Flygut: an atlas of the Drosophila adult midgut

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Gene name kuz
Flybase description The gene kuzbanian is referred to in FlyBase by the symbol Dmel\kuz (CG7147, FBgn0259984).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -51.8179 -24.8342 -43.6682 -54.5011 -55.497901 -44.9064 -17.83838 -46.895888
    Affimetrix absolute value 2.761 3.02 2.732 2.623 3.005 3.086 4.552 2.708
    Affymetric present call in "x" number of chips 2 3 3 2 3 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: metalloendopeptidase activity.
There is experimental evidence that it is involved in the biological process: heart morphogenesis; Notch receptor processing; border follicle cell migration; glial cell migration; skeletal muscle tissue development; muscle tissue development; pericardial cell differentiation; cardiac cell differentiation; lymph gland development; phagocytosis, engulfment.
84 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system subdivision; organ system; adult segment; thoracic segment; external compound sense organ; sense organ; multicellular structure; peripheral nervous system; embryonic dorsal vessel; embryonic pericardial cell; non-connected developing system; imaginal precursor.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Blood coagulation inhibitor, Disintegrin; Metallopeptidase, catalytic domain; Peptidase M12B, ADAM/reprolysin; Peptidase M12B, propeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.
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