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Gene name | Pka-R1 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene cAMP-dependent protein kinase R1 is referred to in FlyBase by the symbol Dmel\Pka-R1 (CG42341, FBgn0259243). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: cAMP-dependent protein kinase regulator activity. There is experimental evidence that it is involved in the biological process: olfactory learning; neuromuscular synaptic transmission; response to ethanol; oocyte microtubule cytoskeleton polarization; molting cycle, chitin-based cuticle; actin filament organization. 25 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: adult segment; adult; organ system subdivision; organ system; thoracic segment; multicellular structure; acellular anatomical structure; metathoracic metatarsus; synapse; adult cuticle. It has 18 annotated transcripts and 18 annotated polypeptides. Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; RmlC-like jelly roll fold; cAMP-dependent protein kinase regulatory subunit; cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta; cAMP/cGMP-dependent protein kinase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. . |