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Gene name | Dys | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Dystrophin is referred to in FlyBase by the symbol Dmel\Dys (CG34157, FBgn0260003). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: WW domain binding. There is experimental evidence that it is involved in the biological process: neuromuscular synaptic transmission; regulation of neurotransmitter secretion; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; regulation of short-term neuronal synaptic plasticity; muscle cell homeostasis; establishment of cell polarity. 52 alleles are reported. The phenotypes of these alleles are annotated with: posterior crossvein; t-bar; presynaptic active zone; oocyte; terminal button; neuromuscular junction; eye photoreceptor cell; indirect flight muscle. It has 8 annotated transcripts and 8 annotated polypeptides. Protein features are: Actinin-type, actin-binding, conserved site; Calponin homology domain; EF-hand domain, type 1; EF-hand domain, type 2; EF-hand-like domain; Spectrin repeat; Spectrin/alpha-actinin; WW/Rsp5/WWP; Zinc finger, ZZ-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages. . |