Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name cno
Flybase description The gene canoe is referred to in FlyBase by the symbol Dmel\cno (CG42312, FBgn0259212).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.057 -2.2461 -7.473543 -4.967 -12.133992 -5.1601 -6.42353 -11.299593
    Affimetrix absolute value 4.956 6.465 5.322 6.086 5.257 6.209 5.898 4.813
    Affymetric present call in "x" number of chips 1 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: actin binding.
There is experimental evidence that it is involved in the biological process: embryonic morphogenesis; dorsal closure; regulation of JNK cascade; epidermis morphogenesis; compound eye development; ommatidial rotation.
54 alleles are reported.
The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; histaminergic neuron; organ system; extended germ band embryo; head mesoderm; cell part; adherens junction; acellular anatomical structure; rhabdomere; primary pigment cell; cell junction.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Dil domain; Dilute; Forkhead-associated (FHA) domain; PDZ/DHR/GLGF; Ras-association; SMAD/FHA domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
.