Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name CG42611
Flybase description The gene Megalin is referred to in FlyBase by the symbol Dmel\Megalin (CG42611, FBgn0261260).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.3939 -12.1363 -24.373412 -34.5938 -37.228241 -33.0679 -5.39278 -21.897779
    Affimetrix absolute value 5.352 4.05 3.585 3.279 3.547 3.521 6.146 3.808
    Affymetric present call in "x" number of chips 3 3 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: low-density lipoprotein receptor activity.
The biological processes in which it is involved are not known.
22 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: EGF calcium-binding; EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like region, conserved site; EGF-type aspartate/asparagine hydroxylation site; Epidermal growth factor-like; Epidermal growth factor-like, type 3; Growth factor, receptor; LDLR class B repeat; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Six-bladed beta-propeller, TolB-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages, during late pupal stages.
.