Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name RfC4
Flybase description The gene Replication factor C subunit 4 is referred to in FlyBase by the symbol Dmel\RfC4 (CG14999, FBgn0260985).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.1148 -6.2274 -11.783422 -7.6855 -10.404773 -5.6714 -6.87663 -9.616519
    Affimetrix absolute value 5.8 4.995 4.656 5.471 5.458 6.11 5.772 4.978
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATP-dependent DNA helicase activity.
There is experimental evidence that it is involved in the biological process: mitotic chromosome condensation; female meiosis chromosome segregation; DNA replication checkpoint; lateral inhibition; mitosis; DNA damage checkpoint; neurogenesis.
11 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; polytene chromosome; chaeta; polytene chromosome band; cell cycle; imaginal disc; embryonic/larval brain.
It has one annotated transcript and one annotated polypeptide.
Protein features are: ATPase, AAA+ type, core; ATPase, AAA-type, core; DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal; Replication factor C.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
.