Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Fs
Flybase description The gene Follistatin is referred to in FlyBase by the symbol Dmel\Fs (CG33466, FBgn0259878).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -22.6251 -25.3962 -37.688483 -45.5049 -64.63884 -47.5787 -18.9088 -39.429247
    Affimetrix absolute value 3.909 2.968 2.962 2.882 2.747 2.99 4.563 2.996
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: negative regulation of decapentaplegic receptor signaling pathway; positive regulation of activin receptor signaling pathway; negative regulation of activin receptor signaling pathway.
7 alleles are reported.
The phenotypes of these alleles are annotated with: pupa; air bubble; ISNb; wing; embryonic/larval optic lobe; anterior pupal spiracle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Follistatin-like, N-terminal; Protease inhibitor, Kazal-type; Proteinase inhibitor I1, Kazal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.
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