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Gene name | crb | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene crumbs is referred to in FlyBase by the symbol Dmel\crb (CG6383, FBgn0259685). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein kinase C binding. There is experimental evidence for 25 unique biological process terms, many of which group under: cellular component organization or biogenesis; biological regulation; cellular process; establishment or maintenance of bipolar cell polarity; sensory organ development; cell junction organization; compound eye photoreceptor development; system development; positive regulation of cell proliferation; gland morphogenesis; embryonic development via the syncytial blastoderm; open tracheal system development; establishment or maintenance of polarity of follicular epithelium; multicellular organism reproduction. 93 alleles are reported. The phenotypes of these alleles are annotated with 35 unique terms, many of which group under: organ system subdivision; organ system; external compound sense organ; non-connected developing system; adult segment; adherens junction; peripheral nervous system; spiracle; embryonic hindgut; imaginal precursor; late extended germ band embryo. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Concanavalin A-like lectin/glucanase; Concanavalin A-like lectin/glucanase, subgroup; EGF; EGF calcium-binding; EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like region, conserved site; EGF-type aspartate/asparagine hydroxylation site; Epidermal growth factor-like; Epidermal growth factor-like, type 3; Laminin G domain; Laminin G, subdomain 1; Laminin G, subdomain 2. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. . |