Flygut: an atlas of the Drosophila adult midgut

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Gene name Cul-3
Flybase description The gene Cullin-3 is referred to in FlyBase by the symbol Dmel\Cul-3 (CG42616, FBgn0261268).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.1881 -1.3586 -2.952257 -1.8289 -4.602607 -2.166 -1.9259 -4.102932
    Affimetrix absolute value 6.77 7.182 6.664 7.53 6.631 7.45 7.633 6.342
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: ubiquitin-protein ligase activity.
There is experimental evidence that it is involved in the biological process: activation of caspase activity; sensory organ development; dendrite morphogenesis; sperm individualization; imaginal disc-derived wing morphogenesis; axonogenesis; protein ubiquitination.
33 alleles are reported.
The phenotypes of these alleles are annotated with: sensillum campaniformium; wing margin bristle; anterior crossvein; wing vein L4; spermatid; wing hair.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Cullin homology; Cullin protein, neddylation domain; Cullin repeat-like-containing domain; Cullin, N-terminal; Cullin, conserved site; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed at stages throughout the pupal period, in adult male stages.
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