Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Gprk1
Flybase description The gene G protein-coupled receptor kinase 1 is referred to in FlyBase by the symbol Dmel\Gprk1 (CG40129, FBgn0260798).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.589 -0.6979 -2.160072 -1.8868 -3.58579 -2.3567 -1.92517 -2.609351
    Affimetrix absolute value 8.132 7.21 7.067 7.474 6.924 7.326 7.62 6.882
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: G-protein-coupled receptor binding; ATP binding; phosphatidylinositol binding; rhodopsin kinase activity.
There is experimental evidence that it is involved in the biological process: protein phosphorylation; imaginal disc-derived wing vein specification; phototransduction, visible light; metarhodopsin inactivation.
7 alleles are reported.
The phenotype of these alleles is annotated with: wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: AGC-kinase, C-terminal; GPCR kinase; Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Regulator of G protein signalling; Regulator of G protein signalling superfamily; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the pupal period.
.