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Gene name | Nop60B | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Nucleolar protein at 60B is referred to in FlyBase by the symbol Dmel\Nop60B (CG3333, FBgn0259937). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: pseudouridylate synthase activity. There is experimental evidence that it is involved in the biological process: wing disc development; ribosome biogenesis; germ cell development; rRNA processing; pseudouridine synthesis; neurogenesis. 21 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; adult segment; organ system subdivision; multicellular structure; thoracic segment; sense organ; eo support cell; adult; imaginal precursor; portion of tissue. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Dyskerin-like; PUA-like domain; Pseudouridine synthase II; Pseudouridine synthase, catalytic domain; Pseudouridine synthase-related; Pseudouridine synthase/archaeosine transglycosylase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages. . |