape; R3/R4 cell fate commitment; nervous system development; tracheal outgrowth, open tracheal system; regulation of cell proliferation; epithelial cell morphogenesis; open tracheal system development; regulation of tube length, open tracheal system; plasma membrane organization; chitin-based embryonic cuticle biosynthetic process.
72 alleles are reported.
The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: late extended germ band embryo; organ system; non-connected developing system; tracheal branch primordium; multicellular structure; larval abdominal segment; cephalopharyngeal skeleton; adult segment; acellular anatomical structure; extended germ band embryo.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: CP2 transcription factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.
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