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Gene name | Pp2A-29B | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Protein phosphatase 2A at 29B is referred to in FlyBase by the symbol Dmel\Pp2A-29B (CG17291, FBgn0260439). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine phosphatase activity; protein phosphatase type 2A regulator activity. There is experimental evidence that it is involved in the biological process: centrosome cycle; chromosome segregation; mitotic spindle organization; spindle assembly; neurogenesis; phagocytosis, engulfment. 7 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; neuroblast; mesothoracic tergum. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Armadillo-like helical; Armadillo-type fold; HEAT; HEAT, type 2. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, during early pupal stages, in adult female stages. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. . |