Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression

Mean expression enrichment by gut region

Filter out everything which GO terms when the expression scale ratio is comprised between -1.5 and 1.5 for all regions
GO term Number of genes Crop
/ Full gut
R2
/ Full gut
R3
/ Full gut
R4
/ Full gut
R5
/ Full gut
Hindgut
/ Full gut
Cardia/R1
/ Full gut
exocyst 6 -1.08 1.29 1.41 1.24 1.37 1.05 1.07
M phase 379 1.18 1.09 1.2 1.09 1.24 1.18 1.08
protein deneddylation 3 1.57 -1.01 1.18 1.14 1.14 1.07 -1.1
cell morphogenesis 428 1.11 1.09 1.24 1.04 1.25 1.24 1.24
stress fiber 1 1.76 1.07 1.13 1.08 1.49 1.28 1.15
glycoprotein binding 1 3.21 -1.21 1.67 1.12 1.32 6.4 2.23
lymphocyte mediated immunity 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
renal sodium ion transport 1 -52.82 -1.7 -31.49 1.13 -9.63 16.55 -13.85
molecular_function 8833 1.01 -1.01 1.0 1.01 1.05 1.02 -1.0
ferrochelatase activity 1 1.62 1.26 1.09 -1.07 1.01 1.21 1.32
mesoderm development 91 1.26 -1.02 1.08 -1.05 1.17 1.32 1.03
RNA splicing 186 1.18 1.12 1.22 1.22 1.31 1.16 1.02
nicotinamidase activity 1 -2.04 1.72 -1.29 1.07 1.25 4.26 2.23
lipoate biosynthetic process 2 1.65 1.07 1.42 1.08 1.12 2.67 -1.13
FMN binding 10 1.36 1.09 1.23 1.12 -1.05 1.11 -1.08
response to UV-B 1 1.85 -1.14 1.04 1.61 1.1 1.04 1.04
ectodermal cell differentiation 2 4.98 -1.19 1.75 -1.46 1.16 1.31 1.35
vesicle membrane 23 -1.12 1.13 1.13 1.07 1.16 1.18 1.23
nuclear matrix 3 -1.0 1.28 1.38 1.16 1.24 1.52 1.32
ceramidase activity 2 -7.56 -2.15 -1.17 1.28 -1.14 -15.17 -6.93
acyl-CoA delta11-desaturase activity 1 -3.53 -3.34 -2.71 -4.29 -3.06 -2.31 4.71
peptidyl-serine modification 3 1.28 1.07 1.17 1.15 1.14 1.08 -1.08
cytokine binding 3 1.17 1.12 1.1 1.02 1.54 1.2 1.72
T-tubule 1 1.33 1.32 2.26 1.11 1.52 1.39 1.48
autosome 1 1.07 1.1 1.33 1.13 1.37 -1.12 1.05
A band 9 1.95 -1.09 -1.15 -1.11 1.13 1.79 1.07
cleavage furrow 9 -1.04 1.09 1.57 1.01 1.45 1.33 1.15
macromolecule localization 473 1.01 1.1 1.21 1.1 1.24 1.12 1.09
ESCRT-0 complex 2 -1.75 1.13 2.24 1.06 1.39 1.34 1.26
ribosome localization 1 2.15 -1.01 1.44 1.25 1.44 1.28 1.21
protein localization in Golgi apparatus 10 -1.16 1.12 1.17 1.04 1.21 1.41 1.65
pupation 4 2.01 -1.05 1.24 -1.24 1.14 2.15 1.25
DNA dealkylation 1 1.12 -1.01 1.19 1.74 1.2 1.06 -1.09
AP-2 adaptor complex binding 1 1.51 1.33 2.01 1.25 1.81 2.91 1.9
cargo receptor activity 36 1.1 -1.14 -1.08 -1.02 -1.03 1.05 -1.08
regulation of growth 153 1.13 1.15 1.39 1.07 1.32 1.3 1.24
DNA protection 1 1.02 -1.01 1.31 1.02 1.58 1.3 1.2
presynaptic membrane 8 -1.25 1.03 1.27 -1.02 1.34 1.8 1.18
fibril 1 1.02 -1.0 1.14 1.18 1.1 1.03 -1.08
DNA hypermethylation 3 1.11 1.01 1.05 1.05 1.09 1.06 -1.09
main axon 2 -1.07 -1.38 -1.02 -1.09 1.18 3.54 1.59
actin nucleation 4 -2.38 1.35 1.23 1.09 1.22 -1.94 1.21
negative regulation of S phase of mitotic cell cycle 11 1.34 1.21 1.41 1.15 1.44 1.65 1.53
imaginal disc fusion 16 1.01 1.24 1.46 1.12 1.3 1.23 1.22
female sex differentiation 19 1.28 1.1 1.09 1.01 1.21 1.14 1.12
protein autophosphorylation 7 -1.02 1.18 1.21 1.11 1.22 1.16 1.21
habituation 4 1.3 -1.01 1.62 1.18 1.4 1.83 1.26
eye pigmentation 34 1.13 -1.1 -1.23 1.11 1.01 -1.18 -1.07
chromosome localization 18 1.21 1.05 1.2 1.17 1.42 1.12 -1.0
localization 1626 -1.02 1.02 1.05 1.01 1.11 1.1 1.04
actin crosslink formation 1 2.2 1.13 -1.01 1.18 1.16 -1.08 1.17
glycolipid binding 1 -2.99 1.35 -1.24 1.41 -1.1 -2.55 -1.06
catecholamine transport 2 3.07 -1.44 -1.47 -1.28 -1.45 -1.2 -1.42
carboxylic ester hydrolase activity 99 -1.69 -1.12 -1.47 -1.07 -1.31 -2.03 -1.33
foraging behavior 1 -12.04 -1.69 9.34 -2.59 -11.09 -12.8 -6.11
regulation of canonical Wnt receptor signaling pathway 6 1.19 1.08 1.68 1.07 1.07 1.06 1.46
establishment of blood-brain barrier 19 2.5 -1.26 1.24 -1.17 1.21 2.3 1.4
neuroendocrine cell differentiation 2 -1.09 1.14 1.11 1.1 1.07 -1.24 1.07
Wnt protein secretion 1 1.86 -1.05 2.03 1.04 1.26 2.03 1.19
vitamin B6 binding 40 1.01 1.02 -1.27 -1.04 -1.03 -1.02 1.04
RISC-loading complex 1 1.44 1.23 1.89 1.19 2.25 1.64 1.56
cellular response to ecdysone 11 1.32 1.19 1.43 1.13 1.47 1.53 1.33
circulatory system development 70 1.28 -1.02 1.19 -1.07 1.17 1.3 1.17
regulation of ion homeostasis 3 1.14 1.14 1.39 1.16 1.04 1.71 1.47
mitochondrial genome maintenance 8 -1.05 1.17 1.44 1.18 1.23 1.21 -1.27
reproduction 846 1.12 1.06 1.15 1.03 1.18 1.14 1.14
ribosome biogenesis 52 1.28 1.16 1.24 1.3 1.29 1.06 1.05
protein binding involved in protein folding 2 1.49 1.24 1.02 1.11 1.08 1.24 1.18
unfolded protein binding 80 1.1 1.04 1.1 1.14 1.14 1.02 -1.05
protein thiol-disulfide exchange 1 -1.26 1.49 1.56 1.08 1.23 -1.31 1.33
disulfide oxidoreductase activity 30 1.14 1.05 -1.02 1.16 1.09 -1.11 -1.1
alpha-1,6-mannosyltransferase activity 1 1.2 1.3 1.28 1.05 1.27 1.14 1.6
trans-hexaprenyltranstransferase activity 2 2.38 1.18 1.12 1.03 1.43 1.86 1.15
single strand break repair 2 1.23 1.1 1.14 1.12 1.12 1.05 1.04
single-stranded DNA specific endodeoxyribonuclease activity 3 1.42 1.05 1.38 1.12 1.4 1.2 -1.23
phosphopyruvate hydratase complex 1 1.97 1.06 -1.39 -1.17 -1.32 2.59 1.17
alpha-glucoside transport 2 1.24 -2.16 -1.19 -2.0 -1.13 3.38 1.3
regulation of DNA recombination 2 -1.59 1.15 1.13 1.19 1.42 -1.74 -1.31
regulation of mitotic recombination 1 -2.02 1.1 1.06 1.2 1.9 -2.66 -1.77
negative regulation of mitotic recombination 1 -2.02 1.1 1.06 1.2 1.9 -2.66 -1.77
mitotic spindle elongation 72 1.4 1.08 1.2 1.04 1.24 1.24 1.15
alpha-1,2-mannosyltransferase activity 1 -1.58 1.15 -1.08 1.11 -1.2 -1.77 1.49
mannosyltransferase activity 12 -1.24 1.17 1.3 1.07 1.33 -1.21 1.12
acyl carrier activity 6 1.59 1.03 1.12 1.01 1.14 1.4 1.17
very long-chain fatty acid metabolic process 5 3.63 -2.39 -2.2 -3.1 -1.91 -1.08 3.71
long-chain fatty acid transporter activity 7 -2.15 1.3 -1.32 -1.52 -2.35 -1.39 -1.5
plasma membrane 575 1.16 1.01 1.11 -1.03 1.11 1.23 1.16
transition metal ion transport 17 1.11 1.0 1.11 -1.05 -1.09 1.21 1.05
protein targeting to Golgi 10 -1.16 1.12 1.17 1.04 1.21 1.41 1.65
autophagic vacuole assembly 2 1.21 1.14 -1.0 1.38 1.03 -1.03 -1.25
autophagic vacuole fusion 2 1.14 1.16 1.85 1.13 1.26 1.5 1.09
electron carrier activity 154 -1.07 -1.09 -1.18 -1.02 1.01 -1.08 -1.1
tRNA binding 9 1.2 1.27 1.24 1.22 1.15 1.15 1.01
urea cycle 1 -31.89 1.77 -20.72 1.41 1.0 -12.66 -3.5
argininosuccinate metabolic process 1 -31.89 1.77 -20.72 1.41 1.0 -12.66 -3.5
ribosomal subunit export from nucleus 1 2.15 -1.01 1.44 1.25 1.44 1.28 1.21
ribosomal large subunit export from nucleus 1 2.15 -1.01 1.44 1.25 1.44 1.28 1.21
protein import into nucleus, docking 2 -1.85 1.21 1.23 1.37 1.53 -1.37 -1.23
protein import into nucleus, translocation 2 1.98 -1.11 1.05 1.22 1.33 2.03 -1.05
fatty-acyl-CoA binding 8 -2.25 -1.27 -1.85 1.18 1.35 -2.52 -1.44
L-ornithine transmembrane transporter activity 1 1.32 1.45 -1.5 1.71 1.05 1.03 -1.1
mitochondrial ornithine transport 1 1.32 1.45 -1.5 1.71 1.05 1.03 -1.1
DNA replication 73 1.08 1.13 1.19 1.17 1.34 1.13 -1.02
chromosome segregation 124 1.15 1.1 1.25 1.11 1.3 1.2 1.1
chromosome organization 265 1.2 1.11 1.27 1.13 1.32 1.2 1.15
mitotic sister chromatid segregation 55 1.25 1.07 1.29 1.1 1.36 1.27 1.09
M phase specific microtubule process 1 1.59 1.65 -1.13 1.13 1.0 -1.46 -1.04
cell cycle checkpoint 84 1.23 1.14 1.35 1.19 1.41 1.29 1.15
DNA replication checkpoint 3 -1.03 -1.02 1.14 1.12 1.37 1.02 -1.1
DNA damage checkpoint 69 1.23 1.15 1.38 1.19 1.41 1.31 1.15
regulation of cyclin-dependent protein kinase activity 15 1.32 1.16 1.36 1.2 1.41 1.07 1.15
G1 phase of mitotic cell cycle 1 -1.2 1.72 1.55 1.31 1.53 1.21 1.72
G1/S transition of mitotic cell cycle 14 1.35 1.24 1.43 1.21 1.54 1.24 1.25
regulation of transcription involved in G1/S phase of mitotic cell cycle 1 1.31 1.43 1.45 1.16 1.14 1.54 1.46
S phase of mitotic cell cycle 3 -1.1 1.13 1.05 1.24 1.2 -1.11 -1.1
astral microtubule 4 -1.02 1.17 1.36 -1.01 1.32 1.27 1.24
G2 phase of mitotic cell cycle 1 1.67 1.26 1.32 1.4 1.23 1.13 1.21
G2/M transition of mitotic cell cycle 71 1.21 1.14 1.34 1.19 1.41 1.24 1.13
M phase of mitotic cell cycle 148 1.21 1.1 1.27 1.12 1.33 1.23 1.1
mitotic metaphase 1 -1.06 1.01 -1.03 1.11 -1.07 -1.08 -1.08
mitotic anaphase 19 1.3 1.13 1.29 1.17 1.36 1.32 1.11
mitotic anaphase A 4 -1.13 1.29 1.25 1.15 1.37 1.13 1.24
mitotic anaphase B 2 1.04 1.25 1.4 1.16 1.52 -1.16 1.12
mitotic telophase 1 1.4 1.02 1.15 1.14 1.72 -1.18 -1.16
sulfur amino acid metabolic process 11 1.06 -1.1 -1.32 1.02 -1.36 1.08 -1.14
sulfur amino acid biosynthetic process 3 1.32 1.11 1.04 -1.09 -1.92 1.19 1.3
sulfur amino acid catabolic process 1 1.48 1.28 1.32 1.05 1.07 1.16 -1.01
sulfur amino acid transmembrane transporter activity 1 -7.18 -1.45 -9.47 1.62 3.49 -2.41 -5.84
sulfur amino acid transport 1 -7.18 -1.45 -9.47 1.62 3.49 -2.41 -5.84
sulfate assimilation 1 -2.63 1.06 1.41 1.07 1.11 -1.64 -1.02
succinate dehydrogenase activity 6 1.02 1.03 1.28 -1.03 -1.0 1.38 -1.21
nucleotide-excision repair complex 3 1.73 1.2 1.21 1.15 1.32 1.1 -1.16
regulation of transcription involved in G2/M-phase of mitotic cell cycle 1 1.12 1.4 1.69 -1.0 1.67 1.7 1.71
histone deacetylase complex 16 1.3 1.16 1.3 1.17 1.34 1.37 1.21
negative regulation of transcription from RNA polymerase II promoter 104 1.12 1.05 1.08 -1.01 1.16 1.18 1.11
histone acetyltransferase complex 40 1.37 1.14 1.22 1.23 1.26 1.13 1.06
SAGA complex 20 1.38 1.1 1.14 1.26 1.22 1.03 -1.02
transcription factor TFIIIB complex 2 1.19 1.29 1.5 1.13 1.51 1.31 1.18
establishment of mitotic spindle orientation 2 1.02 1.4 1.82 1.21 1.49 1.4 1.34
Golgi cis cisterna 1 -1.12 1.19 1.36 1.12 1.23 -1.28 1.74
Golgi trans cisterna 2 -1.03 1.16 1.1 1.38 1.81 1.12 1.1
Golgi membrane 37 1.04 1.11 1.07 1.1 1.06 1.29 1.38
microfilament motor activity 3 6.28 -1.75 1.12 -1.66 1.09 3.74 -1.21
SNARE binding 6 -1.14 1.05 1.42 1.11 1.29 1.2 1.24
recombinase activity 4 1.15 1.04 -1.05 1.11 1.09 -1.16 -1.08
ubiquitin ligase complex 43 1.31 1.15 1.31 1.16 1.28 1.18 1.18
nuclear ubiquitin ligase complex 19 1.18 1.15 1.35 1.18 1.34 1.11 1.14
cytoplasmic ubiquitin ligase complex 1 2.69 1.18 1.72 1.15 -1.01 -1.18 -1.08
rRNA modification 5 1.57 1.18 1.26 1.33 1.41 1.18 -1.02
two-component sensor activity 3 1.12 -1.13 1.03 -1.08 1.69 1.52 -1.14
two-component response regulator activity 1 -1.1 1.39 1.36 1.05 1.38 3.53 1.68
protein phosphatase type 2A complex 8 1.09 1.04 1.37 1.07 1.23 2.15 1.1
two-component signal transduction system (phosphorelay) 3 -1.1 1.14 1.08 -1.02 -1.02 1.53 1.01
protein phosphatase type 1 complex 5 1.43 1.05 1.28 1.01 1.16 1.5 1.4
MAPK cascade 35 -1.01 1.14 1.46 1.09 1.46 1.19 1.31
nucleotide binding 1153 1.12 1.07 1.11 1.06 1.16 1.16 1.09
ribonuclease MRP complex 1 1.84 1.03 1.1 1.42 1.17 1.05 -1.14
3'-5'-exoribonuclease activity 15 1.46 1.13 1.16 1.27 1.25 1.2 1.04
nuclear exosome (RNase complex) 13 1.3 1.17 1.14 1.29 1.27 1.13 1.05
cytoplasmic exosome (RNase complex) 8 1.45 1.11 1.16 1.3 1.29 1.15 -1.0
exosome (RNase complex) 13 1.3 1.17 1.14 1.29 1.27 1.13 1.05
rRNA (adenine-N6,N6-)-dimethyltransferase activity 2 1.61 1.27 1.44 1.22 1.57 1.46 1.13
cytosolic large ribosomal subunit 50 1.38 1.02 1.09 1.0 1.14 1.2 1.09
cytosolic small ribosomal subunit 33 1.37 1.02 1.1 1.02 1.14 1.17 1.04
rDNA binding 2 -1.04 1.15 1.82 1.29 2.02 1.26 1.15
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 12 -1.19 1.17 1.13 1.22 1.25 -1.02 1.0
activation of MAPKKK activity 1 -1.25 1.21 1.4 1.19 1.07 1.11 1.44
activation of MAPKK activity 3 1.19 1.2 1.4 1.2 1.34 1.15 1.19
activation of MAPK activity 7 1.11 1.21 1.54 1.12 1.37 2.0 1.14
inactivation of MAPK activity 1 2.84 1.44 1.69 1.19 1.68 4.37 1.83
MAPK import into nucleus 1 1.14 1.19 1.6 1.04 1.48 1.45 1.57
protein binding 1244 1.17 1.05 1.21 1.04 1.22 1.2 1.14
modification-dependent protein catabolic process 94 1.17 1.13 1.33 1.13 1.3 1.1 1.12
protein ubiquitination involved in ubiquitin-dependent protein catabolic process 5 1.02 1.13 2.15 1.07 1.56 1.16 1.11
meiotic spindle organization 22 1.17 -1.06 -1.01 -1.07 1.19 1.02 1.17
tRNA-intron endonuclease activity 1 1.37 1.2 -1.07 1.24 1.11 -1.16 -1.02
tRNA-intron endonuclease complex 1 1.37 1.2 -1.07 1.24 1.11 -1.16 -1.02
DNA secondary structure binding 3 -1.08 1.33 1.37 1.18 1.48 -1.09 1.25
proton-transporting two-sector ATPase complex 48 -1.18 1.0 1.27 -1.11 -1.06 1.39 -1.15
vacuolar proton-transporting V-type ATPase, V0 domain 13 -2.32 -1.03 1.35 -1.29 -1.38 1.02 -1.29
vacuolar proton-transporting V-type ATPase, V1 domain 12 -1.17 1.02 1.44 -1.12 -1.04 1.8 -1.01
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity 1 -1.09 1.27 1.39 1.28 1.54 -1.1 1.18
microtubule cytoskeleton organization 338 1.13 1.1 1.24 1.09 1.26 1.18 1.09
nuclear chromosome 88 1.19 1.12 1.23 1.14 1.27 1.13 1.03
cytoplasmic chromosome 1 1.18 1.16 1.75 1.38 1.68 1.06 -1.24
condensed nuclear chromosome 15 1.25 1.06 1.23 1.06 1.25 1.24 1.09
condensed chromosome 38 1.15 1.06 1.23 1.09 1.3 1.2 1.07
mitotic prometaphase 1 -1.39 -1.16 -1.07 1.34 1.62 -1.16 -1.17
pericentriolar material 6 1.07 1.05 1.08 1.04 1.14 1.08 1.03
spliceosomal complex assembly 14 1.26 1.11 1.27 1.23 1.28 1.21 -1.02
C-4 methylsterol oxidase activity 2 -1.31 -6.89 -7.44 -1.07 -3.2 -1.65 -1.68
allantoin metabolic process 2 3.32 -1.45 -1.35 -1.39 -1.17 1.29 -1.34
allantoin catabolic process 1 2.85 -1.01 1.16 1.03 -1.08 1.74 -1.1
nitrilase activity 2 1.33 1.42 -1.12 1.25 1.47 1.28 -1.05
sodium:amino acid symporter activity 5 1.26 1.14 -2.06 -1.96 -1.76 -1.26 1.36
nucleoside transmembrane transporter activity 6 -1.51 1.3 -1.37 1.14 -1.09 -1.36 -1.05
intracellular 4036 1.14 1.07 1.15 1.08 1.18 1.16 1.05
proton-transporting ATPase activity, rotational mechanism 21 1.15 -1.01 1.22 -1.1 -1.03 1.64 -1.08
mitochondrial chromosome 1 1.18 1.16 1.75 1.38 1.68 1.06 -1.24
GTPase activity 136 1.2 1.08 1.29 1.07 1.22 1.09 1.05
heterotrimeric G-protein complex 18 1.39 1.11 1.42 1.06 1.22 1.03 1.1
mitochondrial fission 2 1.47 -1.03 1.65 1.15 1.07 1.58 -1.11
cell fraction 106 -1.02 -1.12 -1.21 -1.02 1.06 -1.09 -1.04
peroxisome targeting sequence binding 3 1.2 -1.04 -1.07 1.13 1.12 -1.21 -1.06
peptidoglycan metabolic process 12 -1.13 -1.64 -1.19 -1.04 -1.82 -1.69 -1.29
polysaccharide biosynthetic process 22 1.55 1.02 -1.01 1.03 1.12 1.58 1.25
polysaccharide catabolic process 30 -1.17 -1.91 -2.09 -1.67 -1.68 -1.04 1.4
mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) 8 1.58 -1.08 1.12 -1.1 1.01 1.92 -1.31
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) 9 1.19 1.04 1.31 1.01 1.22 1.62 -1.14
mitotic cell cycle 399 1.21 1.11 1.24 1.12 1.29 1.21 1.1
nuclear division 149 1.23 1.09 1.27 1.11 1.32 1.26 1.12
cytokinesis after mitosis 5 -1.12 1.17 1.26 1.17 1.24 -1.37 1.01
1-phosphatidylinositol-3-phosphate 5-kinase activity 1 -1.33 1.29 1.91 1.33 2.36 1.28 1.16
magnesium ion binding 46 1.08 1.06 1.18 1.05 1.15 1.38 1.01
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 10 1.48 1.17 1.74 1.19 1.61 1.9 1.56
nuclear-transcribed mRNA poly(A) tail shortening 7 1.62 1.13 1.74 1.15 1.59 2.05 1.42
deadenylation-dependent decapping of nuclear-transcribed mRNA 2 1.27 1.29 1.78 1.53 1.51 1.59 1.46
nuclear-transcribed mRNA catabolic process, exonucleolytic 1 -1.45 1.76 1.14 1.42 1.29 -1.3 1.32
integral to membrane of membrane fraction 2 1.74 1.04 1.6 1.07 1.43 2.77 1.46
peripheral to membrane of membrane fraction 2 -1.06 1.15 1.33 1.33 1.33 1.07 -1.07
retrograde transport, vesicle recycling within Golgi 10 -1.16 1.12 1.17 1.04 1.21 1.41 1.65
response to reactive oxygen species 16 1.05 1.06 1.08 1.15 1.2 -1.01 -1.15
response to superoxide 2 1.69 1.17 1.01 1.09 1.11 1.41 -1.08
response to oxygen radical 2 1.69 1.17 1.01 1.09 1.11 1.41 -1.08
cyclin-dependent protein kinase holoenzyme complex 7 1.06 1.09 1.22 1.21 1.41 -1.23 -1.12
nicotinamide-nucleotide adenylyltransferase activity 1 -2.52 1.99 1.32 1.32 1.09 -1.34 1.43
organellar ribosome 72 1.04 1.07 1.23 1.29 1.25 1.45 -1.55
organellar small ribosomal subunit 30 1.04 1.09 1.24 1.27 1.23 1.47 -1.48
organellar large ribosomal subunit 44 1.03 1.05 1.24 1.3 1.28 1.46 -1.6
protein-methionine-R-oxide reductase activity 1 2.04 1.02 -1.15 -1.19 -1.3 1.08 -1.25
lytic vacuole 28 -2.58 -1.1 -2.35 1.15 -1.08 -2.06 -3.03
negative regulation of transposition, DNA-mediated 1 -1.25 1.2 1.21 1.19 1.06 -1.14 1.03
regulation of transposition, DNA-mediated 1 -1.25 1.2 1.21 1.19 1.06 -1.14 1.03
RNA cap binding 13 1.12 1.12 1.2 1.04 1.14 1.12 1.32
RNA 7-methylguanosine cap binding 9 1.06 1.12 1.24 -1.0 1.11 1.11 1.44
THO complex 5 1.18 1.1 1.39 1.17 1.27 1.37 1.09
RNA splicing, via transesterification reactions 180 1.17 1.11 1.21 1.23 1.31 1.16 1.0
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 177 1.17 1.11 1.21 1.23 1.31 1.15 1.0
alternative nuclear mRNA splicing, via spliceosome 1 1.52 1.27 1.61 1.3 1.51 2.77 1.58
regulation of alternative nuclear mRNA splicing, via spliceosome 52 1.22 1.17 1.28 1.16 1.24 1.42 1.09
spliceosomal snRNP assembly 1 1.14 -1.01 1.12 1.41 1.03 -1.2 -1.43
spliceosomal complex disassembly 1 1.69 1.29 1.56 1.32 1.6 1.63 1.44
RNA splicing, via endonucleolytic cleavage and ligation 3 1.93 1.15 1.42 1.2 1.36 1.44 1.34
nuclear mRNA splicing, via spliceosome 177 1.17 1.11 1.21 1.23 1.31 1.15 1.0
four-way junction DNA binding 1 -1.12 1.35 2.36 1.33 2.9 1.28 1.43
Y-form DNA binding 1 1.11 1.31 -1.06 1.14 -1.02 -1.04 1.09
mitochondrion degradation 1 2.65 1.08 1.15 1.38 1.25 2.74 1.17
DNA-directed RNA polymerase complex 23 1.32 1.14 1.23 1.25 1.26 1.12 1.07
core TFIIH complex 4 1.37 1.09 1.37 1.35 1.33 1.15 1.06
SSL2-core TFIIH complex 4 1.37 1.09 1.37 1.35 1.33 1.15 1.06
maturation of 2S rRNA 1 1.7 -1.05 -1.07 -1.09 -1.18 1.33 1.14
base pairing 2 1.38 1.09 1.14 1.35 1.29 -1.02 -1.04
base pairing with RNA 2 1.38 1.09 1.14 1.35 1.29 -1.02 -1.04
proteasome complex 55 1.37 1.04 1.2 1.15 1.17 -1.02 1.02
embryonic axis specification 118 1.23 1.09 1.29 1.05 1.24 1.31 1.25
mismatch base pair DNA N-glycosylase activity 1 -1.08 1.06 -1.04 1.0 -1.17 1.06 -1.14
oxidized base lesion DNA N-glycosylase activity 3 2.16 -1.01 1.16 1.13 1.13 1.51 -1.03
oxidized pyrimidine base lesion DNA N-glycosylase activity 1 3.75 1.0 1.19 1.14 1.11 1.95 1.06
achiasmate meiosis I 1 -1.17 1.02 -1.13 1.11 -1.02 -1.2 -1.13
meiotic DNA recombinase assembly 1 -1.21 1.44 1.1 1.2 1.03 -1.18 1.17
meiotic mismatch repair 1 1.34 1.15 1.36 1.37 1.61 1.16 1.18
resolution of meiotic recombination intermediates 4 1.0 1.09 1.25 1.17 1.45 1.14 1.06
nucleotide-excision repair, DNA damage recognition 1 1.35 1.22 1.6 1.15 1.67 2.6 1.56
telomere maintenance 14 1.19 1.12 1.39 1.17 1.35 1.2 1.11
double-strand break repair via homologous recombination 7 1.12 1.16 1.16 1.17 1.22 -1.03 1.11
recombinational repair 7 1.12 1.16 1.16 1.17 1.22 -1.03 1.11
non-recombinational repair 6 -1.06 1.22 1.37 1.12 1.33 -1.11 1.14
DNA recombinase assembly 1 -1.21 1.44 1.1 1.2 1.03 -1.18 1.17
DNA synthesis involved in DNA repair 1 1.11 1.31 -1.06 1.14 -1.02 -1.04 1.09
strand displacement 1 1.11 1.31 -1.06 1.14 -1.02 -1.04 1.09
DNA catabolic process, endonucleolytic 4 1.64 1.12 1.39 1.15 1.35 1.4 1.54
DNA catabolic process, exonucleolytic 2 -1.31 1.21 1.11 1.22 1.62 -1.59 -1.29
DNA strand annealing activity 2 1.04 1.17 1.07 1.09 1.08 1.05 1.03
karyogamy 6 1.05 1.11 1.23 1.09 1.44 1.02 1.13
syncytium formation by plasma membrane fusion 27 1.01 1.06 1.27 -1.02 1.21 1.27 1.14
adenyl-nucleotide exchange factor activity 1 -1.14 1.21 -1.05 1.17 1.0 -1.29 -1.36
chromosome, centromeric region 54 1.2 1.07 1.19 1.11 1.31 1.15 1.07
kinetochore 31 1.18 1.08 1.16 1.14 1.33 1.13 -1.0
condensed chromosome kinetochore 9 1.03 1.06 1.14 1.12 1.28 -1.06 -1.03
condensed nuclear chromosome kinetochore 1 1.0 1.07 -1.07 1.19 -1.13 -1.28 1.01
condensed chromosome, centromeric region 13 1.09 1.06 1.24 1.12 1.37 1.11 1.02
condensed nuclear chromosome, centromeric region 7 1.24 1.07 1.34 1.12 1.41 1.38 1.12
chromosome, telomeric region 10 1.35 1.09 1.3 1.17 1.42 1.18 1.05
nuclear chromosome, telomeric region 2 1.89 1.01 1.39 1.11 1.79 1.05 1.11
chromatin 122 1.11 1.12 1.24 1.14 1.27 1.15 1.12
nucleosome 15 -1.1 1.01 1.25 1.15 1.09 -1.35 -1.01
nuclear nucleosome 1 1.0 1.07 -1.07 1.19 -1.13 -1.28 1.01
nuclear chromatin 49 1.15 1.15 1.25 1.15 1.27 1.14 1.09
euchromatin 12 1.14 1.22 1.34 1.18 1.46 1.33 1.26
heterochromatin 22 1.14 1.16 1.29 1.08 1.32 1.36 1.33
synaptonemal complex 4 1.04 1.05 1.03 1.0 -1.02 -1.06 1.06
condensin complex 8 1.13 1.05 1.18 1.06 1.26 1.27 1.12
sex chromosome 7 1.3 1.17 1.32 1.09 1.18 1.39 1.28
X chromosome 6 1.37 1.23 1.41 1.11 1.23 1.51 1.37
Y chromosome 1 -1.03 -1.14 -1.12 -1.01 -1.12 -1.2 -1.19
origin recognition complex 7 1.06 1.15 1.09 1.19 1.24 1.01 -1.08
GINS complex 2 1.77 1.11 1.3 1.14 1.18 1.14 -1.06
sister chromatid segregation 56 1.25 1.07 1.3 1.11 1.37 1.27 1.09
inositol-1,4,5-trisphosphate 6-kinase activity 1 -1.15 1.56 -1.07 1.07 -1.15 -1.25 1.09
inositol hexakisphosphate kinase activity 1 -1.38 1.16 2.02 -1.07 2.12 1.33 1.59
translation repressor activity, nucleic acid binding 6 1.94 1.04 2.03 1.04 1.61 1.46 1.82
cell morphogenesis involved in differentiation 351 1.14 1.09 1.26 1.04 1.28 1.28 1.26
cytokinesis 81 1.03 1.07 1.23 1.06 1.32 1.09 1.11
assembly of actomyosin apparatus involved in cell cycle cytokinesis 14 1.26 -1.24 -1.03 -1.27 1.08 1.13 1.08
cytokinesis, actomyosin contractile ring assembly 14 1.26 -1.24 -1.03 -1.27 1.08 1.13 1.08
contractile ring contraction involved in cell cycle cytokinesis 7 1.0 1.24 1.32 1.18 1.42 1.29 1.17
cytokinetic cell separation 1 -1.24 -1.05 1.11 1.18 1.4 -1.36 -1.18
spindle pole 23 1.28 1.12 1.43 1.06 1.39 1.41 1.26
gamma-tubulin complex 8 1.55 1.01 1.26 1.07 1.31 1.48 1.15
gamma-tubulin large complex 5 1.67 -1.04 1.23 1.09 1.31 1.41 1.1
cytoplasmic mRNA processing body 13 1.31 1.27 1.6 1.18 1.51 1.59 1.3
condensed chromosome inner kinetochore 1 1.0 1.07 -1.07 1.19 -1.13 -1.28 1.01
condensed chromosome outer kinetochore 7 -1.03 1.07 1.16 1.1 1.38 -1.08 -1.04
condensed nuclear chromosome inner kinetochore 1 1.0 1.07 -1.07 1.19 -1.13 -1.28 1.01
base pairing with rRNA 2 1.38 1.09 1.14 1.35 1.29 -1.02 -1.04
nuclear-transcribed mRNA catabolic process 23 1.11 1.16 1.34 1.18 1.37 1.32 1.21
mitochondrial RNA metabolic process 3 1.29 1.23 1.41 1.12 1.47 1.73 -1.1
regulatory region DNA binding 74 1.02 1.03 1.06 1.02 1.11 1.13 1.07
transcription regulatory region sequence-specific DNA binding 65 1.03 1.01 1.06 1.01 1.09 1.15 1.08
RNA polymerase II regulatory region sequence-specific DNA binding 45 1.09 -1.0 1.06 1.02 1.1 1.12 1.05
RNA polymerase II core promoter proximal region sequence-specific DNA binding 4 1.25 1.09 1.19 1.0 1.33 1.57 1.45
RNA polymerase II distal enhancer sequence-specific DNA binding 17 1.22 1.05 1.08 -1.03 1.01 1.06 1.21
sequence-specific DNA binding RNA polymerase II transcription factor activity 150 1.13 1.02 1.1 -1.01 1.12 1.15 1.16
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity 59 1.12 1.09 1.16 1.01 1.21 1.12 1.21
RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity 19 1.4 1.13 1.24 1.2 1.34 1.2 1.07
core promoter proximal region sequence-specific DNA binding 5 1.34 1.15 1.24 1.06 1.3 1.49 1.32
protein binding transcription factor activity 95 1.28 1.11 1.27 1.15 1.34 1.24 1.16
transcription factor binding transcription factor activity 95 1.28 1.11 1.27 1.15 1.34 1.24 1.16
RNA polymerase II regulatory region DNA binding 47 1.09 1.0 1.06 1.02 1.1 1.12 1.04
core promoter sequence-specific DNA binding 2 -1.01 1.32 1.26 1.21 1.46 1.11 1.06
core promoter binding 2 -1.01 1.32 1.26 1.21 1.46 1.11 1.06
regulatory region nucleic acid binding 74 1.02 1.03 1.06 1.02 1.11 1.13 1.07
nucleic acid binding transcription factor activity 411 1.09 1.04 1.09 1.01 1.1 1.11 1.09
sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly 18 1.41 1.13 1.25 1.21 1.36 1.2 1.08
RNA polymerase II transcription factor binding transcription factor activity 46 1.44 1.04 1.23 1.18 1.35 1.26 1.1
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription 40 1.12 1.13 1.2 1.01 1.21 1.17 1.23
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription 21 1.21 1.02 1.09 1.02 1.19 1.01 1.17
RNA polymerase II basal transcription factor binding transcription factor activity 6 1.58 1.1 1.46 1.16 1.41 1.29 1.2
RNA polymerase II transcription factor binding 15 1.46 -1.02 1.01 1.1 1.19 1.25 1.17
RNA polymerase II basal transcription factor binding 7 1.26 1.21 1.29 1.22 1.32 1.14 1.2
TFIIA-class transcription factor binding 3 1.34 1.29 1.39 1.2 1.61 1.37 1.28
TFIIB-class transcription factor binding 1 1.15 1.32 1.1 1.22 1.43 1.06 1.02
TFIID-class transcription factor binding 2 1.34 1.01 -1.02 1.28 1.04 -1.14 -1.12
TFIIF-class transcription factor binding 2 1.1 1.32 1.52 1.2 1.24 1.14 1.45
basal transcription machinery binding 8 1.09 1.07 1.15 1.14 1.23 1.02 1.08
basal RNA polymerase II transcription machinery binding 8 1.09 1.07 1.15 1.14 1.23 1.02 1.08
response to acid 5 1.44 -1.04 1.24 1.2 1.26 1.13 -1.15
RNA polymerase II activating transcription factor binding 4 2.11 -1.73 -1.85 -1.26 -1.03 1.44 1.34
RNA polymerase II repressing transcription factor binding 2 1.24 1.19 1.36 1.24 1.29 1.42 1.1
RNA polymerase II transcription cofactor activity 41 1.42 1.04 1.22 1.19 1.34 1.27 1.09
RNA polymerase II transcription coactivator activity 8 1.57 -1.19 -1.01 1.03 1.27 1.49 1.13
RNA polymerase II transcription corepressor activity 2 1.12 1.2 1.26 1.29 1.7 1.19 1.25
promoter clearance during DNA-dependent transcription 5 1.21 1.11 1.42 1.33 1.33 1.15 1.09
promoter clearance from RNA polymerase II promoter 5 1.21 1.11 1.42 1.33 1.33 1.15 1.09
DNA-dependent transcriptional open complex formation 5 1.21 1.11 1.42 1.33 1.33 1.15 1.09
transcriptional open complex formation at RNA polymerase II promoter 5 1.21 1.11 1.42 1.33 1.33 1.15 1.09
protein-DNA complex remodeling 5 1.21 1.11 1.42 1.33 1.33 1.15 1.09
RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly 2 1.66 -1.04 1.36 1.21 1.19 1.16 -1.0
TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly 6 1.58 1.1 1.46 1.16 1.41 1.29 1.2
TBP-class protein binding RNA polymerase II transcription factor activity 6 1.58 1.1 1.46 1.16 1.41 1.29 1.2
enhancer sequence-specific DNA binding 18 1.2 1.05 1.07 -1.02 1.0 1.04 1.19
core promoter proximal region DNA binding 5 1.34 1.15 1.24 1.06 1.3 1.49 1.32
DNA-dependent transcriptional start site selection 1 2.19 1.23 -1.08 1.33 1.17 -1.1 1.1
transcriptional start site selection at RNA polymerase II promoter 1 2.19 1.23 -1.08 1.33 1.17 -1.1 1.1
RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription 8 1.57 -1.19 -1.01 1.03 1.27 1.49 1.13
RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription 3 1.37 1.05 1.07 1.1 1.48 -1.12 1.13
age-dependent response to oxidative stress 1 -1.1 1.09 1.19 1.01 1.01 1.19 1.25
entry into host 2 1.04 1.05 1.19 -1.29 -1.39 2.64 1.17
neurotransmitter uptake 1 -1.06 -1.11 -1.0 -1.08 -1.15 3.37 -1.04
regulation of neurotransmitter levels 106 -1.07 1.06 1.19 1.11 1.22 1.06 1.07
neurotransmitter biosynthetic process 4 1.15 -1.01 -1.13 -1.06 1.01 -1.12 -1.05
acetylcholine catabolic process in synaptic cleft 1 2.27 1.23 -5.17 -1.59 -2.2 -9.9 9.42
regulation of action potential 8 1.57 -1.04 1.3 -1.12 1.17 2.65 1.29
cysteine-type endopeptidase activity 29 -1.39 -1.19 1.01 -1.08 1.27 -1.29 -1.2
RNA methylation 10 1.62 1.18 1.23 1.26 1.35 1.29 1.02
microfibril 1 1.02 -1.0 1.14 1.18 1.1 1.03 -1.08
calcium ion binding 192 1.36 -1.02 1.1 -1.05 1.09 1.28 1.2
selenocysteine incorporation 1 1.74 1.02 1.02 1.41 1.48 -1.49 -1.06
voltage-gated sodium channel complex 1 1.49 1.1 1.18 1.37 1.22 1.19 1.04
peptide amidation 1 2.74 1.3 1.75 1.08 1.98 1.97 2.28
pseudouridine synthesis 12 1.48 1.3 1.18 1.15 1.18 1.37 1.11
retinoid metabolic process 3 1.01 -1.01 1.02 1.05 -1.08 1.07 -1.1
oxygen transporter activity 11 1.36 1.04 1.04 -1.04 -1.15 1.01 -1.01
proteoglycan metabolic process 18 1.24 1.14 1.2 1.07 1.15 1.23 1.5
sulfur compound metabolic process 37 -1.0 1.04 1.02 1.1 1.02 1.18 1.06
lipopolysaccharide binding 1 8.83 -1.7 -1.73 -1.63 -1.34 3.89 1.3
ciliary or flagellar motility 2 1.0 -1.02 -1.01 -1.04 -1.08 -1.04 1.1
beta-amyloid binding 1 -1.11 1.12 -1.05 1.06 -1.09 -1.06 -1.01
ovarian follicle development 1 -1.49 2.58 -1.26 -1.23 -1.23 -1.38 1.24
oocyte growth 2 1.25 1.36 1.54 1.22 1.6 1.07 1.72
oocyte maturation 3 -1.0 1.13 -1.07 -1.01 -1.03 -1.0 1.1
metabolic process 3907 -1.04 -1.03 -1.04 1.02 1.06 -1.04 -1.05
cell growth 59 1.22 1.13 1.38 1.04 1.43 1.35 1.28
regulation of cell growth 38 1.09 1.19 1.46 1.1 1.43 1.53 1.25
heterophilic cell-cell adhesion 12 -1.44 1.04 1.3 -1.02 1.46 -1.24 1.32
galactoside binding 2 1.45 -1.07 1.88 1.03 1.06 1.31 1.14
microtubule bundle formation 16 -1.31 1.1 1.24 1.11 1.2 -1.29 -1.07
detection of chemical stimulus involved in sensory perception of bitter taste 1 -1.77 -1.51 -1.46 -1.66 9.03 1.38 -1.43
detection of chemical stimulus involved in sensory perception of sweet taste 1 15.43 1.05 -1.1 -1.34 2.06 11.73 3.15
Gi/o-coupled serotonin receptor activity 1 1.44 1.03 -1.0 1.12 1.06 1.16 -1.02
Gq/11-coupled serotonin receptor activity 1 1.13 -1.11 -1.04 -1.12 -1.18 1.14 1.05
dopamine receptor activity, coupled via Gs 2 -1.21 1.11 -1.21 1.0 -1.21 -1.22 -1.28
dopamine receptor activity, coupled via Gi/Go 1 -1.08 -1.06 -1.29 1.12 -1.04 -1.27 -1.07
neuromedin U receptor activity 1 -1.22 -1.11 -1.12 -1.18 -1.25 -1.3 -1.2
G-protein coupled adenosine receptor activity 1 -1.32 1.16 1.21 -1.14 -1.21 1.47 1.08
dense fibrillar component 1 -1.19 1.16 -1.05 1.68 1.27 -1.6 -1.28
peptide receptor activity 45 1.11 -1.06 1.03 -1.06 -1.05 1.15 1.01
eye development 265 1.14 1.1 1.26 1.06 1.27 1.23 1.24
urogenital system development 69 1.2 -1.03 1.12 -1.01 1.21 1.35 1.08
conditioned taste aversion 3 1.58 1.48 1.62 -1.13 1.26 1.28 1.57
G-protein coupled receptor binding 7 -1.1 -1.01 1.12 -1.08 1.17 1.16 1.2
response to hypoxia 43 1.14 1.14 1.22 1.08 1.27 1.28 1.2
ameboidal cell migration 35 1.62 -1.01 1.31 -1.06 1.21 1.46 1.11
acrosomal vesicle 1 -1.22 1.14 1.06 1.01 -1.52 -1.37 1.04
ATPase activator activity 3 1.77 1.07 1.2 1.24 1.37 1.32 1.35
regulation of chromatin assembly or disassembly 6 1.1 1.2 1.31 1.12 1.3 1.19 1.21
male germ cell nucleus 10 -1.1 1.13 1.01 1.03 -1.05 -1.24 1.05
female germ cell nucleus 1 1.04 1.22 1.16 1.15 1.04 -1.0 -1.09
long-chain fatty acid metabolic process 8 2.31 -2.32 -1.73 -1.98 -1.14 -1.49 1.69
formation of translation initiation ternary complex 1 1.02 1.21 1.26 1.24 1.31 1.17 1.22
tRNA 5'-leader removal 1 -1.05 1.03 -1.13 -1.0 -1.0 -1.23 -1.11
axonemal dynein complex 12 -1.02 1.03 1.04 1.02 -1.05 1.0 -1.11
cytoplasmic dynein complex 11 -1.01 1.07 1.14 1.01 1.06 1.15 -1.02
histamine metabolic process 2 1.02 -1.27 1.33 1.09 1.3 1.8 1.14
histamine biosynthetic process 1 -1.31 -1.76 1.72 1.22 1.97 3.11 1.28
embryonic development via the syncytial blastoderm 159 1.1 1.06 1.3 1.03 1.34 1.33 1.22
gastrulation with mouth forming first 30 1.11 -1.0 1.2 1.03 1.32 1.16 1.06
formation of primary germ layer 28 1.53 -1.01 1.18 -1.09 1.11 1.67 1.15
ectoderm formation 2 4.98 -1.19 1.75 -1.46 1.16 1.31 1.35
endoderm formation 4 2.13 -1.15 1.08 -1.19 1.07 2.11 1.76
mesoderm formation 26 1.41 1.01 1.15 -1.07 1.1 1.6 1.11
cell fate specification 59 1.11 1.06 1.1 1.04 1.17 -1.02 1.22
cell fate determination 122 1.2 1.07 1.23 1.02 1.24 1.19 1.2
mesodermal cell fate commitment 16 1.47 1.02 1.02 -1.04 1.04 1.32 1.13
endodermal cell fate commitment 1 8.12 -1.58 1.44 -1.54 1.01 1.69 1.21
ectodermal cell fate commitment 2 4.98 -1.19 1.75 -1.46 1.16 1.31 1.35
ectodermal cell fate specification 2 4.98 -1.19 1.75 -1.46 1.16 1.31 1.35
intermediate filament 2 1.28 1.06 -1.0 1.32 1.15 -1.17 -1.1
ruffle 2 1.28 1.39 2.24 -1.02 2.03 1.81 1.72
lipid kinase activity 2 1.57 1.08 1.68 -1.01 1.59 1.77 1.96
ceramide kinase activity 1 2.79 -1.02 1.66 -1.11 1.24 2.25 2.21
establishment of planar polarity 70 1.2 1.06 1.23 1.01 1.28 1.24 1.46
establishment of imaginal disc-derived wing hair orientation 22 1.56 1.08 1.28 1.02 1.4 1.32 1.3
morphogenesis of a polarized epithelium 79 1.19 1.08 1.28 1.02 1.3 1.27 1.44
oenocyte differentiation 8 1.23 1.09 1.12 1.12 1.24 1.37 1.16
optic placode formation 4 -1.14 1.1 1.23 1.12 1.47 -1.2 -1.08
optic lobe placode formation 4 -1.14 1.1 1.23 1.12 1.47 -1.2 -1.08
compound eye morphogenesis 198 1.16 1.1 1.25 1.06 1.25 1.2 1.26
Bolwig's organ morphogenesis 9 1.23 -1.01 1.15 1.06 1.23 1.18 1.03
optic lobe placode development 8 -1.18 1.11 1.22 1.1 1.34 -1.02 1.03
compound eye photoreceptor cell differentiation 117 1.22 1.11 1.3 1.08 1.29 1.25 1.2
compound eye photoreceptor fate commitment 51 1.32 1.09 1.23 1.09 1.32 1.24 1.18
compound eye photoreceptor development 60 1.11 1.12 1.33 1.04 1.24 1.21 1.22
eye photoreceptor cell differentiation 120 1.21 1.12 1.32 1.08 1.29 1.26 1.21
morphogenesis of a branching structure 48 1.11 1.11 1.43 1.03 1.35 1.27 1.3
neuron migration 1 -1.42 1.01 1.2 1.29 2.44 -1.59 1.35
cell activation 10 1.19 1.04 1.07 1.06 -1.05 1.15 1.06
phosphotyrosine binding 1 -1.42 1.22 1.22 1.19 1.41 -1.04 -1.04
kidney development 3 -1.1 -1.05 -1.04 -1.15 -1.04 1.01 1.54
epithelial to mesenchymal transition 1 1.47 1.13 -1.02 1.1 -1.07 -1.03 1.1
embryonic epithelial tube formation 6 1.03 -1.09 1.01 -1.18 -1.08 1.45 1.48
opsonin receptor activity 1 1.18 1.16 1.11 1.22 1.12 1.2 1.16
pattern binding 116 -1.88 -1.54 -1.66 -1.39 -1.53 -1.88 1.19
response to yeast 1 5.18 -1.34 1.33 -1.5 1.33 6.7 1.77
nucleoside binding 5 -2.97 1.34 -1.45 1.07 -1.17 -2.3 -1.24
endothelial cell development 3 1.7 1.01 1.41 -1.21 1.32 4.52 2.14
selenium compound metabolic process 2 1.76 1.25 1.23 1.04 1.04 1.62 -1.07
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity 1 1.03 1.3 1.31 1.09 1.28 -1.03 1.49
tissue homeostasis 20 1.33 -1.02 1.13 -1.12 1.22 1.46 1.54
retina homeostasis 2 -1.1 1.15 1.07 1.1 1.01 1.07 1.17
regulation of protein phosphorylation 65 1.23 1.16 1.37 1.12 1.3 1.37 1.18
negative regulation of protein phosphorylation 2 -1.04 1.11 1.79 -1.0 1.29 1.24 1.01
positive regulation of protein phosphorylation 5 1.08 1.17 1.78 1.11 1.35 1.9 1.34
regulation of cell-matrix adhesion 2 1.91 1.0 2.08 1.07 1.96 1.63 1.31
negative regulation of cell-matrix adhesion 1 2.96 1.13 1.75 -1.2 1.98 1.94 1.75
startle response 13 1.09 1.15 1.46 1.07 1.52 1.19 1.26
G-protein alpha-subunit binding 2 -1.16 1.18 -1.02 1.16 1.01 -1.6 -1.07
morphogenesis of an epithelium 238 1.18 1.05 1.28 1.02 1.3 1.33 1.27
morphogenesis of an epithelial sheet 1 1.57 1.36 1.53 1.09 1.59 1.28 1.35
regulation of heart rate 3 -2.33 1.98 1.4 -1.73 -1.39 2.29 -1.17
regulation of sodium ion transport 6 -1.09 1.11 1.21 1.02 1.05 -1.15 1.01
p53 binding 1 1.78 1.16 2.67 1.12 2.53 3.19 2.15
positive regulation of neuroblast proliferation 2 -1.35 1.28 1.19 1.29 1.21 -1.02 1.09
epithelial cell development 14 1.16 1.1 1.33 1.01 1.23 1.71 1.39
protein depalmitoylation 2 2.75 1.12 1.29 1.19 1.61 1.16 1.22
regulation of receptor internalization 2 2.64 -1.34 1.04 -1.28 -1.11 2.63 1.36
positive regulation of receptor internalization 2 2.64 -1.34 1.04 -1.28 -1.11 2.63 1.36
polyprenyltransferase activity 1 1.04 1.26 1.1 1.28 -1.02 -1.97 -1.12
tRNA wobble base modification 2 1.94 1.19 1.23 1.17 1.27 1.92 1.12
tRNA wobble uridine modification 2 1.94 1.19 1.23 1.17 1.27 1.92 1.12
podosome 1 -1.23 -1.76 -1.82 -1.76 -2.16 17.9 -1.88
store-operated calcium entry 1 2.66 -1.14 1.6 1.07 1.44 4.2 2.14
aggressive behavior 44 1.19 1.05 1.23 -1.02 1.15 1.61 1.24
inter-male aggressive behavior 42 1.18 1.06 1.2 1.0 1.15 1.58 1.25
G-quadruplex RNA binding 1 1.1 1.52 1.31 1.18 1.34 1.42 1.38
larval development 73 1.16 1.08 1.33 1.02 1.21 1.2 1.27
instar larval or pupal development 424 1.18 1.05 1.22 1.02 1.26 1.27 1.22
instar larval development 48 1.09 1.08 1.31 1.01 1.22 1.22 1.26
palmitoyltransferase complex 1 -1.92 1.11 2.34 1.27 1.64 -1.44 -1.26
defense response to insect 1 23.01 -3.14 -2.9 -3.17 -2.48 1.73 2.58
positive regulation of antimicrobial peptide production 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
innate immune response in mucosa 1 -1.37 -1.13 -1.19 -1.54 1.82 7.35 2.8
response to molecule of bacterial origin 3 2.15 1.03 1.06 -1.04 1.33 1.63 1.06
adaptive immune response 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
organ or tissue specific immune response 7 1.24 1.06 1.29 -1.06 1.56 1.62 1.43
immune effector process 20 1.79 -1.15 1.28 -1.11 1.26 1.41 1.26
activation of immune response 1 1.17 1.46 1.63 1.36 1.42 1.78 1.19
myeloid leukocyte activation 1 2.18 -2.11 2.19 1.49 1.48 1.37 1.38
immune system process 193 1.3 -1.15 -1.02 -1.12 1.05 1.17 1.2
mucosal immune response 7 1.24 1.06 1.29 -1.06 1.56 1.62 1.43
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 3 1.28 -1.17 2.05 1.18 1.64 1.24 1.18
inflammatory response to antigenic stimulus 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
acute inflammatory response to antigenic stimulus 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
production of molecular mediator of immune response 2 -1.54 1.11 1.81 1.12 1.7 3.17 1.43
leukocyte mediated immunity 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
immune system development 52 1.16 1.07 1.33 1.05 1.3 1.2 1.34
hypersensitivity 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
acute inflammatory response 3 -1.45 1.14 1.29 1.15 1.43 -1.36 1.17
regulation of immune system process 73 1.33 -1.01 1.08 -1.01 1.11 1.27 1.26
negative regulation of immune system process 16 1.45 1.01 1.09 -1.01 1.17 1.27 1.37
positive regulation of immune system process 8 1.43 1.03 1.15 1.01 1.19 1.8 1.48
regulation of immune effector process 36 1.47 -1.08 1.0 -1.04 1.04 1.31 1.19
positive regulation of immune effector process 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
regulation of production of molecular mediator of immune response 34 1.45 -1.09 -1.02 -1.05 1.03 1.32 1.2
positive regulation of production of molecular mediator of immune response 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
regulation of antimicrobial humoral response 39 1.26 -1.07 1.01 -1.04 1.05 1.16 1.17
antimicrobial peptide production 2 -1.54 1.11 1.81 1.12 1.7 3.17 1.43
antifungal peptide production 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
regulation of antimicrobial peptide production 34 1.45 -1.09 -1.02 -1.05 1.03 1.32 1.2
regulation of antibacterial peptide production 19 1.47 -1.12 1.02 -1.12 1.06 1.26 1.29
regulation of antifungal peptide production 7 2.0 -1.32 -1.17 1.03 1.03 1.92 1.18
peptide secretion 1 1.36 -1.09 1.47 1.03 1.67 -1.23 2.47
regulation of peptide secretion 1 1.12 1.15 1.24 1.0 1.0 1.1 -1.06
positive regulation of peptide secretion 1 1.12 1.15 1.24 1.0 1.0 1.1 -1.06
positive regulation of antifungal peptide production 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
regulation of antimicrobial peptide biosynthetic process 34 1.45 -1.09 -1.02 -1.05 1.03 1.32 1.2
negative regulation of antimicrobial peptide biosynthetic process 2 1.03 1.14 1.57 1.07 1.57 -1.03 -1.32
positive regulation of antimicrobial peptide biosynthetic process 23 1.75 -1.22 -1.09 -1.11 -1.01 1.39 1.29
regulation of antibacterial peptide biosynthetic process 19 1.47 -1.12 1.02 -1.12 1.06 1.26 1.29
negative regulation of antibacterial peptide biosynthetic process 2 1.03 1.14 1.57 1.07 1.57 -1.03 -1.32
regulation of antifungal peptide biosynthetic process 6 2.45 -1.42 -1.16 -1.01 -1.05 1.77 1.2
regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria 7 1.96 -1.11 1.11 -1.19 1.09 1.65 1.22
negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria 2 1.03 1.14 1.57 1.07 1.57 -1.03 -1.32
regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria 4 1.05 -1.9 -2.24 -1.85 -1.9 -1.18 1.68
regulation of response to biotic stimulus 44 1.36 -1.07 1.05 -1.02 1.04 1.11 1.1
negative regulation of response to biotic stimulus 7 1.37 1.0 1.62 1.21 1.38 -1.12 -1.13
positive regulation of response to biotic stimulus 1 8.35 -1.25 -1.3 -1.07 -1.15 1.62 -1.07
regulation of humoral immune response 39 1.26 -1.07 1.01 -1.04 1.05 1.16 1.17
negative regulation of humoral immune response 4 1.35 1.1 1.46 1.15 1.8 1.12 1.2
generation of a signal involved in cell-cell signaling 101 -1.07 1.04 1.24 1.13 1.26 1.1 1.03
regionalization 378 1.18 1.05 1.18 1.02 1.22 1.26 1.24
developmental process involved in reproduction 482 1.13 1.1 1.22 1.05 1.26 1.18 1.17
heart morphogenesis 12 1.02 -1.01 1.12 1.1 1.36 1.23 1.2
system process 634 1.08 1.03 1.09 -1.0 1.08 1.15 1.06
skeletal muscle contraction 2 -1.89 -1.52 -1.42 -1.43 -1.62 -1.61 2.67
voluntary skeletal muscle contraction 1 -1.18 -1.0 1.06 -1.02 -1.12 1.04 1.04
muscle system process 13 1.35 -1.07 1.09 -1.24 1.12 1.46 1.24
circulatory system process 8 1.03 1.14 -1.1 1.05 1.17 1.15 1.14
renal system process 6 -4.46 1.18 -1.92 -1.14 -3.52 -1.44 -1.93
heart process 8 1.03 1.14 -1.1 1.05 1.17 1.15 1.14
detection of carbon dioxide 2 -1.18 -1.02 1.02 -1.08 -1.1 -1.05 -1.18
negative regulation of heart induction by canonical Wnt receptor signaling pathway 3 1.09 1.1 1.13 1.08 1.18 1.14 2.09
outflow tract morphogenesis 3 -1.03 1.08 1.55 1.17 2.15 1.03 1.48
regulation of organ formation 8 1.56 -1.2 -1.1 1.04 1.14 1.2 -1.02
endothelium development 3 1.7 1.01 1.41 -1.21 1.32 4.52 2.14
Wnt receptor signaling pathway involved in heart development 3 1.09 1.1 1.13 1.08 1.18 1.14 2.09
amino acid transmembrane transport 30 -1.61 -1.12 -1.51 -1.16 -1.02 -1.08 -1.1
epithelial cell morphogenesis 9 1.12 1.09 1.33 1.05 1.18 1.38 1.22
apical constriction 4 -1.26 1.28 1.59 1.06 1.39 1.15 1.23
cytoneme morphogenesis 2 -1.85 -1.12 1.68 1.29 1.66 1.71 -2.53
neural retina development 1 -1.1 -1.15 -1.07 -1.18 1.52 1.28 1.24
nucleic acid binding 1407 1.18 1.11 1.19 1.1 1.2 1.16 1.11
DNA binding 669 1.15 1.09 1.17 1.08 1.17 1.12 1.11
DNA helicase activity 34 1.08 1.15 1.32 1.19 1.42 1.11 1.09
AT DNA binding 5 1.49 -1.14 -1.13 1.14 1.47 1.04 1.12
bent DNA binding 2 1.7 1.14 1.37 1.1 1.36 1.18 1.22
chromatin binding 72 1.18 1.18 1.3 1.16 1.38 1.26 1.23
lamin binding 1 1.4 1.14 1.18 1.58 1.38 1.2 1.19
damaged DNA binding 15 1.32 1.12 1.34 1.15 1.3 1.19 1.11
DNA clamp loader activity 3 1.23 1.05 1.23 1.24 1.24 1.1 -1.01
double-stranded DNA binding 10 1.24 1.11 1.11 1.14 1.22 1.09 -1.07
satellite DNA binding 5 1.25 1.13 1.51 1.21 1.5 1.17 1.18
single-stranded DNA binding 13 -1.04 1.24 1.4 1.15 1.2 1.2 1.1
sequence-specific DNA binding transcription factor activity 411 1.09 1.04 1.09 1.01 1.1 1.11 1.09
transcription from RNA polymerase I promoter 6 1.31 1.13 1.31 1.22 1.28 1.23 1.04
transcription from RNA polymerase II promoter 91 1.33 1.12 1.23 1.17 1.25 1.17 1.11
copper ion transport 7 -1.13 1.18 1.31 1.05 -1.07 1.09 1.04
sequence-specific distal enhancer binding RNA polymerase II transcription factor activity 50 1.18 -1.11 -1.01 -1.13 -1.1 1.13 1.1
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity 20 1.3 1.06 1.02 -1.03 1.08 1.23 1.26
steroid hormone receptor activity 19 1.11 1.08 1.02 -1.0 1.09 1.16 1.16
retinoic acid receptor activity 1 1.03 1.25 1.07 1.02 1.08 1.24 1.08
transcription from RNA polymerase III promoter 12 1.28 1.21 1.25 1.18 1.32 1.03 1.12
regulation of transcription elongation, DNA-dependent 18 -1.27 1.2 1.28 -1.03 -1.04 -1.12 1.41
transcription cofactor activity 90 1.26 1.11 1.26 1.16 1.34 1.25 1.15
transcription coactivator activity 41 1.32 1.06 1.24 1.13 1.34 1.33 1.18
transcription corepressor activity 19 1.19 1.16 1.26 1.18 1.37 1.12 1.16
transcription termination, DNA-dependent 2 -1.11 1.05 1.39 1.1 1.37 1.26 -1.23
termination of RNA polymerase II transcription 1 -1.51 -1.02 1.38 1.04 1.42 1.11 -1.1
cytoplasmic sequestering of transcription factor 4 2.74 1.08 1.33 1.02 1.2 2.19 1.75
RNA binding 381 1.26 1.16 1.26 1.13 1.22 1.27 1.13
RNA helicase activity 45 1.22 1.23 1.32 1.18 1.31 1.38 1.21
double-stranded RNA binding 16 1.33 -1.04 1.19 -1.13 1.16 1.42 1.51
double-stranded RNA adenosine deaminase activity 1 1.13 1.14 1.55 1.01 1.4 2.0 1.26
single-stranded RNA binding 20 1.32 1.14 1.42 1.11 1.32 1.44 1.23
mRNA binding 170 1.24 1.17 1.28 1.15 1.25 1.26 1.16
mRNA 3'-UTR binding 17 1.34 1.14 1.46 1.02 1.31 1.89 1.29
ribonucleoprotein complex 427 1.18 1.1 1.2 1.16 1.24 1.21 -1.02
small nuclear ribonucleoprotein complex 54 1.14 1.14 1.25 1.27 1.31 1.06 -1.02
structural constituent of ribosome 167 1.21 1.04 1.14 1.12 1.17 1.28 -1.18
translation initiation factor activity 53 1.33 1.18 1.26 1.09 1.18 1.35 1.16
translation elongation factor activity 16 1.48 1.11 1.26 1.06 1.23 1.46 1.05
translation release factor activity 7 1.27 1.16 1.25 1.13 1.18 1.49 1.09
regulation of cell cycle 240 1.19 1.13 1.28 1.13 1.34 1.28 1.16
protein folding 118 1.15 1.04 1.09 1.13 1.17 1.02 1.01
peptidyl-prolyl cis-trans isomerase activity 26 1.38 1.03 1.1 1.15 1.25 1.1 1.02
protein disulfide isomerase activity 10 1.1 -1.01 1.22 1.11 1.12 1.08 1.12
chromatin assembly or disassembly 34 1.01 1.07 1.29 1.13 1.25 -1.04 1.07
nucleosome assembly 27 1.02 1.05 1.3 1.15 1.22 -1.07 1.03
nucleosome organization 36 1.09 1.07 1.28 1.16 1.21 1.01 1.03
histone binding 10 1.48 1.07 1.28 1.23 1.28 1.39 1.04
histone exchange 7 1.15 1.19 1.23 1.17 1.15 1.2 1.05
ATPase activity, coupled 283 -1.01 1.06 1.16 1.03 1.13 1.15 1.04
chaperone binding 16 -1.03 -1.17 1.06 1.16 1.34 1.16 -1.27
response to unfolded protein 2 1.04 1.38 1.16 -1.1 1.05 1.03 1.56
protein refolding 7 1.25 1.05 1.14 -1.0 1.11 -1.26 1.35
motor activity 76 -1.02 1.07 1.2 1.02 1.14 1.1 1.03
microtubule motor activity 51 1.03 1.09 1.15 1.06 1.12 1.1 1.04
axoneme 14 -1.03 1.04 1.03 1.02 -1.05 -1.01 -1.1
muscle contraction 12 1.16 -1.04 1.06 -1.18 1.13 1.33 1.25
contractile fiber 33 2.45 -1.47 -1.08 -1.25 1.2 1.97 -1.14
actin binding 114 -1.07 1.06 1.38 -1.0 1.31 1.09 1.15
protein binding, bridging 17 -1.01 1.02 1.14 1.03 1.09 1.16 1.1
actin filament binding 8 -1.01 -1.14 1.31 -1.17 1.11 1.2 1.33
actin filament bundle assembly 17 1.57 -1.02 1.24 -1.1 1.24 1.29 1.51
barbed-end actin filament capping 2 -1.38 -1.03 2.18 1.01 1.59 -1.39 -1.04
actin monomer binding 1 -3.23 -1.14 1.86 -1.09 2.26 -4.44 -1.1
actin filament depolymerization 4 -1.06 1.03 1.27 1.14 1.25 -1.37 -1.31
actin cytoskeleton organization 160 1.17 1.02 1.34 -1.03 1.29 1.3 1.17
membrane 2078 1.02 -1.01 1.0 -1.02 1.04 1.09 1.03
regulation of actin filament length 20 -1.48 1.08 1.45 1.05 1.38 -1.21 1.18
defense response 178 1.35 -1.27 -1.19 -1.18 -1.1 1.18 1.09
acute-phase response 1 1.84 1.22 1.59 1.61 1.65 1.41 1.04
lysozyme activity 14 1.98 -1.64 -2.07 -1.66 -1.61 -1.16 1.06
defense response to bacterium 84 1.33 -1.21 -1.16 -1.18 -1.05 1.15 1.15
male-specific defense response to bacterium 1 -1.1 -1.03 -1.03 -1.0 -1.23 -1.2 -1.1
defense response to fungus 28 1.68 -1.27 -1.31 -1.29 -1.25 1.08 1.24
response to virus 12 2.35 -1.64 -1.09 -1.61 1.07 1.84 1.26
serine-type endopeptidase activity 263 -2.24 -1.42 -1.67 -1.14 -1.46 -2.32 -1.65
blood coagulation 1 1.05 1.37 1.17 1.34 1.05 1.15 1.1
protein-glutamine gamma-glutamyltransferase activity 2 5.84 -1.94 -1.03 -1.59 -1.03 2.32 1.28
antigen binding 1 -1.71 -1.18 -1.3 -1.15 -1.23 -1.3 1.07
catalytic activity 3804 -1.08 -1.02 -1.07 1.01 1.04 -1.07 -1.05
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 1 1.32 -4.96 -6.02 -4.98 -1.62 7.64 -3.94
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 1 3.18 1.02 1.47 1.11 1.44 4.09 2.36
beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity 1 3.39 -1.12 1.06 -1.11 1.06 1.27 -1.12
beta-alanyl-dopamine hydrolase activity 1 -1.31 -1.76 1.72 1.22 1.97 3.11 1.28
beta-alanyl-dopamine synthase activity 1 1.36 1.09 1.02 -1.03 -1.16 1.04 1.01
beta-carotene 15,15'-monooxygenase activity 1 1.12 -1.01 1.14 1.06 1.09 1.14 -1.06
beta-galactoside alpha-2,6-sialyltransferase activity 1 1.19 1.12 1.07 1.08 1.03 1.22 -1.05
beta-ureidopropionase activity 1 17.28 -3.07 -1.83 -2.92 -2.4 3.32 1.6
gamma-glutamylcyclotransferase activity 2 1.29 1.27 1.3 -1.14 -1.14 1.15 -1.11
gamma-glutamyltransferase activity 4 1.24 -1.34 -1.15 1.08 1.94 1.31 -1.06
1-acylglycerol-3-phosphate O-acyltransferase activity 6 -1.56 -1.19 -1.0 1.18 2.24 -2.62 -1.99
1-pyrroline-5-carboxylate dehydrogenase activity 3 1.56 -1.48 -1.15 -1.62 -1.43 2.14 1.15
1,3-beta-D-glucan synthase activity 1 12.72 -1.88 -1.16 -3.3 -1.54 3.13 2.87
1,4-alpha-glucan branching enzyme activity 1 3.55 -1.35 -1.97 1.08 1.09 1.58 1.19
1-alkyl-2-acetylglycerophosphocholine esterase activity 1 3.85 1.07 1.8 1.09 1.57 2.16 1.8
2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity 5 -4.34 1.01 1.27 1.24 1.5 -3.41 -1.26
3-beta-hydroxy-delta5-steroid dehydrogenase activity 1 7.52 -1.63 -1.52 -1.44 -1.48 2.76 1.78
3-hydroxyacyl-CoA dehydrogenase activity 4 1.05 1.0 -1.41 1.24 -1.28 1.08 1.21
3-hydroxyisobutyryl-CoA hydrolase activity 1 1.35 1.24 1.18 -1.16 -1.11 6.95 -1.22
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 2 1.67 1.29 1.69 -1.02 1.34 1.99 1.11
3-oxo-5-alpha-steroid 4-dehydrogenase activity 1 -1.31 1.28 -1.32 1.3 1.08 -2.32 -1.18
4-aminobutyrate transaminase activity 1 -1.88 3.07 -1.92 -1.52 -1.3 -2.05 1.06
4-hydroxyphenylpyruvate dioxygenase activity 1 1.86 -1.07 1.21 1.03 1.14 1.09 -1.06
4-nitrophenylphosphatase activity 9 -1.32 1.18 -1.3 1.06 1.01 -1.31 1.07
5-aminolevulinate synthase activity 1 1.58 1.36 -1.31 -1.09 -1.26 1.25 1.23
6-phosphofructokinase activity 1 2.63 -1.22 -1.22 1.02 -1.12 5.11 1.3
6-phosphofructo-2-kinase activity 1 1.09 -1.34 2.59 -1.04 1.14 3.38 -1.06
6-pyruvoyltetrahydropterin synthase activity 1 2.12 1.31 1.32 1.23 1.73 1.01 2.0
AMP deaminase activity 1 1.21 1.11 1.3 -1.14 1.24 3.4 1.06
ATP citrate synthase activity 4 -1.02 -1.02 -1.04 -1.09 -1.21 1.05 -1.32
protein C-terminal carboxyl O-methyltransferase activity 1 -2.13 1.18 1.09 1.41 1.8 -1.71 -1.76
CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity 1 2.1 -1.04 1.71 -1.1 1.9 -1.29 1.13
CDP-diacylglycerol-serine O-phosphatidyltransferase activity 1 1.61 1.37 2.22 1.0 1.13 1.67 1.83
D-amino-acid oxidase activity 2 -2.82 -1.69 -2.22 1.7 1.95 -1.63 -1.83
DNA (cytosine-5-)-methyltransferase activity 2 1.2 1.07 1.01 1.32 1.13 -1.12 -1.02
DNA-directed DNA polymerase activity 18 1.05 1.09 1.17 1.07 1.16 1.1 -1.1
DNA primase activity 2 1.15 1.13 1.17 1.19 1.37 1.14 -1.16
DNA-directed RNA polymerase activity 28 1.31 1.12 1.19 1.24 1.24 1.06 1.0
deoxyribodipyrimidine photo-lyase activity 1 -1.34 -1.01 -1.03 1.23 1.09 -1.47 -1.1
DNA-(apurinic or apyrimidinic site) lyase activity 5 1.72 -1.0 1.07 1.11 1.19 1.32 1.0
methylated-DNA-[protein]-cysteine S-methyltransferase activity 1 1.12 -1.01 1.19 1.74 1.2 1.06 -1.09
DNA ligase activity 3 1.18 1.28 1.26 1.14 1.32 1.13 1.13
DNA ligase (ATP) activity 2 1.29 1.46 1.49 1.24 1.5 1.27 1.28
DNA photolyase activity 3 1.02 -1.07 -1.02 1.07 1.04 1.25 -1.04
DNA (6-4) photolyase activity 1 1.03 -1.11 1.01 -1.14 1.01 1.07 -1.17
DNA topoisomerase activity 7 1.03 1.16 1.23 1.17 1.3 1.13 1.25
DNA topoisomerase type I activity 3 -1.14 1.27 1.28 1.28 1.24 1.04 1.14
DNA topoisomerase (ATP-hydrolyzing) activity 3 -1.26 1.43 1.56 1.29 1.52 1.12 1.27
FMN adenylyltransferase activity 2 1.48 1.18 1.47 1.03 -1.01 1.23 1.07
GMP synthase activity 1 1.14 1.09 1.34 -1.05 1.24 1.35 2.12
GMP synthase (glutamine-hydrolyzing) activity 1 1.14 1.09 1.34 -1.05 1.24 1.35 2.12
GPI-anchor transamidase activity 1 1.21 1.1 1.8 1.25 1.66 -1.16 1.35
synaptic vesicle uncoating 2 -1.44 1.22 1.71 1.06 1.91 1.53 1.42
vesicle-mediated transport 402 1.05 1.08 1.23 1.09 1.24 1.19 1.14
protein import into nucleus 36 1.11 1.22 1.35 1.2 1.37 1.25 1.17
cytoskeleton organization 516 1.14 1.08 1.28 1.06 1.28 1.2 1.11
secretion 145 -1.04 1.05 1.22 1.11 1.24 1.07 1.07
GTP cyclohydrolase activity 1 33.5 -5.63 -5.79 -6.03 -4.58 -1.32 6.94
GTP cyclohydrolase I activity 1 33.5 -5.63 -5.79 -6.03 -4.58 -1.32 6.94
hydrogen ion transporting ATP synthase activity, rotational mechanism 16 1.35 -1.04 1.11 -1.09 -1.01 1.54 -1.13
IMP cyclohydrolase activity 1 -1.39 1.0 -1.49 -1.01 -1.06 1.63 -1.09
IMP dehydrogenase activity 1 1.16 1.34 1.12 1.03 1.08 -1.1 1.99
L-iditol 2-dehydrogenase activity 3 1.17 -1.39 -1.37 1.12 1.23 1.74 -1.02
L-iduronidase activity 1 -1.71 1.0 1.11 -1.04 1.62 -1.12 -1.27
N-acetylgalactosamine-4-sulfatase activity 4 1.55 -1.16 -1.4 1.09 1.42 2.61 -1.17
N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity 3 -1.38 1.01 1.13 1.06 1.15 -1.4 1.08
NAD+ ADP-ribosyltransferase activity 1 -2.18 1.38 1.41 1.1 1.13 -1.47 1.05
NAD+ kinase activity 3 1.2 1.17 -1.08 1.1 1.06 -1.04 1.02
NAD+ synthase (glutamine-hydrolyzing) activity 1 2.07 1.6 1.04 1.19 1.4 2.13 1.77
NADH dehydrogenase activity 36 1.13 1.03 1.27 1.06 1.1 1.72 -1.29
NAD(P)+-protein-arginine ADP-ribosyltransferase activity 2 1.3 1.3 1.14 1.02 1.15 -1.14 1.12
NADPH-hemoprotein reductase activity 1 1.63 1.35 1.12 -1.0 1.2 -1.04 1.34
NADPH dehydrogenase activity 1 -1.51 1.45 1.08 1.06 -1.12 -1.58 -1.42
RNA-3'-phosphate cyclase activity 2 1.22 1.13 -1.15 1.27 1.07 -1.19 -1.17
RNA-directed DNA polymerase activity 1 1.54 1.82 1.92 -1.04 1.87 1.15 2.39
UDP-N-acetylglucosamine diphosphorylase activity 1 -1.57 -1.13 1.65 -1.09 1.26 -1.83 1.72
UDP-glucose 4-epimerase activity 3 -1.33 1.08 -1.17 -1.19 -1.1 -1.47 1.1
UDP-glucose:glycoprotein glucosyltransferase activity 1 1.21 1.16 1.35 -1.04 1.59 1.69 2.54
UTP:glucose-1-phosphate uridylyltransferase activity 1 1.07 -1.0 -1.14 -1.11 -1.05 -1.01 1.08
acetyl-CoA C-acetyltransferase activity 2 1.25 1.16 -1.11 1.2 -1.13 1.26 -1.35
acetate-CoA ligase activity 2 1.63 1.11 -1.36 -1.04 -1.71 1.16 1.18
acetyl-CoA C-acyltransferase activity 4 1.58 1.11 -1.25 1.12 1.08 1.06 -1.32
acetyl-CoA carboxylase activity 1 7.73 1.2 -1.41 -2.71 1.2 3.14 4.69
acetylcholinesterase activity 1 2.27 1.23 -5.17 -1.59 -2.2 -9.9 9.42
acid phosphatase activity 12 1.44 1.13 -1.05 -1.03 -1.02 1.81 1.28
aconitate hydratase activity 4 1.11 1.25 1.22 -1.14 -1.03 1.75 1.32
acyl-CoA dehydrogenase activity 15 -1.17 1.11 -1.37 1.1 1.1 -1.79 -1.3
acyl-CoA oxidase activity 6 -2.19 1.03 -1.7 1.08 1.14 -3.66 -1.47
acylphosphatase activity 6 1.57 1.0 -1.02 1.01 -1.1 1.04 -1.12
adenine phosphoribosyltransferase activity 1 1.17 1.37 1.23 1.24 1.3 1.33 -1.5
adenosine deaminase activity 8 -1.69 1.1 1.06 -1.03 -1.09 1.15 -1.16
adenosine kinase activity 4 1.16 1.08 -1.11 1.18 1.12 1.14 -1.1
ATP-dependent DNA helicase activity 19 1.12 1.17 1.33 1.14 1.3 1.15 1.17
ATP-dependent RNA helicase activity 38 1.22 1.21 1.3 1.2 1.31 1.37 1.16
cation-transporting ATPase activity 26 1.1 1.0 1.24 -1.08 1.02 1.51 -1.05
metal ion transmembrane transporter activity 144 -1.31 -1.08 -1.41 -1.18 -1.18 1.02 -1.13
copper-exporting ATPase activity 1 -2.22 1.33 3.02 1.07 -1.16 -1.12 1.08
ATPase activity, coupled to transmembrane movement of substances 120 -1.08 -1.04 1.03 -1.07 1.02 1.16 -1.05
ATP-binding cassette (ABC) transporter complex 41 1.23 -1.2 -1.24 -1.08 1.0 1.04 -1.04
phospholipid-translocating ATPase activity 6 -2.65 1.11 -1.12 1.22 1.24 -1.33 -1.09
adenosylhomocysteinase activity 3 -2.93 -1.82 -1.21 -1.07 1.22 1.86 -1.16
adenosylmethionine decarboxylase activity 1 1.82 1.07 1.08 1.22 1.03 1.75 -1.05
adenylate cyclase activity 12 1.43 1.1 1.07 -1.04 1.13 1.5 1.22
adenylate kinase activity 6 1.61 -1.18 1.01 1.04 1.05 1.04 -1.33
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity 1 1.1 1.08 1.31 1.11 1.27 1.3 1.19
adenylosuccinate synthase activity 1 2.08 1.19 1.56 -1.1 -1.15 1.56 -1.05
adenylylsulfate kinase activity 1 -2.63 1.06 1.41 1.07 1.11 -1.64 -1.02
L-alanine:2-oxoglutarate aminotransferase activity 1 -2.33 1.13 1.14 1.09 1.76 1.77 -1.09
alcohol dehydrogenase (NAD) activity 5 1.66 -1.09 -1.8 -1.39 -1.21 1.37 1.27
aldehyde dehydrogenase (NAD) activity 3 -1.65 1.15 -1.65 1.05 -1.41 -1.9 -1.31
aldehyde dehydrogenase [NAD(P)+] activity 1 1.67 -1.24 -1.26 1.36 2.03 -1.43 1.25
alditol:NADP+ 1-oxidoreductase activity 6 -1.18 1.24 -1.3 -1.16 -1.25 -1.07 1.15
aldo-keto reductase (NADP) activity 7 1.25 1.15 -1.37 -1.18 -1.21 1.14 1.22
aldose 1-epimerase activity 3 -1.46 1.17 -1.47 -1.07 1.13 -1.58 -1.03
alkaline phosphatase activity 13 -5.32 -1.81 -4.2 -1.19 -1.19 -4.42 -4.05
allantoinase activity 1 2.85 -1.01 1.16 1.03 -1.08 1.74 -1.1
amidase activity 1 1.54 -1.32 2.9 1.39 -1.83 -6.19 -2.79
amidophosphoribosyltransferase activity 2 1.11 1.02 -1.15 -1.13 -1.43 1.89 -1.09
aminoacyl-tRNA hydrolase activity 3 1.72 -1.02 1.14 1.1 1.0 1.49 -1.08
aminoacylase activity 6 -1.72 -1.86 -1.07 -1.63 1.29 -1.6 -1.71
aminomethyltransferase activity 4 1.27 1.14 1.17 1.01 -1.01 1.6 1.08
nucleoside-diphosphatase activity 3 -2.29 1.44 -2.09 1.33 -1.38 -3.32 1.1
nucleoside-triphosphatase activity 535 1.04 1.07 1.18 1.06 1.16 1.12 1.03
arginase activity 2 1.73 -1.09 1.02 -1.05 -1.18 2.27 1.17
arginine kinase activity 3 1.01 1.07 1.29 1.05 -1.11 1.23 -1.22
argininosuccinate synthase activity 1 -31.89 1.77 -20.72 1.41 1.0 -12.66 -3.5
argininosuccinate lyase activity 1 -15.39 1.51 -7.96 1.39 1.15 -4.77 -1.11
arginyltransferase activity 1 1.03 1.39 1.46 1.24 1.37 1.69 1.36
aromatic-L-amino-acid decarboxylase activity 4 2.04 -1.66 -1.74 -1.59 -1.59 1.51 1.84
aralkylamine N-acetyltransferase activity 1 -8.98 1.77 -2.05 -1.02 -2.08 -14.22 1.22
arylamine N-acetyltransferase activity 1 -8.98 1.77 -2.05 -1.02 -2.08 -14.22 1.22
aryl sulfotransferase activity 1 1.25 -1.11 -1.17 -1.08 -1.01 1.11 1.01
aryldialkylphosphatase activity 1 1.9 -1.44 -1.39 -2.02 1.17 21.38 -1.25
asparagine synthase (glutamine-hydrolyzing) activity 2 -1.07 1.2 1.14 1.26 1.17 1.27 -1.14
asparaginase activity 4 1.31 -1.05 -1.24 -1.15 1.04 1.97 1.03
aspartate 1-decarboxylase activity 1 1.44 -1.11 -1.15 1.16 -1.17 -1.1 -1.2
L-aspartate:2-oxoglutarate aminotransferase activity 2 1.83 1.18 -1.32 -1.0 1.19 1.57 1.14
aspartate carbamoyltransferase activity 1 -1.12 1.14 1.63 1.21 1.33 1.0 1.05
biliverdin reductase activity 1 -1.51 1.45 1.08 1.06 -1.12 -1.58 -1.42
biotin carboxylase activity 3 2.88 1.25 -1.21 -1.16 -1.0 2.26 1.91
biotin-[acetyl-CoA-carboxylase] ligase activity 1 1.43 1.46 1.44 1.24 1.28 1.18 1.38
biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity 1 1.43 1.46 1.44 1.24 1.28 1.18 1.38
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity 1 -1.85 1.12 1.37 1.12 1.23 -1.02 1.02
branched-chain-amino-acid transaminase activity 1 5.21 1.63 1.44 -1.45 -2.46 1.42 2.6
carbamoyl-phosphate synthase (ammonia) activity 1 -1.12 1.14 1.63 1.21 1.33 1.0 1.05
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 1 -1.12 1.14 1.63 1.21 1.33 1.0 1.05
carbonate dehydratase activity 17 -1.34 -1.07 1.2 -1.25 1.01 1.12 1.01
carbonyl reductase (NADPH) activity 3 1.57 1.0 -1.52 -1.25 -1.09 1.43 1.09
carboxylesterase activity 33 -1.1 1.01 -1.29 -1.03 -1.13 -1.36 -1.13
carnitine O-acetyltransferase activity 3 -1.35 1.07 -1.21 1.11 1.17 -1.19 -1.2
carnitine O-palmitoyltransferase activity 1 1.55 1.41 -1.09 1.13 1.34 -1.06 1.05
catalase activity 3 1.88 -1.66 -2.02 -1.59 -1.55 2.15 -1.21
catechol oxidase activity 1 1.73 1.33 1.02 1.13 -1.06 -1.05 1.06
chitin deacetylase activity 2 2.14 -1.13 1.05 -1.06 -1.29 -1.18 -1.25
chitin synthase activity 2 -4.74 1.25 1.37 -1.3 1.38 1.09 1.15
choline O-acetyltransferase activity 1 1.49 -1.03 -1.23 1.03 1.04 -1.13 1.06
choline kinase activity 2 1.11 1.13 1.36 1.19 1.43 2.57 1.13
cholinesterase activity 2 -1.12 1.28 -2.63 -1.13 -1.28 -3.75 2.43
choline-phosphate cytidylyltransferase activity 2 1.06 -1.23 1.07 1.02 1.15 -1.4 1.55
citrate (Si)-synthase activity 1 -1.05 1.1 -1.11 1.07 -1.23 -1.06 -1.08
coproporphyrinogen oxidase activity 1 -1.38 1.31 1.39 1.26 1.22 -1.88 -1.39
cyclic-nucleotide phosphodiesterase activity 8 1.68 1.07 1.28 1.01 1.26 2.25 1.48
3',5'-cyclic-nucleotide phosphodiesterase activity 8 1.68 1.07 1.28 1.01 1.26 2.25 1.48
3',5'-cyclic-AMP phosphodiesterase activity 4 1.06 1.26 1.31 1.05 1.3 1.79 1.4
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity 1 -1.09 -1.0 1.07 1.3 -1.04 -1.15 -1.07
cystathionine beta-synthase activity 1 1.25 1.1 1.48 -1.98 -7.11 -1.17 2.59
cystathionine gamma-lyase activity 2 1.42 1.32 1.04 1.04 1.07 -1.09 1.37
cytidine deaminase activity 3 -2.8 1.04 -1.39 1.2 1.32 -1.87 -1.06
cytidylate kinase activity 1 -1.35 1.03 1.12 1.16 1.1 -1.2 -1.23
cytochrome-b5 reductase activity 1 -1.1 1.03 -1.07 1.37 1.05 -1.32 1.01
cytochrome-c oxidase activity 18 -1.12 -1.08 1.07 -1.07 1.03 1.19 -1.31
cytosine deaminase activity 1 1.58 1.21 -1.04 1.33 -1.0 -1.93 1.34
dCMP deaminase activity 1 2.54 -1.17 -1.05 1.35 1.96 1.77 -1.1
glycogen debranching enzyme activity 1 1.91 -1.57 -1.98 1.36 -1.16 2.47 1.07
4-alpha-glucanotransferase activity 1 1.91 -1.57 -1.98 1.36 -1.16 2.47 1.07
amylo-alpha-1,6-glucosidase activity 1 1.91 -1.57 -1.98 1.36 -1.16 2.47 1.07
deoxyribose-phosphate aldolase activity 1 -1.52 1.52 -1.38 1.37 -1.06 -2.8 1.21
dephospho-CoA kinase activity 2 1.04 1.25 -1.2 1.45 1.19 -1.52 -1.32
diacylglycerol cholinephosphotransferase activity 1 -3.65 1.65 3.17 1.08 1.15 -2.09 2.51
diacylglycerol kinase activity 8 1.65 1.05 -1.03 -1.02 -1.04 1.17 1.24
diacylglycerol O-acyltransferase activity 1 -1.05 1.33 3.49 1.16 1.98 2.09 1.25
dihydrofolate reductase activity 1 2.25 -1.1 -1.03 1.28 1.09 2.14 -1.24
dihydrolipoamide branched chain acyltransferase activity 1 1.74 1.44 1.67 1.01 1.35 1.38 1.19
dihydrolipoyl dehydrogenase activity 1 -1.4 -1.14 2.27 -1.25 -1.48 1.94 -1.5
dihydrolipoyllysine-residue succinyltransferase activity 1 1.27 -1.02 1.79 -1.24 1.05 3.95 -1.37
dihydroorotase activity 1 -1.12 1.14 1.63 1.21 1.33 1.0 1.05
dihydroorotate dehydrogenase activity 2 -1.09 1.44 1.03 1.31 -1.02 -1.29 -1.1
6,7-dihydropteridine reductase activity 1 2.26 1.17 1.35 1.12 1.23 1.64 1.14
dihydropyrimidinase activity 1 -1.0 1.2 1.11 1.02 1.13 1.01 1.16
dihydroorotate oxidase activity 2 -1.09 1.44 1.03 1.31 -1.02 -1.29 -1.1
dihydrouracil dehydrogenase (NAD+) activity 1 -2.4 1.52 -1.09 1.53 -1.18 -2.54 -1.54
dimethylallyltranstransferase activity 2 2.38 1.13 2.21 -1.02 1.58 1.4 1.7
diphosphomevalonate decarboxylase activity 1 2.36 -1.19 -1.1 1.02 -1.17 1.09 1.24
diphthine synthase activity 1 1.75 1.22 1.1 1.3 1.08 -1.18 -1.03
dodecenoyl-CoA delta-isomerase activity 5 1.65 1.02 -1.16 1.25 1.08 1.17 -1.36
dopachrome isomerase activity 2 2.9 -1.22 -1.25 -1.08 -1.28 3.34 -1.14
dolichol kinase activity 1 -2.66 1.27 -1.76 1.39 1.67 -4.72 -1.84
dolichyl-phosphate-mannose-protein mannosyltransferase activity 2 1.57 1.01 1.07 -1.18 -1.11 1.61 1.23
dUTP diphosphatase activity 1 -1.36 -1.27 1.07 1.7 1.82 -3.47 -2.13
peptidyl-lysine modification to hypusine 2 1.15 1.07 1.04 1.07 1.11 1.08 -1.05
deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase 1 -1.3 1.12 1.08 1.3 1.03 -1.14 -1.27
ecdysteroid UDP-glucosyltransferase activity 2 -2.06 1.41 -1.15 1.08 1.07 -2.31 -1.09
electron-transferring-flavoprotein dehydrogenase activity 1 2.09 1.59 -1.41 1.19 1.36 1.02 -1.19
endopeptidase activity 433 -1.75 -1.28 -1.35 -1.08 -1.23 -1.79 -1.45
ATP-dependent peptidase activity 3 -1.2 1.29 1.23 1.11 1.07 1.26 1.04
aminopeptidase activity 36 -2.28 -1.12 -1.52 1.05 1.14 -1.43 -1.98
metalloexopeptidase activity 41 -2.37 -1.56 -1.46 1.02 -1.31 -2.4 -1.85
carboxypeptidase activity 35 -2.91 -1.85 -1.55 -1.01 -1.63 -3.14 -1.86
metallocarboxypeptidase activity 24 -4.15 -2.21 -1.86 -1.01 -1.57 -4.07 -2.61
serine-type carboxypeptidase activity 11 -1.26 -1.29 -1.05 -1.03 -1.8 -1.77 1.1
aspartic-type endopeptidase activity 19 -1.6 -1.03 1.15 -1.16 -1.46 -1.86 -1.32
calcium-dependent cysteine-type endopeptidase activity 4 2.12 1.16 1.44 1.14 1.21 1.24 1.16
apoptotic process 69 1.05 1.06 1.22 1.08 1.24 -1.05 1.11
lysosome 28 -2.58 -1.1 -2.35 1.15 -1.08 -2.06 -3.03
cysteine-type peptidase activity 43 -1.18 -1.07 1.14 -1.01 1.29 -1.03 -1.06
dipeptidyl-peptidase activity 13 -1.05 1.04 -1.41 1.07 1.08 -1.08 1.15
pyroglutamyl-peptidase activity 2 2.37 -1.16 1.04 -1.04 1.14 1.57 1.04
ubiquitin thiolesterase activity 27 1.19 1.22 1.57 1.17 1.42 1.39 1.24
metalloendopeptidase activity 79 -1.34 -1.11 -1.09 1.01 1.06 -1.1 -1.21
dipeptidase activity 7 -1.14 -1.08 -1.07 1.19 1.09 -1.2 -1.2
mitochondrion 480 1.05 1.07 1.13 1.06 1.11 1.38 -1.19
metallopeptidase activity 153 -1.78 -1.24 -1.3 1.02 -1.0 -1.44 -1.51
peptidyl-dipeptidase activity 6 -1.43 -1.17 -1.51 -1.07 1.03 1.0 -1.19
vacuole 54 -2.1 -1.04 -1.32 -1.01 -1.13 -1.28 -1.9
serine-type peptidase activity 288 -2.24 -1.4 -1.61 -1.12 -1.45 -2.28 -1.59
tripeptidyl-peptidase activity 2 -2.48 1.24 -1.3 1.26 1.28 -1.53 -1.15
threonine-type endopeptidase activity 23 1.34 -1.02 1.1 1.11 1.12 -1.15 -1.1
peptidase activity 576 -1.77 -1.28 -1.36 -1.05 -1.15 -1.74 -1.45
enoyl-CoA hydratase activity 5 1.01 1.21 -1.01 1.14 1.18 -1.41 -1.2
epoxide hydrolase activity 3 -2.11 1.3 -1.14 -1.06 -1.44 -4.35 1.38
estradiol 17-beta-dehydrogenase activity 2 1.13 -1.01 -1.43 1.15 1.17 -1.17 -1.46
ethanolamine kinase activity 2 1.11 1.13 1.36 1.19 1.43 2.57 1.13
ethanolamine-phosphate cytidylyltransferase activity 1 1.81 -1.85 1.07 -1.42 1.03 1.7 2.82
ethanolaminephosphotransferase activity 1 -1.35 1.28 1.66 1.08 1.2 1.32 1.18
farnesyltranstransferase activity 2 1.07 1.18 1.54 1.21 1.32 1.31 -1.04
fatty acid synthase activity 8 1.58 -1.38 -1.32 -1.5 -1.29 1.18 1.72
[acyl-carrier-protein] S-acetyltransferase activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
[acyl-carrier-protein] S-malonyltransferase activity 3 2.14 -1.05 -1.1 -1.07 1.17 1.47 1.42
3-oxoacyl-[acyl-carrier-protein] synthase activity 3 2.25 -1.02 -1.08 -1.11 1.15 1.9 1.44
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
oleoyl-[acyl-carrier-protein] hydrolase activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
fatty-acyl-CoA synthase activity 1 2.47 -1.2 -1.84 1.79 2.31 -2.71 -1.43
ferroxidase activity 3 -1.88 -2.6 -2.43 -2.04 1.07 -1.41 2.03
iron ion transmembrane transporter activity 7 1.31 -1.87 -2.05 -1.74 -1.19 1.52 1.79
ferredoxin-NADP+ reductase activity 1 -1.19 1.24 1.2 1.43 1.53 -1.12 -1.13
tetrahydrofolylpolyglutamate synthase activity 2 -1.63 1.22 -1.26 1.27 -1.21 -1.7 -1.32
S-(hydroxymethyl)glutathione dehydrogenase activity 1 1.29 1.1 1.03 1.22 1.29 1.66 -1.14
formate-tetrahydrofolate ligase activity 1 -2.72 1.36 -1.4 1.55 -1.7 -1.17 -2.58
fructose-2,6-bisphosphate 2-phosphatase activity 1 1.09 -1.34 2.59 -1.04 1.14 3.38 -1.06
fructose-bisphosphate aldolase activity 1 1.83 1.08 -1.27 -1.04 1.23 2.05 1.42
fumarate hydratase activity 4 -1.03 1.03 -1.06 -1.09 -1.22 1.2 -1.26
fumarylacetoacetase activity 1 2.81 -1.06 -1.21 -1.09 1.58 2.01 -1.24
geranyltranstransferase activity 2 2.38 1.13 2.21 -1.02 1.58 1.4 1.7
glucosamine-6-phosphate deaminase activity 1 -1.22 1.14 1.64 1.24 2.02 -2.96 -2.72
glucosamine 6-phosphate N-acetyltransferase activity 1 1.02 1.09 -1.02 1.16 1.08 -1.06 2.5
glucose dehydrogenase activity 4 2.07 -1.33 -1.32 -1.38 -1.39 2.15 -1.49
glucose-6-phosphate dehydrogenase activity 2 1.97 -1.14 -2.0 -1.18 -1.53 1.18 1.65
glucose-6-phosphatase activity 1 1.02 1.09 1.02 1.0 -1.15 -1.1 -1.14
glucose-6-phosphate isomerase activity 1 4.0 1.26 -2.38 -1.3 -1.5 3.87 2.36
glucosylceramidase activity 3 -3.7 -1.06 -2.39 1.57 -1.6 -3.65 -2.05
glutamate 5-kinase activity 1 -29.94 1.93 -2.31 -1.05 -1.13 -7.63 1.24
glutamate-5-semialdehyde dehydrogenase activity 1 -29.94 1.93 -2.31 -1.05 -1.13 -7.63 1.24
glutamate decarboxylase activity 2 1.13 -1.03 -1.11 1.07 -1.17 -1.16 -1.18
glutamate dehydrogenase (NAD+) activity 1 -1.32 -1.9 1.3 -2.14 3.35 4.87 -4.48
glutamate dehydrogenase [NAD(P)+] activity 2 -1.13 -1.34 1.15 -1.41 1.89 2.28 -2.14
glutamate synthase (NADPH) activity 1 2.14 1.19 1.24 1.03 -1.73 3.68 2.51
glutamate-ammonia ligase activity 2 1.91 -1.99 2.01 -1.44 1.52 -1.73 -1.25
glutamate-cysteine ligase activity 2 -1.84 1.49 -1.21 1.04 -1.06 1.03 1.54
glutamine-fructose-6-phosphate transaminase (isomerizing) activity 2 -1.0 -1.44 1.48 -1.44 1.38 1.11 2.78
glutaryl-CoA dehydrogenase activity 1 -1.51 -1.6 -1.42 1.8 -1.74 2.0 -2.55
glutathione-disulfide reductase activity 1 -1.86 1.42 -1.95 1.12 1.15 -1.81 1.13
glutathione synthase activity 1 -4.56 1.3 -1.17 1.44 -1.72 -2.63 -1.17
glutathione transferase activity 36 -1.24 1.1 1.04 -1.09 -1.01 -1.48 -1.09
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity 3 1.41 -1.11 -1.14 -1.08 -1.06 1.76 1.01
glycerol-3-phosphate O-acyltransferase activity 2 3.16 -1.05 -1.54 1.04 2.3 -1.34 1.05
glycerol-3-phosphate dehydrogenase [NAD+] activity 2 1.2 1.12 -1.49 1.16 1.79 -1.21 -1.08
glycerol-3-phosphate dehydrogenase activity 5 -1.02 -1.05 1.01 1.08 1.13 1.19 -1.09
glycerol kinase activity 5 1.42 -1.01 1.08 1.36 1.35 1.01 -1.3
glycine hydroxymethyltransferase activity 1 4.17 -1.15 1.23 1.12 1.08 1.16 -1.19
glycogen (starch) synthase activity 1 3.34 -1.14 1.48 -1.05 1.39 2.94 1.3
glycine decarboxylation via glycine cleavage system 1 1.73 -1.01 1.7 -1.04 1.38 3.31 -1.03
glycine dehydrogenase (decarboxylating) activity 1 -1.37 -1.08 -1.16 -1.21 -1.14 1.68 -1.06
glycolipid mannosyltransferase activity 1 -1.85 1.22 -1.04 1.31 1.1 -2.17 1.06
glycylpeptide N-tetradecanoyltransferase activity 1 -1.49 1.29 1.71 1.24 1.7 1.05 1.0
guanosine-diphosphatase activity 1 -1.51 1.28 -1.3 1.09 -1.1 -3.57 1.37
guanylate cyclase activity 13 -1.19 -1.02 -1.04 1.02 -1.07 -1.19 -1.11
guanylate kinase activity 5 3.22 1.04 1.21 -1.15 1.05 2.62 1.29
receptor binding 174 1.06 -1.15 -1.03 -1.09 1.07 1.13 1.05
cell adhesion 161 1.22 -1.06 1.07 -1.06 1.21 1.38 1.25
integral to membrane 1123 -1.03 -1.03 -1.04 -1.04 -1.01 1.02 -1.0
cell adhesion molecule binding 17 -1.29 -1.01 1.2 -1.06 1.34 -1.06 1.2
helicase activity 105 1.14 1.19 1.33 1.17 1.34 1.27 1.17
heme oxygenase (decyclizing) activity 1 2.0 1.05 2.09 1.06 1.46 2.34 1.12
heparan sulfate 2-O-sulfotransferase activity 2 2.25 1.13 1.26 1.01 1.22 1.54 1.62
hexaprenyldihydroxybenzoate methyltransferase activity 1 -1.1 1.09 1.22 1.29 1.3 1.24 -1.16
hexokinase activity 4 -1.31 1.0 -1.96 1.11 1.37 1.21 -1.77
histidine decarboxylase activity 1 1.05 1.13 1.16 1.21 1.16 1.14 1.09
histone acetyltransferase activity 13 1.18 1.17 1.35 1.18 1.29 1.36 1.21
histone deacetylase activity 8 1.29 1.14 1.07 1.21 1.24 1.41 1.17
holocytochrome-c synthase activity 1 1.66 1.03 1.71 1.06 1.0 2.28 -1.41
homogentisate 1,2-dioxygenase activity 1 -1.11 -1.1 -1.19 1.12 -1.15 -1.2 -1.15
hyalurononglucosaminidase activity 1 1.16 1.5 1.47 1.26 1.67 1.16 1.31
hydroxyacylglutathione hydrolase activity 1 -2.43 1.25 -1.81 1.44 1.13 -2.07 -1.36
hydroxymethylbilane synthase activity 1 -1.1 1.02 -1.19 -1.23 -1.41 1.01 -1.14
hydroxymethylglutaryl-CoA lyase activity 1 -1.23 1.82 1.48 1.33 1.52 1.63 1.08
hydroxymethylglutaryl-CoA synthase activity 1 1.84 -1.29 1.3 -1.14 1.76 1.59 1.19
iduronate-2-sulfatase activity 1 1.62 1.05 1.28 1.01 1.11 1.28 1.12
inorganic diphosphatase activity 3 1.21 -1.0 1.05 1.15 1.08 1.12 -1.14
phosphatidylinositol phosphate kinase activity 6 -1.3 1.22 1.48 1.12 1.58 1.08 1.01
phosphatidylinositol kinase activity 5 -1.09 1.17 1.62 1.11 1.75 1.32 1.12
phosphatidylinositol bisphosphate kinase activity 3 -1.46 1.15 1.53 1.18 1.77 -1.09 -1.14
1-phosphatidylinositol 4-kinase activity 2 1.44 1.21 1.76 1.02 1.71 2.28 1.63
1-phosphatidylinositol-4-phosphate 5-kinase activity 3 -1.16 1.29 1.43 1.06 1.4 1.27 1.16
phosphatidylinositol phospholipase C activity 2 2.58 1.12 1.89 -1.08 1.02 1.84 1.76
phosphatidylinositol bisphosphate phosphatase activity 3 1.28 1.18 1.39 1.05 1.29 1.32 1.32
phosphatidylinositol trisphosphate phosphatase activity 1 2.96 1.13 1.75 -1.2 1.98 1.94 1.75
phosphatidylinositol monophosphate phosphatase activity 2 -1.31 1.16 1.29 1.21 -1.01 1.04 -1.19
inositol phosphate phosphatase activity 13 1.85 -1.04 -1.08 -1.1 1.15 1.89 1.3
phosphatidylinositol-3-phosphatase activity 1 -1.51 1.05 1.08 1.24 -1.11 -1.13 -1.35
inositol-1,4-bisphosphate 1-phosphatase activity 1 3.45 -1.15 1.32 1.0 -1.07 1.6 -1.16
phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity 1 -1.07 1.22 1.09 1.37 -1.04 -1.17 -1.02
inositol trisphosphate phosphatase activity 6 1.66 1.07 1.37 -1.03 1.33 2.5 1.26
inositol-polyphosphate 5-phosphatase activity 3 1.23 1.22 1.55 1.08 1.34 1.47 1.38
isocitrate dehydrogenase activity 7 1.09 1.14 1.28 -1.23 1.01 1.93 1.09
isocitrate dehydrogenase (NAD+) activity 6 1.03 1.08 1.46 -1.19 1.02 2.18 1.06
isocitrate dehydrogenase (NADP+) activity 1 1.5 1.55 -1.65 -1.56 -1.01 -1.09 1.26
isopentenyl-diphosphate delta-isomerase activity 1 3.32 -1.02 1.27 1.26 1.27 1.92 1.53
juvenile-hormone esterase activity 1 1.2 -1.02 -1.01 -1.01 1.01 -1.01 -1.05
ketohexokinase activity 4 1.16 1.19 1.03 1.01 1.17 1.1 -1.01
lactate dehydrogenase activity 2 1.05 1.2 1.7 -1.34 -1.08 -2.44 1.33
L-lactate dehydrogenase activity 2 1.05 1.2 1.7 -1.34 -1.08 -2.44 1.33
lactoylglutathione lyase activity 1 -1.59 1.09 -1.01 1.22 -1.05 -1.39 -1.43
leukotriene-A4 hydrolase activity 1 -1.74 1.11 -2.01 1.51 1.27 -1.87 -1.55
lipoprotein lipase activity 5 -2.69 -1.1 -1.42 1.06 1.23 -1.76 -1.32
long-chain-acyl-CoA dehydrogenase activity 2 1.45 1.45 -1.3 -1.02 1.11 1.33 -1.15
long-chain fatty acid-CoA ligase activity 7 1.81 -1.3 -1.35 1.09 1.2 -1.91 -1.26
lysine N-acetyltransferase activity 1 1.11 1.34 1.12 1.23 1.07 1.27 1.32
malic enzyme activity 4 -1.07 1.26 1.14 -1.52 -1.06 1.05 1.65
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity 4 -1.07 1.26 1.14 -1.52 -1.06 1.05 1.65
mannose-1-phosphate guanylyltransferase activity 2 -2.09 1.14 1.2 1.25 1.24 -1.89 1.17
mannose-6-phosphate isomerase activity 2 3.41 1.03 1.33 -1.05 -1.02 3.9 1.9
methenyltetrahydrofolate cyclohydrolase activity 2 1.63 -1.3 -1.28 -1.04 -1.47 2.82 -1.53
methionine adenosyltransferase activity 1 1.6 1.05 1.23 -1.23 1.41 1.78 1.98
methionyl-tRNA formyltransferase activity 1 1.38 1.09 1.78 1.2 1.53 2.7 -1.25
mRNA (guanine-N7-)-methyltransferase activity 1 1.22 1.12 1.34 1.19 1.11 -1.08 1.0
mRNA guanylyltransferase activity 1 1.69 1.28 1.3 1.3 1.17 1.5 1.34
methylcrotonoyl-CoA carboxylase activity 2 1.38 1.49 1.32 1.28 1.37 1.61 1.17
methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity 1 2.55 -3.49 -3.06 -4.0 -1.9 6.63 -1.86
methylenetetrahydrofolate dehydrogenase (NAD+) activity 1 7.21 -2.31 -1.17 -1.68 -1.27 9.3 1.1
methylenetetrahydrofolate dehydrogenase (NADP+) activity 2 1.63 -1.3 -1.28 -1.04 -1.47 2.82 -1.53
methylenetetrahydrofolate reductase (NADPH) activity 1 1.73 -1.17 -1.14 -1.13 -1.11 2.12 -1.29
methylmalonate-semialdehyde dehydrogenase (acylating) activity 1 -1.74 1.44 -1.08 -1.1 -1.07 1.5 1.28
mevalonate kinase activity 1 1.42 1.16 1.14 1.22 1.05 1.2 -1.02
monooxygenase activity 35 1.52 -1.2 -1.23 -1.13 -1.16 -1.04 1.06
N,N-dimethylaniline monooxygenase activity 2 1.33 1.51 -1.79 -1.37 -1.35 1.43 1.59
dopamine beta-monooxygenase activity 3 1.25 1.07 -1.02 -1.01 1.04 1.12 1.05
ecdysone 20-monooxygenase activity 1 -1.22 -1.23 1.13 -1.06 1.31 -1.16 -1.34
kynurenine 3-monooxygenase activity 1 1.05 1.0 -1.01 1.01 -1.05 -1.09 -1.05
monophenol monooxygenase activity 3 1.29 1.11 -1.09 -1.0 -1.13 -1.11 -1.01
peptidylglycine monooxygenase activity 1 2.74 1.3 1.75 1.08 1.98 1.97 2.28
phenylalanine 4-monooxygenase activity 2 1.24 -1.3 -1.46 -1.42 -1.18 2.11 -1.36
tryptophan 5-monooxygenase activity 2 1.24 -1.3 -1.46 -1.42 -1.18 2.11 -1.36
tyrosine 3-monooxygenase activity 1 -1.05 -1.1 1.05 1.12 -1.1 -1.1 1.78
inositol-3-phosphate synthase activity 1 1.86 -1.46 -1.12 -1.51 1.13 1.83 1.71
nicotinate-nucleotide diphosphorylase (carboxylating) activity 1 8.31 1.05 -1.79 -1.54 -1.19 1.17 2.54
nicotinate phosphoribosyltransferase activity 1 8.31 1.05 -1.79 -1.54 -1.19 1.17 2.54
nitric-oxide synthase activity 1 1.08 1.06 1.02 1.1 1.05 -1.07 -1.02
nuclease activity 79 1.35 1.08 1.23 1.13 1.28 1.26 1.07
endonuclease activity 38 1.44 1.02 1.21 1.09 1.25 1.3 1.05
endodeoxyribonuclease activity 15 1.39 -1.02 1.1 -1.02 1.11 1.13 1.04
endoribonuclease activity 19 1.25 1.08 1.3 1.22 1.37 1.23 -1.0
ribonuclease H activity 2 -1.13 1.13 1.07 1.39 1.3 -1.08 -1.14
ribonuclease III activity 4 1.01 1.12 1.7 -1.0 1.33 1.5 1.2
ribonuclease P activity 3 1.41 -1.04 -1.03 1.27 1.1 1.0 -1.33
exonuclease activity 33 1.16 1.17 1.21 1.21 1.29 1.11 1.04
exodeoxyribonuclease activity 7 -1.09 1.11 1.04 1.05 1.14 -1.05 -1.01
deoxyribonuclease II activity 1 3.57 -3.74 -3.12 -4.14 -2.27 -1.33 4.32
exoribonuclease activity 18 1.38 1.17 1.2 1.26 1.28 1.2 1.08
5'-3' exoribonuclease activity 2 -1.11 1.53 1.16 1.33 1.34 -1.11 1.19
poly(A)-specific ribonuclease activity 2 1.33 1.15 1.69 1.2 1.62 2.01 1.48
deoxyribonuclease activity 24 1.28 1.02 1.14 1.01 1.16 1.13 1.07
ribonuclease activity 41 1.37 1.11 1.23 1.22 1.32 1.27 1.04
tRNA-specific ribonuclease activity 4 1.4 1.02 -1.04 1.26 1.1 -1.04 -1.24
nucleoside diphosphate kinase activity 4 1.0 1.09 1.36 1.22 1.36 1.06 -1.14
nucleotide diphosphatase activity 2 1.11 1.19 1.38 1.17 1.36 1.15 -1.0
octanol dehydrogenase activity 1 1.29 1.1 1.03 1.22 1.29 1.66 -1.14
hydrolase activity, hydrolyzing O-glycosyl compounds 93 -1.83 -1.29 -2.4 -1.22 -1.47 -1.78 -1.26
alpha,alpha-trehalase activity 3 -2.73 1.23 -2.68 1.17 -1.22 -2.41 1.01
alpha-amylase activity 2 -34.84 -2.22 -3.89 2.13 -10.58 -52.06 -2.46
alpha-galactosidase activity 1 -4.17 1.11 -1.19 -1.11 -1.3 -2.49 3.87
alpha-glucosidase activity 13 -7.82 -1.11 -3.92 1.01 -2.19 -4.92 -2.34
alpha-mannosidase activity 9 -14.64 -1.14 -7.39 1.54 -1.15 -14.33 -25.61
alpha-L-fucosidase activity 1 -1.1 -1.19 -1.53 -1.9 -1.86 -1.28 7.99
alpha-N-acetylglucosaminidase activity 1 -1.03 -1.29 -2.28 -2.21 -1.93 20.24 3.19
beta-N-acetylhexosaminidase activity 4 2.6 -1.04 -1.38 1.02 1.14 -1.03 1.23
beta-galactosidase activity 2 -4.22 1.94 -2.65 -1.31 -2.65 -1.75 -2.68
beta-glucuronidase activity 2 -2.98 1.22 1.8 1.28 1.95 -1.65 1.15
beta-mannosidase activity 1 -5.95 1.18 1.25 1.37 1.4 -3.3 -1.02
chitinase activity 17 -1.5 -2.2 -3.34 -2.35 -1.62 1.11 2.06
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 5 1.56 1.24 -1.27 -1.11 -1.07 2.0 1.29
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity 2 2.21 -1.18 -1.12 1.09 -1.0 4.22 1.53
mannosyl-oligosaccharide glucosidase activity 1 1.11 1.54 -1.06 1.25 1.09 -1.47 1.06
oligo-1,6-glucosidase activity 1 -7.77 -4.97 -3.61 4.46 -5.62 -8.7 -6.61
oligosaccharyl transferase activity 5 -1.28 1.21 1.16 1.14 1.2 -1.13 1.35
dolichyl-diphosphooligosaccharide-protein glycotransferase activity 2 -2.3 1.16 -1.02 1.14 1.1 -1.42 1.33
dolichyl-phosphate beta-glucosyltransferase activity 1 -1.18 1.16 1.9 1.06 1.5 -1.14 1.68
dolichyl-phosphate beta-D-mannosyltransferase activity 1 1.01 1.25 1.35 1.09 1.77 -1.32 1.33
ornithine decarboxylase activity 2 -1.3 -1.56 -1.58 -1.19 -1.51 1.68 -1.8
ornithine-oxo-acid transaminase activity 2 -3.39 1.33 -4.62 1.16 1.17 -3.49 1.2
orotate phosphoribosyltransferase activity 1 1.61 1.06 1.09 1.15 1.38 -1.09 1.01
orotidine-5'-phosphate decarboxylase activity 1 1.61 1.06 1.09 1.15 1.38 -1.09 1.01
oxoglutarate dehydrogenase (succinyl-transferring) activity 2 -2.58 1.25 1.08 -1.04 1.34 -1.08 -1.45
pantothenate kinase activity 1 2.17 1.37 -1.41 1.23 1.4 -1.72 1.12
pantetheine-phosphate adenylyltransferase activity 1 -1.07 1.17 -1.47 1.46 1.3 -2.5 -1.32
peptide alpha-N-acetyltransferase activity 2 -1.32 1.41 1.74 1.19 1.16 -1.05 -1.05
peptide-aspartate beta-dioxygenase activity 1 1.22 -1.0 1.11 -1.0 1.04 1.19 -1.11
cyclosporin A binding 1 -1.56 1.12 -1.6 -1.09 -1.49 -1.56 -1.26
peroxidase activity 22 -1.07 -1.02 -1.12 -1.17 -1.19 -1.23 1.01
glutathione peroxidase activity 8 -1.36 1.09 -1.0 -1.35 -1.25 -2.14 1.1
phosphatidate cytidylyltransferase activity 1 3.07 1.1 2.07 -1.42 3.13 -1.11 1.4
phosphatidylserine decarboxylase activity 1 2.68 -1.15 1.36 1.05 1.26 2.6 1.26
phosphoacetylglucosamine mutase activity 1 -2.86 1.51 1.12 1.09 1.09 -5.18 1.1
phosphoenolpyruvate carboxykinase activity 2 -2.6 -1.77 1.37 -1.78 2.07 1.05 -1.67
phosphoenolpyruvate carboxykinase (GTP) activity 2 -2.6 -1.77 1.37 -1.78 2.07 1.05 -1.67
phosphoglucomutase activity 1 3.54 -1.2 -2.31 -1.28 -1.28 4.52 1.34
phosphomannomutase activity 3 -1.23 -1.01 1.33 1.13 1.42 -1.37 1.13
phosphogluconate dehydrogenase (decarboxylating) activity 4 1.7 1.24 -1.62 -1.03 -1.05 1.36 1.59
phosphoglycerate dehydrogenase activity 2 2.82 -1.08 -1.11 1.42 -1.05 1.77 -1.02
phosphoglycerate kinase activity 2 1.52 -1.04 -1.22 1.01 -1.05 1.8 -1.0
phosphoglycerate mutase activity 4 1.53 -1.02 -1.23 -1.07 -1.15 1.51 1.11
phospholipase activity 42 -2.02 -1.32 -1.4 -1.24 -1.44 -1.94 -1.19
lysophospholipase activity 5 -1.5 -1.08 -1.31 -1.5 -1.48 1.02 1.77
phospholipase A2 activity 10 1.72 -1.05 -1.16 -1.1 -1.05 -1.02 1.07
extracellular region 527 -1.12 -1.32 -1.37 -1.26 -1.26 -1.16 1.03
calcium-dependent phospholipase A2 activity 1 -1.04 -1.03 -1.01 -1.13 -1.15 1.09 -1.0
cytosol 213 1.26 1.07 1.15 1.06 1.18 1.2 1.04
calcium-independent phospholipase A2 activity 2 1.71 1.33 1.36 1.12 1.41 1.4 1.33
phospholipase C activity 8 1.4 1.12 1.15 -1.01 -1.08 1.08 1.32
phosphomevalonate kinase activity 1 2.16 -1.1 1.03 -1.13 1.06 2.2 1.18
phosphopantothenate--cysteine ligase activity 1 -1.95 1.39 1.68 1.01 1.49 -1.24 1.08
phosphopantothenoylcysteine decarboxylase activity 1 3.72 -1.03 1.39 1.15 1.52 2.47 1.16
phosphopyruvate hydratase activity 1 1.97 1.06 -1.39 -1.17 -1.32 2.59 1.17
phosphoribosylamine-glycine ligase activity 1 1.35 1.17 1.22 1.29 1.23 1.38 1.07
phosphoribosylaminoimidazole carboxylase activity 2 -1.17 -1.46 -1.46 -1.15 -1.17 1.65 -1.07
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity 2 -1.17 -1.46 -1.46 -1.15 -1.17 1.65 -1.07
phosphoribosylformylglycinamidine cyclo-ligase activity 1 1.35 1.17 1.22 1.29 1.23 1.38 1.07
phosphoribosylformylglycinamidine synthase activity 1 -1.91 1.54 -1.81 1.0 -1.5 -1.22 1.08
phosphoribosylaminoimidazolecarboxamide formyltransferase activity 1 -1.39 1.0 -1.49 -1.01 -1.06 1.63 -1.09
phosphoribosylglycinamide formyltransferase activity 1 1.35 1.17 1.22 1.29 1.23 1.38 1.07
phosphorylase activity 1 2.98 -1.08 1.5 -1.31 1.12 4.86 1.33
phosphoserine phosphatase activity 1 2.48 1.99 -2.53 -1.16 1.91 2.86 1.87
O-phospho-L-serine:2-oxoglutarate aminotransferase activity 1 2.63 -1.02 -1.9 1.11 -1.04 2.51 1.93
poly(ADP-ribose) glycohydrolase activity 1 1.16 1.03 1.19 1.34 1.67 -1.1 1.01
polynucleotide 5'-phosphatase activity 1 1.69 1.28 1.3 1.3 1.17 1.5 1.34
polynucleotide adenylyltransferase activity 6 1.11 1.12 1.2 1.08 1.07 1.17 1.11
polypeptide N-acetylgalactosaminyltransferase activity 14 -1.29 -1.23 -1.25 -1.28 -1.26 -1.61 1.75
polyribonucleotide nucleotidyltransferase activity 1 -1.12 1.21 1.17 1.13 1.3 1.14 -1.02
porphobilinogen synthase activity 1 -2.33 1.65 -1.72 1.07 -2.09 -1.28 -1.14
iron ion transport 7 1.59 -1.3 -1.22 -1.23 -1.14 1.5 1.12
procollagen-proline 4-dioxygenase activity 26 -1.01 -1.0 -1.08 -1.01 -1.13 -1.04 -1.05
proline dehydrogenase activity 1 2.07 -7.1 -4.47 -7.74 -3.15 31.25 -1.33
propionyl-CoA carboxylase activity 1 1.48 1.28 1.32 1.05 1.07 1.16 -1.01
prenyltransferase activity 12 -1.12 1.14 1.32 1.1 1.21 -1.16 1.28
protein farnesyltransferase activity 1 -1.83 -1.28 -1.22 1.05 -1.01 -1.04 2.75
protein geranylgeranyltransferase activity 6 -1.57 1.19 1.22 1.14 1.21 -1.62 1.21
CAAX-protein geranylgeranyltransferase activity 2 -2.28 1.15 1.11 1.06 1.05 -2.22 1.78
Rab geranylgeranyltransferase activity 4 -1.3 1.2 1.28 1.18 1.3 -1.38 -1.0
protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity 1 -2.13 1.18 1.09 1.41 1.8 -1.71 -1.76
protein kinase activity 255 1.18 1.11 1.27 1.06 1.27 1.34 1.17
protein histidine kinase activity 3 1.12 -1.13 1.03 -1.08 1.69 1.52 -1.14
protein serine/threonine kinase activity 183 1.12 1.13 1.33 1.08 1.3 1.3 1.15
transmembrane receptor protein serine/threonine kinase activity 5 -1.03 1.52 1.48 1.18 1.61 1.07 1.49
DNA-dependent protein kinase activity 1 1.33 1.54 1.93 1.1 1.72 1.13 1.74
AMP-activated protein kinase activity 3 1.06 1.32 1.11 1.03 -1.06 1.31 1.11
calmodulin-dependent protein kinase activity 8 2.03 1.07 1.21 1.02 1.3 2.02 1.5
elongation factor-2 kinase activity 2 1.62 1.17 1.62 -1.04 1.48 1.47 1.77
myosin light chain kinase activity 4 1.66 -1.14 1.36 -1.04 1.61 1.38 1.02
phosphorylase kinase activity 1 1.92 1.23 1.07 1.1 1.35 3.19 1.58
cyclic nucleotide-dependent protein kinase activity 6 -1.04 -1.05 1.23 -1.15 1.2 2.46 1.34
cAMP-dependent protein kinase activity 3 1.72 -1.04 1.4 -1.32 1.33 4.14 1.26
cGMP-dependent protein kinase activity 3 -1.85 -1.05 1.07 1.01 1.09 1.46 1.42
cyclin-dependent protein kinase activity 15 1.14 1.12 1.32 1.15 1.42 1.04 -1.02
protein kinase C activity 7 1.66 -1.04 1.77 -1.14 1.06 2.51 1.12
calcium-dependent protein kinase C activity 3 1.12 1.04 2.13 -1.07 1.01 3.21 -1.04
receptor signaling protein serine/threonine kinase activity 31 -1.19 1.17 1.44 1.1 1.38 1.04 1.15
G-protein coupled receptor kinase activity 3 1.16 1.4 1.53 1.09 1.29 1.52 1.29
JUN kinase activity 2 -1.09 1.03 1.52 1.15 1.41 -1.08 1.01
JUN kinase kinase kinase activity 2 1.23 1.27 1.56 1.2 1.54 1.23 1.3
MAP kinase activity 9 -1.46 1.12 1.25 1.14 1.35 -1.25 1.02
MAP kinase kinase activity 3 -1.23 1.23 1.34 1.19 1.4 1.25 1.23
MAP kinase kinase kinase activity 5 -1.39 1.21 1.48 1.15 1.82 1.09 1.04
MAPK/ERK kinase kinase activity 1 1.83 1.46 1.17 -1.02 1.24 1.79 1.33
ribosomal protein S6 kinase activity 1 -2.62 1.78 1.7 1.33 1.66 1.52 1.3
protein serine/threonine/tyrosine kinase activity 7 -1.0 1.17 1.32 1.17 1.33 1.18 1.15
protein tyrosine kinase activity 43 1.39 1.05 1.14 1.01 1.19 1.42 1.33
transmembrane receptor protein tyrosine kinase activity 21 1.55 -1.07 1.14 -1.01 1.13 1.58 1.42
non-membrane spanning protein tyrosine kinase activity 7 1.37 1.16 1.77 1.12 1.46 1.64 1.42
receptor signaling protein tyrosine kinase activity 3 -1.0 1.08 -1.13 -1.05 -1.16 -1.03 -1.05
protein-L-isoaspartate (D-aspartate) O-methyltransferase activity 1 2.93 1.03 1.2 1.19 1.05 1.97 1.02
protein-lysine 6-oxidase activity 2 -1.01 1.14 -1.1 1.01 -1.1 -1.06 -1.07
phosphoprotein phosphatase activity 86 1.24 1.12 1.24 1.06 1.2 1.31 1.16
protein serine/threonine phosphatase activity 42 1.25 1.09 1.29 1.04 1.19 1.37 1.15
calcium-dependent protein serine/threonine phosphatase activity 6 1.52 -1.02 1.2 1.05 1.13 1.24 1.06
protein tyrosine phosphatase activity 39 1.24 1.12 1.28 1.06 1.27 1.3 1.17
non-membrane spanning protein tyrosine phosphatase activity 5 1.49 1.12 1.2 1.1 1.4 1.22 1.1
prenylated protein tyrosine phosphatase activity 1 1.54 1.27 2.19 -1.23 1.74 3.0 1.51
receptor signaling protein tyrosine phosphatase activity 3 2.8 -1.06 1.33 -1.06 1.35 3.49 1.47
oxygen-dependent protoporphyrinogen oxidase activity 2 -1.11 1.24 1.36 1.38 1.3 1.17 -1.16
pseudouridylate synthase activity 3 1.57 1.31 1.17 1.55 1.45 1.03 1.08
purine-nucleoside phosphorylase activity 2 1.43 1.02 1.21 1.12 1.16 -1.08 1.07
pyridoxamine-phosphate oxidase activity 3 1.93 1.06 -1.17 1.32 1.07 1.07 -1.07
pyrimidodiazepine synthase activity 4 1.29 1.17 1.1 1.04 1.18 -1.03 1.04
pyrroline-5-carboxylate reductase activity 2 -1.77 1.27 -1.94 1.07 -1.03 -1.14 -1.01
pyruvate carboxylase activity 1 2.41 -1.07 -1.67 1.11 -2.11 1.65 1.08
pyruvate dehydrogenase activity 3 -1.02 1.01 1.31 1.1 -1.0 1.57 -1.25
pyruvate dehydrogenase (acetyl-transferring) activity 3 -1.02 1.01 1.31 1.1 -1.0 1.57 -1.25
pyruvate dehydrogenase (acetyl-transferring) kinase activity 1 1.67 -1.54 1.2 -1.13 7.02 3.44 1.09
[pyruvate dehydrogenase (lipoamide)] phosphatase activity 1 1.78 1.13 1.46 1.23 1.08 1.92 1.02
dihydrolipoyllysine-residue acetyltransferase activity 1 1.23 1.19 1.96 -1.07 1.35 3.33 1.11
pyruvate kinase activity 7 1.18 1.01 1.0 -1.0 -1.04 1.2 -1.0
retinal isomerase activity 1 1.12 -1.01 1.14 1.06 1.09 1.14 -1.06
retinol dehydrogenase activity 1 -1.07 1.02 1.03 -1.03 -1.28 1.11 -1.06
ribokinase activity 2 -1.21 1.07 -1.3 1.1 -1.27 -1.38 -1.12
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor 2 -2.27 -1.06 1.44 1.36 1.87 -1.61 -1.54
ribose phosphate diphosphokinase activity 2 2.41 1.04 1.7 -1.06 1.1 2.9 1.34
ribulose-phosphate 3-epimerase activity 1 3.69 1.12 -1.44 1.15 1.15 1.38 1.6
ribose-5-phosphate isomerase activity 1 2.8 1.42 -1.73 1.16 1.1 1.26 1.25
saccharopine dehydrogenase activity 1 1.21 1.36 -1.07 1.24 -1.06 1.55 1.4
saccharopine dehydrogenase (NAD+, L-lysine-forming) activity 1 1.21 1.36 -1.07 1.24 -1.06 1.55 1.4
selenide, water dikinase activity 2 1.76 1.25 1.23 1.04 1.04 1.62 -1.07
sepiapterin reductase activity 3 2.14 -1.76 -1.79 -1.65 -1.36 2.93 -1.29
serine C-palmitoyltransferase activity 2 -2.24 1.07 2.48 1.17 1.31 -1.71 -1.18
serine-pyruvate transaminase activity 1 1.1 -1.81 -2.08 -1.81 -1.6 3.21 -1.83
spermidine synthase activity 2 1.05 1.2 1.25 1.18 1.33 1.44 -1.0
sphingomyelin phosphodiesterase activity 5 -5.07 -3.51 -4.56 1.49 -1.12 -3.62 -4.08
stearoyl-CoA 9-desaturase activity 7 -1.4 1.15 -1.2 1.26 1.01 -1.67 -1.18
sterol esterase activity 1 -139.1 -18.6 -1.99 2.08 -24.32 -152.96 -197.4
sterol O-acyltransferase activity 3 -2.3 -1.64 -1.24 1.46 1.26 -1.59 -2.16
succinate-CoA ligase activity 6 1.06 -1.06 1.08 -1.08 1.02 1.3 -1.31
succinate-CoA ligase (ADP-forming) activity 5 1.09 -1.04 1.18 -1.15 -1.09 1.43 -1.27
succinate-CoA ligase (GDP-forming) activity 3 1.16 -1.04 -1.07 -1.04 1.11 1.22 -1.42
succinate-semialdehyde dehydrogenase activity 1 -2.19 1.37 2.06 1.34 1.0 1.58 -1.11
sulfate adenylyltransferase activity 1 -2.63 1.06 1.41 1.07 1.11 -1.64 -1.02
sulfate adenylyltransferase (ATP) activity 1 -2.63 1.06 1.41 1.07 1.11 -1.64 -1.02
sulfinoalanine decarboxylase activity 1 -1.56 1.66 -7.28 1.14 -1.03 -3.47 1.18
superoxide dismutase activity 5 1.45 1.15 -1.15 1.12 -1.07 1.37 -1.06
thiamine diphosphokinase activity 2 -1.04 1.3 1.02 1.32 1.14 -1.17 -1.06
thioredoxin-disulfide reductase activity 2 -1.32 1.3 -1.35 1.1 1.1 -1.38 1.15
thiosulfate sulfurtransferase activity 1 1.15 -1.38 2.62 1.38 1.04 -1.42 -1.83
threonine aldolase activity 1 1.44 -1.1 -1.93 1.6 -1.06 1.8 -2.26
L-threonine ammonia-lyase activity 1 -3.81 -2.74 -2.14 -1.15 11.07 -1.69 -3.46
thymidine kinase activity 1 1.02 1.09 1.32 1.32 1.3 -1.29 -1.13
thymidylate kinase activity 1 1.27 1.13 1.91 1.21 1.41 -1.17 -1.08
thymidylate synthase activity 1 -1.63 -1.08 1.19 1.46 1.72 -2.2 -2.17
sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity 1 3.18 1.11 -3.27 1.02 -1.44 -1.1 1.46
transketolase activity 2 2.03 1.17 -1.56 1.02 1.12 1.44 1.62
transposase activity 1 1.07 -1.04 -1.16 1.02 1.48 -1.27 -1.22
trehalose-phosphatase activity 2 5.88 -2.14 -1.49 -1.62 1.02 4.6 1.12
triglyceride lipase activity 38 -3.83 -1.33 -1.88 -1.09 -1.77 -4.41 -2.22
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity 1 1.03 1.15 1.06 1.36 -1.06 -1.46 -1.19
tRNA (guanine-N2-)-methyltransferase activity 1 1.09 1.31 1.08 1.21 1.15 1.13 1.18
aminoacyl-tRNA ligase activity 40 -1.07 1.26 1.26 1.14 1.18 1.05 1.09
alanine-tRNA ligase activity 3 -1.05 1.37 1.07 1.17 1.09 1.18 1.07
arginine-tRNA ligase activity 3 1.35 1.15 1.32 1.15 1.24 1.15 1.05
aspartate-tRNA ligase activity 1 -1.97 1.61 1.28 -1.18 1.45 -1.88 1.38
asparagine-tRNA ligase activity 2 -1.04 1.15 1.12 1.09 1.19 -1.05 1.03
cysteine-tRNA ligase activity 2 -1.01 1.37 1.43 1.08 1.22 1.24 1.76
glutamate-tRNA ligase activity 3 -1.23 1.31 1.44 1.01 1.37 1.11 1.37
glutamine-tRNA ligase activity 1 1.03 1.27 1.03 1.21 1.05 1.24 1.09
glycine-tRNA ligase activity 3 1.01 1.17 1.37 1.21 1.21 1.27 -1.07
histidine-tRNA ligase activity 1 -1.32 1.37 -1.07 1.31 -1.14 -1.74 -1.19
isoleucine-tRNA ligase activity 2 1.35 1.22 1.54 1.02 1.38 1.61 1.38
leucine-tRNA ligase activity 2 -1.17 1.4 1.1 1.12 1.07 1.1 1.24
lysine-tRNA ligase activity 1 1.12 1.29 1.39 1.11 1.29 1.02 1.14
methionine-tRNA ligase activity 2 -1.59 1.18 1.28 1.38 1.17 -1.27 -1.03
phenylalanine-tRNA ligase activity 3 -1.16 1.27 1.38 1.24 1.13 -1.0 -1.14
proline-tRNA ligase activity 2 -1.08 1.19 1.31 1.06 1.32 1.47 1.15
serine-tRNA ligase activity 3 -1.3 1.34 1.25 1.17 1.28 -1.22 -1.0
threonine-tRNA ligase activity 2 -1.65 1.24 1.06 1.13 -1.08 -1.17 1.02
tryptophan-tRNA ligase activity 2 1.09 1.09 1.24 1.11 1.12 1.12 1.03
tyrosine-tRNA ligase activity 2 1.14 1.27 1.29 1.14 1.19 1.03 -1.04
valine-tRNA ligase activity 2 -1.62 1.31 1.29 1.15 1.04 -1.25 1.17
tryptophan 2,3-dioxygenase activity 1 1.33 -1.46 -1.36 -1.56 -1.39 2.84 -1.33
tubulin-tyrosine ligase activity 11 1.17 1.01 -1.01 1.04 -1.02 1.1 1.04
tyrosine decarboxylase activity 2 2.12 -1.17 -1.18 -1.17 1.11 1.9 -1.07
L-tyrosine:2-oxoglutarate aminotransferase activity 1 1.14 1.12 -1.09 -1.15 1.09 -1.15 -1.05
ubiquitin activating enzyme activity 3 1.07 1.19 1.42 1.25 1.55 1.31 1.05
ubiquitin-protein ligase activity 83 1.15 1.18 1.45 1.14 1.34 1.23 1.22
ubiquitin-specific protease activity 8 1.17 1.21 1.8 1.18 1.58 1.96 1.41
uracil DNA N-glycosylase activity 2 2.91 -1.23 -1.13 -1.34 1.04 2.88 1.17
uracil phosphoribosyltransferase activity 1 1.85 1.12 1.41 1.03 1.01 1.67 1.33
urate oxidase activity 1 3.87 -2.08 -2.11 -2.0 -1.26 -1.05 -1.64
uridine kinase activity 2 4.18 -1.72 1.72 -1.65 -1.27 3.76 1.43
uridine phosphorylase activity 3 -2.2 -1.73 1.35 -1.47 -1.37 -2.19 1.39
uroporphyrinogen-III synthase activity 2 1.15 -1.11 -1.12 1.02 -1.09 1.11 -1.25
uroporphyrinogen decarboxylase activity 1 2.27 -1.08 -1.25 1.43 1.04 1.18 1.26
xanthine dehydrogenase activity 2 1.25 1.78 -1.17 -1.32 -1.19 -1.3 1.66
xanthine oxidase activity 1 1.38 1.39 -1.09 1.59 1.39 -1.89 1.34
xylulokinase activity 2 1.23 1.04 -1.16 -1.08 1.26 1.41 1.22
enzyme inhibitor activity 101 1.28 -1.39 -1.39 -1.37 -1.17 1.33 1.03
protein kinase inhibitor activity 6 1.32 1.13 1.13 1.05 1.2 1.27 1.35
cyclin-dependent protein kinase inhibitor activity 2 1.97 -1.0 1.05 1.02 1.15 1.58 1.04
protein phosphatase inhibitor activity 7 1.59 -1.08 -1.01 -1.03 1.27 1.27 -1.01
protein serine/threonine phosphatase inhibitor activity 1 1.57 1.1 -1.11 1.22 1.13 -1.01 -1.25
endopeptidase inhibitor activity 73 1.41 -1.48 -1.45 -1.49 -1.3 1.51 1.04
serine-type endopeptidase inhibitor activity 58 1.2 -1.48 -1.57 -1.54 -1.37 1.38 -1.05
cysteine-type endopeptidase inhibitor activity 6 3.11 -1.78 -1.05 -1.54 -1.18 1.44 1.41
signal transducer activity 443 1.09 1.01 1.1 1.0 1.08 1.12 1.06
receptor activity 428 1.12 -1.03 1.04 -1.02 1.04 1.12 1.04
ecdysteroid hormone receptor activity 2 1.39 1.12 1.31 1.09 1.22 1.45 1.35
thyroid hormone receptor activity 2 -1.28 1.12 1.08 -1.12 -1.1 -1.03 -1.04
transmembrane signaling receptor activity 332 1.1 -1.02 1.05 -1.02 1.03 1.1 1.04
acetylcholine-activated cation-selective channel activity 9 -1.07 1.01 -1.02 -1.03 -1.09 -1.06 -1.03
GABA-A receptor activity 3 1.07 1.04 1.03 -1.04 -1.11 -1.02 -1.07
carbohydrate binding 166 -1.92 -1.36 -1.53 -1.23 -1.33 -1.85 -1.01
cytokine receptor activity 1 1.28 1.03 1.08 -1.21 -1.11 1.23 -1.01
boss receptor activity 1 2.09 -1.24 -1.34 -1.08 -1.33 -1.62 1.07
Wnt-activated receptor activity 5 1.17 1.03 1.52 -1.14 1.66 -1.04 1.31
Wnt receptor signaling pathway 56 1.24 1.03 1.2 -1.03 1.29 1.38 1.28
Wnt receptor signaling pathway, calcium modulating pathway 2 1.15 1.15 1.16 1.02 1.3 1.14 2.54
G-protein coupled receptor activity 168 1.06 -1.03 1.05 -1.02 1.01 1.02 -1.02
adrenergic receptor activity 2 -1.09 1.2 -1.08 -1.0 -1.18 -1.21 -1.07
bombesin receptor activity 2 1.03 1.12 1.37 -1.03 -1.15 1.42 1.13
calcitonin receptor activity 5 1.36 -1.25 1.11 -1.21 1.02 -1.07 1.56
cholecystokinin receptor activity 2 -1.2 -1.05 1.02 -1.05 -1.23 -1.25 -1.17
dopamine receptor activity 4 -1.05 1.04 -1.1 1.03 -1.07 -1.17 -1.14
G-protein coupled GABA receptor activity 4 -1.05 1.06 -1.02 1.01 -1.05 -1.07 -1.16
galanin receptor activity 1 -1.14 1.16 1.12 1.07 1.38 -1.13 1.15
gonadotropin-releasing hormone receptor activity 2 1.14 1.03 1.06 1.02 -1.01 -1.0 -1.03
ionotropic glutamate receptor activity 35 1.11 -1.01 1.02 -1.04 -1.06 -1.02 -1.03
alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 2 -1.07 -1.07 -1.18 -1.06 -1.13 -1.05 -1.13
N-methyl-D-aspartate selective glutamate receptor activity 5 -2.2 1.03 -1.01 -1.04 -1.02 -1.52 1.05
leukotriene receptor activity 1 1.34 1.16 1.19 1.06 1.04 1.4 -1.06
neuropeptide Y receptor activity 6 -1.12 -1.28 1.15 -1.08 1.23 2.07 -1.01
olfactory receptor activity 58 -1.05 1.02 -1.02 1.02 -1.07 -1.04 -1.08
opioid receptor activity 1 1.11 1.13 -1.05 1.1 1.01 1.15 1.06
octopamine receptor activity 6 1.21 1.06 1.02 1.02 1.02 1.0 1.01
serotonin receptor activity 3 1.27 -1.02 1.07 1.0 1.01 1.11 1.03
somatostatin receptor activity 2 -1.22 1.13 1.03 -1.13 -1.24 -1.37 -1.14
tachykinin receptor activity 6 -1.02 -1.12 1.07 -1.2 -1.05 1.79 1.44
vasopressin receptor activity 1 -1.03 1.09 1.19 1.15 1.1 -1.1