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Gene name | C3G | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene C3G is referred to in FlyBase by the symbol Dmel\C3G (CG42328, FBgn0259228). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: Ras guanyl-nucleotide exchange factor activity. There is experimental evidence that it is involved in the biological process: Ras protein signal transduction; somatic muscle development; sarcomere organization; muscle attachment; regulation of Rap GTPase activity. 15 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system subdivision; external compound sense organ; organ system; adult segment; thoracic segment; peripheral nervous system; cell part; embryonic/larval hypodermal muscle; pigment cell; rhabdomere; adult; imaginal precursor. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Guanine-nucleotide dissociation stimulator CDC25; Ras guanine nucleotide exchange factor; Ras guanine nucleotide exchange factor, domain; Ras guanine-nucleotide exchange factor, conserved site; Ras-like guanine nucleotide exchange factor, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages. . |