Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Psa
Flybase description The gene Puromycin sensitive aminopeptidase is referred to in FlyBase by the symbol Dmel\Psa (CG1009, FBgn0261243).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.6939 1.3097 0.355997 0.2503 -1.548062 -0.4033 -3.47411 -1.492445
    Affimetrix absolute value 6.561 7.986 8.207 8.296 8.158 8.47 6.795 7.736
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: aminopeptidase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: proteolysis.
17 alleles are reported.
The phenotypes of these alleles are annotated with: eye; anterior crossvein; wing; ommatidium; wing hair; metatarsus.
It has 7 annotated transcripts and 7 annotated polypeptides.
Protein features are: Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase; Peptidase M1, membrane alanine aminopeptidase, N-terminal; Peptidase M1, puromycin-sensitive aminopeptidase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed during early pupal stages.
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