Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Su(var)3-3
Flybase description The gene Suppressor of variegation 3-3 is referred to in FlyBase by the symbol Dmel\Su(var)3-3 (CG17149, FBgn0260397).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -22.1944 -9.6436 -13.245258 -14.1546 -23.636345 -18.7711 -20.66127 -20.098768
    Affimetrix absolute value 3.94 4.355 4.475 4.585 4.233 4.337 4.201 4.016
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 2
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: oxidoreductase activity; flavin adenine dinucleotide binding.
There is experimental evidence that it is involved in the biological process: heterochromatin organization; chromatin organization; regulation of Notch signaling pathway; histone H3-K4 demethylation; imaginal disc-derived wing vein specification; oogenesis.
39 alleles are reported.
The phenotypes of these alleles are annotated with: ovariole; egg; female germline cell; follicle cell; wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Amine oxidase; Histone lysine-specific demethylase; Homeodomain-like; SWIRM; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.
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