Flygut: an atlas of the Drosophila adult midgut

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Gene name gwl
Flybase description The gene greatwall is referred to in FlyBase by the symbol Dmel\gwl (CG7719, FBgn0260399).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -50.3632 -31.3818 -44.376875 -49.8082 -56.771828 -40.0287 -54.11398 -46.288648
    Affimetrix absolute value 2.768 2.673 2.708 2.752 2.935 3.259 2.798 2.734
    Affymetric present call in "x" number of chips 0 0 0 0 0 1 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: regulation of meiosis; female meiosis I; regulation of mitotic centrosome separation; regulation of mitotic cell cycle; mitosis; regulation of mitosis; chromosome condensation.
24 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system subdivision; organ system; organelle; multicellular structure; intracellular non-membrane-bounded organelle; intracellular organelle part; cytoplasmic part; cell cycle; external compound sense organ; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: AGC-kinase, C-terminal; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.
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