Flygut: an atlas of the Drosophila adult midgut

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Gene name Ppcs
Flybase description The gene Phosphopantothenoylcysteine synthetase is referred to in FlyBase by the symbol Dmel\Ppcs (CG5629, FBgn0261285).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.3079 -3.597 -4.28202 -3.8511 -8.820885 -5.0796 -8.99855 -6.502848
    Affimetrix absolute value 4.742 5.815 6.183 6.453 5.72 6.28 5.392 5.705
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: phosphopantothenate--cysteine ligase activity.
There is experimental evidence that it is involved in the biological process: bristle development; triglyceride homeostasis; actin cytoskeleton organization; germarium-derived female germ-line cyst encapsulation; ovarian follicle cell stalk formation; phospholipid homeostasis; cytoplasmic transport, nurse cell to oocyte; imaginal disc-derived wing morphogenesis; ovarian follicle cell migration; dorsal appendage formation.
19 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; portion of tissue; anatomical structure; adult; cytoplasmic part; external compound sense organ; adult segment; epithelial cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DNA/pantothenate metabolism flavoprotein, C-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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