Flygut: an atlas of the Drosophila adult midgut

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Gene name ird1
Flybase description The gene immune response deficient 1 is referred to in FlyBase by the symbol Dmel\ird1 (CG9746, FBgn0260935).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.9571 -4.2665 -6.84668 -6.763 -10.625992 -8.0203 -6.04708 -8.196863
    Affimetrix absolute value 5.247 5.528 5.437 5.658 5.42 5.571 5.961 5.237
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: cellular response to amino acid starvation; positive regulation of antibacterial peptide biosynthetic process; macroautophagy; regulation of antimicrobial peptide production.
14 alleles are reported.
The phenotype of these alleles is annotated with: melanotic mass.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Armadillo-like helical; Armadillo-type fold; G-protein beta WD-40 repeat; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
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