Flygut: an atlas of the Drosophila adult midgut

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Gene name Pka-R1
Flybase description The gene cAMP-dependent protein kinase R1 is referred to in FlyBase by the symbol Dmel\Pka-R1 (CG42341, FBgn0259243).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -46.759 -23.6955 -24.854311 -34.9986 -46.18011 -48.5843 -49.76342 -27.203155
    Affimetrix absolute value 2.869 3.069 3.62 3.263 3.231 2.966 2.915 3.533
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cAMP-dependent protein kinase regulator activity.
There is experimental evidence that it is involved in the biological process: olfactory learning; neuromuscular synaptic transmission; response to ethanol; oocyte microtubule cytoskeleton polarization; molting cycle, chitin-based cuticle; actin filament organization.
25 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: adult segment; adult; organ system subdivision; organ system; thoracic segment; multicellular structure; acellular anatomical structure; metathoracic metatarsus; synapse; adult cuticle.
It has 18 annotated transcripts and 18 annotated polypeptides.
Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; RmlC-like jelly roll fold; cAMP-dependent protein kinase regulatory subunit; cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta; cAMP/cGMP-dependent protein kinase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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