Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression

Mean expression enrichment by gut region

Filter out everything which GO terms when the expression scale ratio is comprised between -1.5 and 1.5 for all regions
GO term Number of genes Crop
/ Full gut		 R2
/ Full gut		 R3
/ Full gut		 R4
/ Full gut		 R5
/ Full gut		 Hindgut
/ Full gut		 Cardia/R1
/ Full gut
protein deneddylation 3 1.57 -1.01 1.18 1.14 1.14 1.07 -1.1
stress fiber 1 1.76 1.07 1.13 1.08 1.49 1.28 1.15
glycoprotein binding 1 3.21 -1.21 1.67 1.12 1.32 6.4 2.23
lymphocyte mediated immunity 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
renal sodium ion transport 1 -52.82 -1.7 -31.49 1.13 -9.63 16.55 -13.85
ferrochelatase activity 1 1.62 1.26 1.09 -1.07 1.01 1.21 1.32
nicotinamidase activity 1 -2.04 1.72 -1.29 1.07 1.25 4.26 2.23
lipoate biosynthetic process 2 1.65 1.07 1.42 1.08 1.12 2.67 -1.13
response to UV-B 1 1.85 -1.14 1.04 1.61 1.1 1.04 1.04
ectodermal cell differentiation 2 4.98 -1.19 1.75 -1.46 1.16 1.31 1.35
nuclear matrix 3 -1.0 1.28 1.38 1.16 1.24 1.52 1.32
ceramidase activity 2 -7.56 -2.15 -1.17 1.28 -1.14 -15.17 -6.93
acyl-CoA delta11-desaturase activity 1 -3.53 -3.34 -2.71 -4.29 -3.06 -2.31 4.71
cytokine binding 3 1.17 1.12 1.1 1.02 1.54 1.2 1.72
T-tubule 1 1.33 1.32 2.26 1.11 1.52 1.39 1.48
A band 9 1.95 -1.09 -1.15 -1.11 1.13 1.79 1.07
cleavage furrow 9 -1.04 1.09 1.57 1.01 1.45 1.33 1.15
ESCRT-0 complex 2 -1.75 1.13 2.24 1.06 1.39 1.34 1.26
ribosome localization 1 2.15 -1.01 1.44 1.25 1.44 1.28 1.21
protein localization in Golgi apparatus 10 -1.16 1.12 1.17 1.04 1.21 1.41 1.65
pupation 4 2.01 -1.05 1.24 -1.24 1.14 2.15 1.25
DNA dealkylation 1 1.12 -1.01 1.19 1.74 1.2 1.06 -1.09
AP-2 adaptor complex binding 1 1.51 1.33 2.01 1.25 1.81 2.91 1.9
DNA protection 1 1.02 -1.01 1.31 1.02 1.58 1.3 1.2
presynaptic membrane 8 -1.25 1.03 1.27 -1.02 1.34 1.8 1.18
main axon 2 -1.07 -1.38 -1.02 -1.09 1.18 3.54 1.59
actin nucleation 4 -2.38 1.35 1.23 1.09 1.22 -1.94 1.21
negative regulation of S phase of mitotic cell cycle 11 1.34 1.21 1.41 1.15 1.44 1.65 1.53
habituation 4 1.3 -1.01 1.62 1.18 1.4 1.83 1.26
actin crosslink formation 1 2.2 1.13 -1.01 1.18 1.16 -1.08 1.17
glycolipid binding 1 -2.99 1.35 -1.24 1.41 -1.1 -2.55 -1.06
catecholamine transport 2 3.07 -1.44 -1.47 -1.28 -1.45 -1.2 -1.42
carboxylic ester hydrolase activity 99 -1.69 -1.12 -1.47 -1.07 -1.31 -2.03 -1.33
foraging behavior 1 -12.04 -1.69 9.34 -2.59 -11.09 -12.8 -6.11
regulation of canonical Wnt receptor signaling pathway 6 1.19 1.08 1.68 1.07 1.07 1.06 1.46
establishment of blood-brain barrier 19 2.5 -1.26 1.24 -1.17 1.21 2.3 1.4
Wnt protein secretion 1 1.86 -1.05 2.03 1.04 1.26 2.03 1.19
RISC-loading complex 1 1.44 1.23 1.89 1.19 2.25 1.64 1.56
cellular response to ecdysone 11 1.32 1.19 1.43 1.13 1.47 1.53 1.33
regulation of ion homeostasis 3 1.14 1.14 1.39 1.16 1.04 1.71 1.47
protein thiol-disulfide exchange 1 -1.26 1.49 1.56 1.08 1.23 -1.31 1.33
alpha-1,6-mannosyltransferase activity 1 1.2 1.3 1.28 1.05 1.27 1.14 1.6
trans-hexaprenyltranstransferase activity 2 2.38 1.18 1.12 1.03 1.43 1.86 1.15
phosphopyruvate hydratase complex 1 1.97 1.06 -1.39 -1.17 -1.32 2.59 1.17
alpha-glucoside transport 2 1.24 -2.16 -1.19 -2.0 -1.13 3.38 1.3
regulation of DNA recombination 2 -1.59 1.15 1.13 1.19 1.42 -1.74 -1.31
regulation of mitotic recombination 1 -2.02 1.1 1.06 1.2 1.9 -2.66 -1.77
negative regulation of mitotic recombination 1 -2.02 1.1 1.06 1.2 1.9 -2.66 -1.77
alpha-1,2-mannosyltransferase activity 1 -1.58 1.15 -1.08 1.11 -1.2 -1.77 1.49
acyl carrier activity 6 1.59 1.03 1.12 1.01 1.14 1.4 1.17
very long-chain fatty acid metabolic process 5 3.63 -2.39 -2.2 -3.1 -1.91 -1.08 3.71
long-chain fatty acid transporter activity 7 -2.15 1.3 -1.32 -1.52 -2.35 -1.39 -1.5
protein targeting to Golgi 10 -1.16 1.12 1.17 1.04 1.21 1.41 1.65
autophagic vacuole fusion 2 1.14 1.16 1.85 1.13 1.26 1.5 1.09
urea cycle 1 -31.89 1.77 -20.72 1.41 1.0 -12.66 -3.5
argininosuccinate metabolic process 1 -31.89 1.77 -20.72 1.41 1.0 -12.66 -3.5
ribosomal subunit export from nucleus 1 2.15 -1.01 1.44 1.25 1.44 1.28 1.21
ribosomal large subunit export from nucleus 1 2.15 -1.01 1.44 1.25 1.44 1.28 1.21
protein import into nucleus, docking 2 -1.85 1.21 1.23 1.37 1.53 -1.37 -1.23
protein import into nucleus, translocation 2 1.98 -1.11 1.05 1.22 1.33 2.03 -1.05
fatty-acyl-CoA binding 8 -2.25 -1.27 -1.85 1.18 1.35 -2.52 -1.44
L-ornithine transmembrane transporter activity 1 1.32 1.45 -1.5 1.71 1.05 1.03 -1.1
mitochondrial ornithine transport 1 1.32 1.45 -1.5 1.71 1.05 1.03 -1.1
M phase specific microtubule process 1 1.59 1.65 -1.13 1.13 1.0 -1.46 -1.04
G1 phase of mitotic cell cycle 1 -1.2 1.72 1.55 1.31 1.53 1.21 1.72
G1/S transition of mitotic cell cycle 14 1.35 1.24 1.43 1.21 1.54 1.24 1.25
regulation of transcription involved in G1/S phase of mitotic cell cycle 1 1.31 1.43 1.45 1.16 1.14 1.54 1.46
G2 phase of mitotic cell cycle 1 1.67 1.26 1.32 1.4 1.23 1.13 1.21
mitotic anaphase B 2 1.04 1.25 1.4 1.16 1.52 -1.16 1.12
mitotic telophase 1 1.4 1.02 1.15 1.14 1.72 -1.18 -1.16
sulfur amino acid biosynthetic process 3 1.32 1.11 1.04 -1.09 -1.92 1.19 1.3
sulfur amino acid transmembrane transporter activity 1 -7.18 -1.45 -9.47 1.62 3.49 -2.41 -5.84
sulfur amino acid transport 1 -7.18 -1.45 -9.47 1.62 3.49 -2.41 -5.84
sulfate assimilation 1 -2.63 1.06 1.41 1.07 1.11 -1.64 -1.02
nucleotide-excision repair complex 3 1.73 1.2 1.21 1.15 1.32 1.1 -1.16
regulation of transcription involved in G2/M-phase of mitotic cell cycle 1 1.12 1.4 1.69 -1.0 1.67 1.7 1.71
transcription factor TFIIIB complex 2 1.19 1.29 1.5 1.13 1.51 1.31 1.18
establishment of mitotic spindle orientation 2 1.02 1.4 1.82 1.21 1.49 1.4 1.34
Golgi cis cisterna 1 -1.12 1.19 1.36 1.12 1.23 -1.28 1.74
Golgi trans cisterna 2 -1.03 1.16 1.1 1.38 1.81 1.12 1.1
microfilament motor activity 3 6.28 -1.75 1.12 -1.66 1.09 3.74 -1.21
cytoplasmic ubiquitin ligase complex 1 2.69 1.18 1.72 1.15 -1.01 -1.18 -1.08
rRNA modification 5 1.57 1.18 1.26 1.33 1.41 1.18 -1.02
two-component sensor activity 3 1.12 -1.13 1.03 -1.08 1.69 1.52 -1.14
two-component response regulator activity 1 -1.1 1.39 1.36 1.05 1.38 3.53 1.68
protein phosphatase type 2A complex 8 1.09 1.04 1.37 1.07 1.23 2.15 1.1
two-component signal transduction system (phosphorelay) 3 -1.1 1.14 1.08 -1.02 -1.02 1.53 1.01
protein phosphatase type 1 complex 5 1.43 1.05 1.28 1.01 1.16 1.5 1.4
ribonuclease MRP complex 1 1.84 1.03 1.1 1.42 1.17 1.05 -1.14
rRNA (adenine-N6,N6-)-dimethyltransferase activity 2 1.61 1.27 1.44 1.22 1.57 1.46 1.13
rDNA binding 2 -1.04 1.15 1.82 1.29 2.02 1.26 1.15
activation of MAPK activity 7 1.11 1.21 1.54 1.12 1.37 2.0 1.14
inactivation of MAPK activity 1 2.84 1.44 1.69 1.19 1.68 4.37 1.83
MAPK import into nucleus 1 1.14 1.19 1.6 1.04 1.48 1.45 1.57
protein ubiquitination involved in ubiquitin-dependent protein catabolic process 5 1.02 1.13 2.15 1.07 1.56 1.16 1.11
vacuolar proton-transporting V-type ATPase, V0 domain 13 -2.32 -1.03 1.35 -1.29 -1.38 1.02 -1.29
vacuolar proton-transporting V-type ATPase, V1 domain 12 -1.17 1.02 1.44 -1.12 -1.04 1.8 -1.01
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity 1 -1.09 1.27 1.39 1.28 1.54 -1.1 1.18
cytoplasmic chromosome 1 1.18 1.16 1.75 1.38 1.68 1.06 -1.24
mitotic prometaphase 1 -1.39 -1.16 -1.07 1.34 1.62 -1.16 -1.17
C-4 methylsterol oxidase activity 2 -1.31 -6.89 -7.44 -1.07 -3.2 -1.65 -1.68
allantoin metabolic process 2 3.32 -1.45 -1.35 -1.39 -1.17 1.29 -1.34
allantoin catabolic process 1 2.85 -1.01 1.16 1.03 -1.08 1.74 -1.1
sodium:amino acid symporter activity 5 1.26 1.14 -2.06 -1.96 -1.76 -1.26 1.36
nucleoside transmembrane transporter activity 6 -1.51 1.3 -1.37 1.14 -1.09 -1.36 -1.05
proton-transporting ATPase activity, rotational mechanism 21 1.15 -1.01 1.22 -1.1 -1.03 1.64 -1.08
mitochondrial chromosome 1 1.18 1.16 1.75 1.38 1.68 1.06 -1.24
mitochondrial fission 2 1.47 -1.03 1.65 1.15 1.07 1.58 -1.11
peptidoglycan metabolic process 12 -1.13 -1.64 -1.19 -1.04 -1.82 -1.69 -1.29
polysaccharide biosynthetic process 22 1.55 1.02 -1.01 1.03 1.12 1.58 1.25
polysaccharide catabolic process 30 -1.17 -1.91 -2.09 -1.67 -1.68 -1.04 1.4
mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) 8 1.58 -1.08 1.12 -1.1 1.01 1.92 -1.31
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) 9 1.19 1.04 1.31 1.01 1.22 1.62 -1.14
1-phosphatidylinositol-3-phosphate 5-kinase activity 1 -1.33 1.29 1.91 1.33 2.36 1.28 1.16
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 10 1.48 1.17 1.74 1.19 1.61 1.9 1.56
nuclear-transcribed mRNA poly(A) tail shortening 7 1.62 1.13 1.74 1.15 1.59 2.05 1.42
deadenylation-dependent decapping of nuclear-transcribed mRNA 2 1.27 1.29 1.78 1.53 1.51 1.59 1.46
nuclear-transcribed mRNA catabolic process, exonucleolytic 1 -1.45 1.76 1.14 1.42 1.29 -1.3 1.32
integral to membrane of membrane fraction 2 1.74 1.04 1.6 1.07 1.43 2.77 1.46
retrograde transport, vesicle recycling within Golgi 10 -1.16 1.12 1.17 1.04 1.21 1.41 1.65
response to superoxide 2 1.69 1.17 1.01 1.09 1.11 1.41 -1.08
response to oxygen radical 2 1.69 1.17 1.01 1.09 1.11 1.41 -1.08
nicotinamide-nucleotide adenylyltransferase activity 1 -2.52 1.99 1.32 1.32 1.09 -1.34 1.43
organellar ribosome 72 1.04 1.07 1.23 1.29 1.25 1.45 -1.55
organellar large ribosomal subunit 44 1.03 1.05 1.24 1.3 1.28 1.46 -1.6
protein-methionine-R-oxide reductase activity 1 2.04 1.02 -1.15 -1.19 -1.3 1.08 -1.25
lytic vacuole 28 -2.58 -1.1 -2.35 1.15 -1.08 -2.06 -3.03
alternative nuclear mRNA splicing, via spliceosome 1 1.52 1.27 1.61 1.3 1.51 2.77 1.58
spliceosomal complex disassembly 1 1.69 1.29 1.56 1.32 1.6 1.63 1.44
RNA splicing, via endonucleolytic cleavage and ligation 3 1.93 1.15 1.42 1.2 1.36 1.44 1.34
four-way junction DNA binding 1 -1.12 1.35 2.36 1.33 2.9 1.28 1.43
mitochondrion degradation 1 2.65 1.08 1.15 1.38 1.25 2.74 1.17
maturation of 2S rRNA 1 1.7 -1.05 -1.07 -1.09 -1.18 1.33 1.14
oxidized base lesion DNA N-glycosylase activity 3 2.16 -1.01 1.16 1.13 1.13 1.51 -1.03
oxidized pyrimidine base lesion DNA N-glycosylase activity 1 3.75 1.0 1.19 1.14 1.11 1.95 1.06
meiotic mismatch repair 1 1.34 1.15 1.36 1.37 1.61 1.16 1.18
nucleotide-excision repair, DNA damage recognition 1 1.35 1.22 1.6 1.15 1.67 2.6 1.56
DNA catabolic process, endonucleolytic 4 1.64 1.12 1.39 1.15 1.35 1.4 1.54
DNA catabolic process, exonucleolytic 2 -1.31 1.21 1.11 1.22 1.62 -1.59 -1.29
nuclear chromosome, telomeric region 2 1.89 1.01 1.39 1.11 1.79 1.05 1.11
X chromosome 6 1.37 1.23 1.41 1.11 1.23 1.51 1.37
GINS complex 2 1.77 1.11 1.3 1.14 1.18 1.14 -1.06
inositol-1,4,5-trisphosphate 6-kinase activity 1 -1.15 1.56 -1.07 1.07 -1.15 -1.25 1.09
inositol hexakisphosphate kinase activity 1 -1.38 1.16 2.02 -1.07 2.12 1.33 1.59
translation repressor activity, nucleic acid binding 6 1.94 1.04 2.03 1.04 1.61 1.46 1.82
gamma-tubulin complex 8 1.55 1.01 1.26 1.07 1.31 1.48 1.15
gamma-tubulin large complex 5 1.67 -1.04 1.23 1.09 1.31 1.41 1.1
cytoplasmic mRNA processing body 13 1.31 1.27 1.6 1.18 1.51 1.59 1.3
mitochondrial RNA metabolic process 3 1.29 1.23 1.41 1.12 1.47 1.73 -1.1
RNA polymerase II core promoter proximal region sequence-specific DNA binding 4 1.25 1.09 1.19 1.0 1.33 1.57 1.45
RNA polymerase II basal transcription factor binding transcription factor activity 6 1.58 1.1 1.46 1.16 1.41 1.29 1.2
TFIIA-class transcription factor binding 3 1.34 1.29 1.39 1.2 1.61 1.37 1.28
TFIIF-class transcription factor binding 2 1.1 1.32 1.52 1.2 1.24 1.14 1.45
RNA polymerase II activating transcription factor binding 4 2.11 -1.73 -1.85 -1.26 -1.03 1.44 1.34
RNA polymerase II transcription coactivator activity 8 1.57 -1.19 -1.01 1.03 1.27 1.49 1.13
RNA polymerase II transcription corepressor activity 2 1.12 1.2 1.26 1.29 1.7 1.19 1.25
RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly 2 1.66 -1.04 1.36 1.21 1.19 1.16 -1.0
TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly 6 1.58 1.1 1.46 1.16 1.41 1.29 1.2
TBP-class protein binding RNA polymerase II transcription factor activity 6 1.58 1.1 1.46 1.16 1.41 1.29 1.2
DNA-dependent transcriptional start site selection 1 2.19 1.23 -1.08 1.33 1.17 -1.1 1.1
transcriptional start site selection at RNA polymerase II promoter 1 2.19 1.23 -1.08 1.33 1.17 -1.1 1.1
RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription 8 1.57 -1.19 -1.01 1.03 1.27 1.49 1.13
entry into host 2 1.04 1.05 1.19 -1.29 -1.39 2.64 1.17
neurotransmitter uptake 1 -1.06 -1.11 -1.0 -1.08 -1.15 3.37 -1.04
acetylcholine catabolic process in synaptic cleft 1 2.27 1.23 -5.17 -1.59 -2.2 -9.9 9.42
regulation of action potential 8 1.57 -1.04 1.3 -1.12 1.17 2.65 1.29
RNA methylation 10 1.62 1.18 1.23 1.26 1.35 1.29 1.02
selenocysteine incorporation 1 1.74 1.02 1.02 1.41 1.48 -1.49 -1.06
peptide amidation 1 2.74 1.3 1.75 1.08 1.98 1.97 2.28
lipopolysaccharide binding 1 8.83 -1.7 -1.73 -1.63 -1.34 3.89 1.3
ovarian follicle development 1 -1.49 2.58 -1.26 -1.23 -1.23 -1.38 1.24
oocyte growth 2 1.25 1.36 1.54 1.22 1.6 1.07 1.72
regulation of cell growth 38 1.09 1.19 1.46 1.1 1.43 1.53 1.25
galactoside binding 2 1.45 -1.07 1.88 1.03 1.06 1.31 1.14
detection of chemical stimulus involved in sensory perception of bitter taste 1 -1.77 -1.51 -1.46 -1.66 9.03 1.38 -1.43
detection of chemical stimulus involved in sensory perception of sweet taste 1 15.43 1.05 -1.1 -1.34 2.06 11.73 3.15
dense fibrillar component 1 -1.19 1.16 -1.05 1.68 1.27 -1.6 -1.28
conditioned taste aversion 3 1.58 1.48 1.62 -1.13 1.26 1.28 1.57
ameboidal cell migration 35 1.62 -1.01 1.31 -1.06 1.21 1.46 1.11
acrosomal vesicle 1 -1.22 1.14 1.06 1.01 -1.52 -1.37 1.04
ATPase activator activity 3 1.77 1.07 1.2 1.24 1.37 1.32 1.35
long-chain fatty acid metabolic process 8 2.31 -2.32 -1.73 -1.98 -1.14 -1.49 1.69
histamine metabolic process 2 1.02 -1.27 1.33 1.09 1.3 1.8 1.14
histamine biosynthetic process 1 -1.31 -1.76 1.72 1.22 1.97 3.11 1.28
formation of primary germ layer 28 1.53 -1.01 1.18 -1.09 1.11 1.67 1.15
ectoderm formation 2 4.98 -1.19 1.75 -1.46 1.16 1.31 1.35
endoderm formation 4 2.13 -1.15 1.08 -1.19 1.07 2.11 1.76
mesoderm formation 26 1.41 1.01 1.15 -1.07 1.1 1.6 1.11
endodermal cell fate commitment 1 8.12 -1.58 1.44 -1.54 1.01 1.69 1.21
ectodermal cell fate commitment 2 4.98 -1.19 1.75 -1.46 1.16 1.31 1.35
ectodermal cell fate specification 2 4.98 -1.19 1.75 -1.46 1.16 1.31 1.35
ruffle 2 1.28 1.39 2.24 -1.02 2.03 1.81 1.72
lipid kinase activity 2 1.57 1.08 1.68 -1.01 1.59 1.77 1.96
ceramide kinase activity 1 2.79 -1.02 1.66 -1.11 1.24 2.25 2.21
establishment of imaginal disc-derived wing hair orientation 22 1.56 1.08 1.28 1.02 1.4 1.32 1.3
neuron migration 1 -1.42 1.01 1.2 1.29 2.44 -1.59 1.35
kidney development 3 -1.1 -1.05 -1.04 -1.15 -1.04 1.01 1.54
pattern binding 116 -1.88 -1.54 -1.66 -1.39 -1.53 -1.88 1.19
response to yeast 1 5.18 -1.34 1.33 -1.5 1.33 6.7 1.77
nucleoside binding 5 -2.97 1.34 -1.45 1.07 -1.17 -2.3 -1.24
endothelial cell development 3 1.7 1.01 1.41 -1.21 1.32 4.52 2.14
selenium compound metabolic process 2 1.76 1.25 1.23 1.04 1.04 1.62 -1.07
tissue homeostasis 20 1.33 -1.02 1.13 -1.12 1.22 1.46 1.54
negative regulation of protein phosphorylation 2 -1.04 1.11 1.79 -1.0 1.29 1.24 1.01
positive regulation of protein phosphorylation 5 1.08 1.17 1.78 1.11 1.35 1.9 1.34
regulation of cell-matrix adhesion 2 1.91 1.0 2.08 1.07 1.96 1.63 1.31
negative regulation of cell-matrix adhesion 1 2.96 1.13 1.75 -1.2 1.98 1.94 1.75
startle response 13 1.09 1.15 1.46 1.07 1.52 1.19 1.26
G-protein alpha-subunit binding 2 -1.16 1.18 -1.02 1.16 1.01 -1.6 -1.07
morphogenesis of an epithelial sheet 1 1.57 1.36 1.53 1.09 1.59 1.28 1.35
regulation of heart rate 3 -2.33 1.98 1.4 -1.73 -1.39 2.29 -1.17
p53 binding 1 1.78 1.16 2.67 1.12 2.53 3.19 2.15
epithelial cell development 14 1.16 1.1 1.33 1.01 1.23 1.71 1.39
protein depalmitoylation 2 2.75 1.12 1.29 1.19 1.61 1.16 1.22
regulation of receptor internalization 2 2.64 -1.34 1.04 -1.28 -1.11 2.63 1.36
positive regulation of receptor internalization 2 2.64 -1.34 1.04 -1.28 -1.11 2.63 1.36
polyprenyltransferase activity 1 1.04 1.26 1.1 1.28 -1.02 -1.97 -1.12
tRNA wobble base modification 2 1.94 1.19 1.23 1.17 1.27 1.92 1.12
tRNA wobble uridine modification 2 1.94 1.19 1.23 1.17 1.27 1.92 1.12
podosome 1 -1.23 -1.76 -1.82 -1.76 -2.16 17.9 -1.88
store-operated calcium entry 1 2.66 -1.14 1.6 1.07 1.44 4.2 2.14
aggressive behavior 44 1.19 1.05 1.23 -1.02 1.15 1.61 1.24
inter-male aggressive behavior 42 1.18 1.06 1.2 1.0 1.15 1.58 1.25
G-quadruplex RNA binding 1 1.1 1.52 1.31 1.18 1.34 1.42 1.38
palmitoyltransferase complex 1 -1.92 1.11 2.34 1.27 1.64 -1.44 -1.26
defense response to insect 1 23.01 -3.14 -2.9 -3.17 -2.48 1.73 2.58
positive regulation of antimicrobial peptide production 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
innate immune response in mucosa 1 -1.37 -1.13 -1.19 -1.54 1.82 7.35 2.8
response to molecule of bacterial origin 3 2.15 1.03 1.06 -1.04 1.33 1.63 1.06
adaptive immune response 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
organ or tissue specific immune response 7 1.24 1.06 1.29 -1.06 1.56 1.62 1.43
immune effector process 20 1.79 -1.15 1.28 -1.11 1.26 1.41 1.26
activation of immune response 1 1.17 1.46 1.63 1.36 1.42 1.78 1.19
myeloid leukocyte activation 1 2.18 -2.11 2.19 1.49 1.48 1.37 1.38
mucosal immune response 7 1.24 1.06 1.29 -1.06 1.56 1.62 1.43
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 3 1.28 -1.17 2.05 1.18 1.64 1.24 1.18
inflammatory response to antigenic stimulus 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
acute inflammatory response to antigenic stimulus 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
production of molecular mediator of immune response 2 -1.54 1.11 1.81 1.12 1.7 3.17 1.43
leukocyte mediated immunity 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
hypersensitivity 2 -2.37 1.1 1.16 -1.04 1.34 -1.89 1.24
positive regulation of immune system process 8 1.43 1.03 1.15 1.01 1.19 1.8 1.48
positive regulation of immune effector process 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
positive regulation of production of molecular mediator of immune response 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
antimicrobial peptide production 2 -1.54 1.11 1.81 1.12 1.7 3.17 1.43
antifungal peptide production 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
regulation of antifungal peptide production 7 2.0 -1.32 -1.17 1.03 1.03 1.92 1.18
peptide secretion 1 1.36 -1.09 1.47 1.03 1.67 -1.23 2.47
positive regulation of antifungal peptide production 1 -1.72 1.19 -1.18 1.31 1.64 3.16 1.11
negative regulation of antimicrobial peptide biosynthetic process 2 1.03 1.14 1.57 1.07 1.57 -1.03 -1.32
positive regulation of antimicrobial peptide biosynthetic process 23 1.75 -1.22 -1.09 -1.11 -1.01 1.39 1.29
negative regulation of antibacterial peptide biosynthetic process 2 1.03 1.14 1.57 1.07 1.57 -1.03 -1.32
regulation of antifungal peptide biosynthetic process 6 2.45 -1.42 -1.16 -1.01 -1.05 1.77 1.2
regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria 7 1.96 -1.11 1.11 -1.19 1.09 1.65 1.22
negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria 2 1.03 1.14 1.57 1.07 1.57 -1.03 -1.32
regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria 4 1.05 -1.9 -2.24 -1.85 -1.9 -1.18 1.68
negative regulation of response to biotic stimulus 7 1.37 1.0 1.62 1.21 1.38 -1.12 -1.13
positive regulation of response to biotic stimulus 1 8.35 -1.25 -1.3 -1.07 -1.15 1.62 -1.07
negative regulation of humoral immune response 4 1.35 1.1 1.46 1.15 1.8 1.12 1.2
skeletal muscle contraction 2 -1.89 -1.52 -1.42 -1.43 -1.62 -1.61 2.67
renal system process 6 -4.46 1.18 -1.92 -1.14 -3.52 -1.44 -1.93
negative regulation of heart induction by canonical Wnt receptor signaling pathway 3 1.09 1.1 1.13 1.08 1.18 1.14 2.09
outflow tract morphogenesis 3 -1.03 1.08 1.55 1.17 2.15 1.03 1.48
regulation of organ formation 8 1.56 -1.2 -1.1 1.04 1.14 1.2 -1.02
endothelium development 3 1.7 1.01 1.41 -1.21 1.32 4.52 2.14
Wnt receptor signaling pathway involved in heart development 3 1.09 1.1 1.13 1.08 1.18 1.14 2.09
amino acid transmembrane transport 30 -1.61 -1.12 -1.51 -1.16 -1.02 -1.08 -1.1
apical constriction 4 -1.26 1.28 1.59 1.06 1.39 1.15 1.23
cytoneme morphogenesis 2 -1.85 -1.12 1.68 1.29 1.66 1.71 -2.53
neural retina development 1 -1.1 -1.15 -1.07 -1.18 1.52 1.28 1.24
bent DNA binding 2 1.7 1.14 1.37 1.1 1.36 1.18 1.22
lamin binding 1 1.4 1.14 1.18 1.58 1.38 1.2 1.19
satellite DNA binding 5 1.25 1.13 1.51 1.21 1.5 1.17 1.18
termination of RNA polymerase II transcription 1 -1.51 -1.02 1.38 1.04 1.42 1.11 -1.1
cytoplasmic sequestering of transcription factor 4 2.74 1.08 1.33 1.02 1.2 2.19 1.75
double-stranded RNA binding 16 1.33 -1.04 1.19 -1.13 1.16 1.42 1.51
double-stranded RNA adenosine deaminase activity 1 1.13 1.14 1.55 1.01 1.4 2.0 1.26
mRNA 3'-UTR binding 17 1.34 1.14 1.46 1.02 1.31 1.89 1.29
response to unfolded protein 2 1.04 1.38 1.16 -1.1 1.05 1.03 1.56
contractile fiber 33 2.45 -1.47 -1.08 -1.25 1.2 1.97 -1.14
actin filament bundle assembly 17 1.57 -1.02 1.24 -1.1 1.24 1.29 1.51
barbed-end actin filament capping 2 -1.38 -1.03 2.18 1.01 1.59 -1.39 -1.04
actin monomer binding 1 -3.23 -1.14 1.86 -1.09 2.26 -4.44 -1.1
acute-phase response 1 1.84 1.22 1.59 1.61 1.65 1.41 1.04
lysozyme activity 14 1.98 -1.64 -2.07 -1.66 -1.61 -1.16 1.06
defense response to fungus 28 1.68 -1.27 -1.31 -1.29 -1.25 1.08 1.24
response to virus 12 2.35 -1.64 -1.09 -1.61 1.07 1.84 1.26
serine-type endopeptidase activity 263 -2.24 -1.42 -1.67 -1.14 -1.46 -2.32 -1.65
protein-glutamine gamma-glutamyltransferase activity 2 5.84 -1.94 -1.03 -1.59 -1.03 2.32 1.28
antigen binding 1 -1.71 -1.18 -1.3 -1.15 -1.23 -1.3 1.07
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 1 1.32 -4.96 -6.02 -4.98 -1.62 7.64 -3.94
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 1 3.18 1.02 1.47 1.11 1.44 4.09 2.36
beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity 1 3.39 -1.12 1.06 -1.11 1.06 1.27 -1.12
beta-alanyl-dopamine hydrolase activity 1 -1.31 -1.76 1.72 1.22 1.97 3.11 1.28
beta-ureidopropionase activity 1 17.28 -3.07 -1.83 -2.92 -2.4 3.32 1.6
gamma-glutamyltransferase activity 4 1.24 -1.34 -1.15 1.08 1.94 1.31 -1.06
1-acylglycerol-3-phosphate O-acyltransferase activity 6 -1.56 -1.19 -1.0 1.18 2.24 -2.62 -1.99
1-pyrroline-5-carboxylate dehydrogenase activity 3 1.56 -1.48 -1.15 -1.62 -1.43 2.14 1.15
1,3-beta-D-glucan synthase activity 1 12.72 -1.88 -1.16 -3.3 -1.54 3.13 2.87
1,4-alpha-glucan branching enzyme activity 1 3.55 -1.35 -1.97 1.08 1.09 1.58 1.19
1-alkyl-2-acetylglycerophosphocholine esterase activity 1 3.85 1.07 1.8 1.09 1.57 2.16 1.8
2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity 5 -4.34 1.01 1.27 1.24 1.5 -3.41 -1.26
3-beta-hydroxy-delta5-steroid dehydrogenase activity 1 7.52 -1.63 -1.52 -1.44 -1.48 2.76 1.78
3-hydroxyisobutyryl-CoA hydrolase activity 1 1.35 1.24 1.18 -1.16 -1.11 6.95 -1.22
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 2 1.67 1.29 1.69 -1.02 1.34 1.99 1.11
3-oxo-5-alpha-steroid 4-dehydrogenase activity 1 -1.31 1.28 -1.32 1.3 1.08 -2.32 -1.18
4-aminobutyrate transaminase activity 1 -1.88 3.07 -1.92 -1.52 -1.3 -2.05 1.06
4-hydroxyphenylpyruvate dioxygenase activity 1 1.86 -1.07 1.21 1.03 1.14 1.09 -1.06
5-aminolevulinate synthase activity 1 1.58 1.36 -1.31 -1.09 -1.26 1.25 1.23
6-phosphofructokinase activity 1 2.63 -1.22 -1.22 1.02 -1.12 5.11 1.3
6-phosphofructo-2-kinase activity 1 1.09 -1.34 2.59 -1.04 1.14 3.38 -1.06
6-pyruvoyltetrahydropterin synthase activity 1 2.12 1.31 1.32 1.23 1.73 1.01 2.0
AMP deaminase activity 1 1.21 1.11 1.3 -1.14 1.24 3.4 1.06
protein C-terminal carboxyl O-methyltransferase activity 1 -2.13 1.18 1.09 1.41 1.8 -1.71 -1.76
CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity 1 2.1 -1.04 1.71 -1.1 1.9 -1.29 1.13
CDP-diacylglycerol-serine O-phosphatidyltransferase activity 1 1.61 1.37 2.22 1.0 1.13 1.67 1.83
D-amino-acid oxidase activity 2 -2.82 -1.69 -2.22 1.7 1.95 -1.63 -1.83
DNA-(apurinic or apyrimidinic site) lyase activity 5 1.72 -1.0 1.07 1.11 1.19 1.32 1.0
methylated-DNA-[protein]-cysteine S-methyltransferase activity 1 1.12 -1.01 1.19 1.74 1.2 1.06 -1.09
DNA ligase (ATP) activity 2 1.29 1.46 1.49 1.24 1.5 1.27 1.28
DNA topoisomerase (ATP-hydrolyzing) activity 3 -1.26 1.43 1.56 1.29 1.52 1.12 1.27
GMP synthase activity 1 1.14 1.09 1.34 -1.05 1.24 1.35 2.12
GMP synthase (glutamine-hydrolyzing) activity 1 1.14 1.09 1.34 -1.05 1.24 1.35 2.12
GPI-anchor transamidase activity 1 1.21 1.1 1.8 1.25 1.66 -1.16 1.35
synaptic vesicle uncoating 2 -1.44 1.22 1.71 1.06 1.91 1.53 1.42
GTP cyclohydrolase activity 1 33.5 -5.63 -5.79 -6.03 -4.58 -1.32 6.94
GTP cyclohydrolase I activity 1 33.5 -5.63 -5.79 -6.03 -4.58 -1.32 6.94
hydrogen ion transporting ATP synthase activity, rotational mechanism 16 1.35 -1.04 1.11 -1.09 -1.01 1.54 -1.13
IMP cyclohydrolase activity 1 -1.39 1.0 -1.49 -1.01 -1.06 1.63 -1.09
IMP dehydrogenase activity 1 1.16 1.34 1.12 1.03 1.08 -1.1 1.99
L-iditol 2-dehydrogenase activity 3 1.17 -1.39 -1.37 1.12 1.23 1.74 -1.02
L-iduronidase activity 1 -1.71 1.0 1.11 -1.04 1.62 -1.12 -1.27
N-acetylgalactosamine-4-sulfatase activity 4 1.55 -1.16 -1.4 1.09 1.42 2.61 -1.17
NAD+ ADP-ribosyltransferase activity 1 -2.18 1.38 1.41 1.1 1.13 -1.47 1.05
NAD+ synthase (glutamine-hydrolyzing) activity 1 2.07 1.6 1.04 1.19 1.4 2.13 1.77
NADH dehydrogenase activity 36 1.13 1.03 1.27 1.06 1.1 1.72 -1.29
NADPH-hemoprotein reductase activity 1 1.63 1.35 1.12 -1.0 1.2 -1.04 1.34
NADPH dehydrogenase activity 1 -1.51 1.45 1.08 1.06 -1.12 -1.58 -1.42
RNA-directed DNA polymerase activity 1 1.54 1.82 1.92 -1.04 1.87 1.15 2.39
UDP-N-acetylglucosamine diphosphorylase activity 1 -1.57 -1.13 1.65 -1.09 1.26 -1.83 1.72
UDP-glucose:glycoprotein glucosyltransferase activity 1 1.21 1.16 1.35 -1.04 1.59 1.69 2.54
acetate-CoA ligase activity 2 1.63 1.11 -1.36 -1.04 -1.71 1.16 1.18
acetyl-CoA C-acyltransferase activity 4 1.58 1.11 -1.25 1.12 1.08 1.06 -1.32
acetyl-CoA carboxylase activity 1 7.73 1.2 -1.41 -2.71 1.2 3.14 4.69
acetylcholinesterase activity 1 2.27 1.23 -5.17 -1.59 -2.2 -9.9 9.42
acid phosphatase activity 12 1.44 1.13 -1.05 -1.03 -1.02 1.81 1.28
aconitate hydratase activity 4 1.11 1.25 1.22 -1.14 -1.03 1.75 1.32
acyl-CoA dehydrogenase activity 15 -1.17 1.11 -1.37 1.1 1.1 -1.79 -1.3
acyl-CoA oxidase activity 6 -2.19 1.03 -1.7 1.08 1.14 -3.66 -1.47
acylphosphatase activity 6 1.57 1.0 -1.02 1.01 -1.1 1.04 -1.12
adenosine deaminase activity 8 -1.69 1.1 1.06 -1.03 -1.09 1.15 -1.16
cation-transporting ATPase activity 26 1.1 1.0 1.24 -1.08 1.02 1.51 -1.05
copper-exporting ATPase activity 1 -2.22 1.33 3.02 1.07 -1.16 -1.12 1.08
phospholipid-translocating ATPase activity 6 -2.65 1.11 -1.12 1.22 1.24 -1.33 -1.09
adenosylhomocysteinase activity 3 -2.93 -1.82 -1.21 -1.07 1.22 1.86 -1.16
adenosylmethionine decarboxylase activity 1 1.82 1.07 1.08 1.22 1.03 1.75 -1.05
adenylate kinase activity 6 1.61 -1.18 1.01 1.04 1.05 1.04 -1.33
adenylosuccinate synthase activity 1 2.08 1.19 1.56 -1.1 -1.15 1.56 -1.05
adenylylsulfate kinase activity 1 -2.63 1.06 1.41 1.07 1.11 -1.64 -1.02
L-alanine:2-oxoglutarate aminotransferase activity 1 -2.33 1.13 1.14 1.09 1.76 1.77 -1.09
alcohol dehydrogenase (NAD) activity 5 1.66 -1.09 -1.8 -1.39 -1.21 1.37 1.27
aldehyde dehydrogenase (NAD) activity 3 -1.65 1.15 -1.65 1.05 -1.41 -1.9 -1.31
aldehyde dehydrogenase [NAD(P)+] activity 1 1.67 -1.24 -1.26 1.36 2.03 -1.43 1.25
aldose 1-epimerase activity 3 -1.46 1.17 -1.47 -1.07 1.13 -1.58 -1.03
alkaline phosphatase activity 13 -5.32 -1.81 -4.2 -1.19 -1.19 -4.42 -4.05
allantoinase activity 1 2.85 -1.01 1.16 1.03 -1.08 1.74 -1.1
amidase activity 1 1.54 -1.32 2.9 1.39 -1.83 -6.19 -2.79
amidophosphoribosyltransferase activity 2 1.11 1.02 -1.15 -1.13 -1.43 1.89 -1.09
aminoacyl-tRNA hydrolase activity 3 1.72 -1.02 1.14 1.1 1.0 1.49 -1.08
aminoacylase activity 6 -1.72 -1.86 -1.07 -1.63 1.29 -1.6 -1.71
aminomethyltransferase activity 4 1.27 1.14 1.17 1.01 -1.01 1.6 1.08
nucleoside-diphosphatase activity 3 -2.29 1.44 -2.09 1.33 -1.38 -3.32 1.1
arginase activity 2 1.73 -1.09 1.02 -1.05 -1.18 2.27 1.17
argininosuccinate synthase activity 1 -31.89 1.77 -20.72 1.41 1.0 -12.66 -3.5
argininosuccinate lyase activity 1 -15.39 1.51 -7.96 1.39 1.15 -4.77 -1.11
arginyltransferase activity 1 1.03 1.39 1.46 1.24 1.37 1.69 1.36
aromatic-L-amino-acid decarboxylase activity 4 2.04 -1.66 -1.74 -1.59 -1.59 1.51 1.84
aralkylamine N-acetyltransferase activity 1 -8.98 1.77 -2.05 -1.02 -2.08 -14.22 1.22
arylamine N-acetyltransferase activity 1 -8.98 1.77 -2.05 -1.02 -2.08 -14.22 1.22
aryldialkylphosphatase activity 1 1.9 -1.44 -1.39 -2.02 1.17 21.38 -1.25
asparaginase activity 4 1.31 -1.05 -1.24 -1.15 1.04 1.97 1.03
L-aspartate:2-oxoglutarate aminotransferase activity 2 1.83 1.18 -1.32 -1.0 1.19 1.57 1.14
aspartate carbamoyltransferase activity 1 -1.12 1.14 1.63 1.21 1.33 1.0 1.05
biliverdin reductase activity 1 -1.51 1.45 1.08 1.06 -1.12 -1.58 -1.42
biotin carboxylase activity 3 2.88 1.25 -1.21 -1.16 -1.0 2.26 1.91
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity 1 -1.85 1.12 1.37 1.12 1.23 -1.02 1.02
branched-chain-amino-acid transaminase activity 1 5.21 1.63 1.44 -1.45 -2.46 1.42 2.6
carbamoyl-phosphate synthase (ammonia) activity 1 -1.12 1.14 1.63 1.21 1.33 1.0 1.05
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 1 -1.12 1.14 1.63 1.21 1.33 1.0 1.05
carbonyl reductase (NADPH) activity 3 1.57 1.0 -1.52 -1.25 -1.09 1.43 1.09
carnitine O-palmitoyltransferase activity 1 1.55 1.41 -1.09 1.13 1.34 -1.06 1.05
catalase activity 3 1.88 -1.66 -2.02 -1.59 -1.55 2.15 -1.21
catechol oxidase activity 1 1.73 1.33 1.02 1.13 -1.06 -1.05 1.06
chitin deacetylase activity 2 2.14 -1.13 1.05 -1.06 -1.29 -1.18 -1.25
chitin synthase activity 2 -4.74 1.25 1.37 -1.3 1.38 1.09 1.15
choline kinase activity 2 1.11 1.13 1.36 1.19 1.43 2.57 1.13
cholinesterase activity 2 -1.12 1.28 -2.63 -1.13 -1.28 -3.75 2.43
choline-phosphate cytidylyltransferase activity 2 1.06 -1.23 1.07 1.02 1.15 -1.4 1.55
coproporphyrinogen oxidase activity 1 -1.38 1.31 1.39 1.26 1.22 -1.88 -1.39
cyclic-nucleotide phosphodiesterase activity 8 1.68 1.07 1.28 1.01 1.26 2.25 1.48
3',5'-cyclic-nucleotide phosphodiesterase activity 8 1.68 1.07 1.28 1.01 1.26 2.25 1.48
3',5'-cyclic-AMP phosphodiesterase activity 4 1.06 1.26 1.31 1.05 1.3 1.79 1.4
cystathionine beta-synthase activity 1 1.25 1.1 1.48 -1.98 -7.11 -1.17 2.59
cytidine deaminase activity 3 -2.8 1.04 -1.39 1.2 1.32 -1.87 -1.06
cytosine deaminase activity 1 1.58 1.21 -1.04 1.33 -1.0 -1.93 1.34
dCMP deaminase activity 1 2.54 -1.17 -1.05 1.35 1.96 1.77 -1.1
glycogen debranching enzyme activity 1 1.91 -1.57 -1.98 1.36 -1.16 2.47 1.07
4-alpha-glucanotransferase activity 1 1.91 -1.57 -1.98 1.36 -1.16 2.47 1.07
amylo-alpha-1,6-glucosidase activity 1 1.91 -1.57 -1.98 1.36 -1.16 2.47 1.07
deoxyribose-phosphate aldolase activity 1 -1.52 1.52 -1.38 1.37 -1.06 -2.8 1.21
dephospho-CoA kinase activity 2 1.04 1.25 -1.2 1.45 1.19 -1.52 -1.32
diacylglycerol cholinephosphotransferase activity 1 -3.65 1.65 3.17 1.08 1.15 -2.09 2.51
diacylglycerol kinase activity 8 1.65 1.05 -1.03 -1.02 -1.04 1.17 1.24
diacylglycerol O-acyltransferase activity 1 -1.05 1.33 3.49 1.16 1.98 2.09 1.25
dihydrofolate reductase activity 1 2.25 -1.1 -1.03 1.28 1.09 2.14 -1.24
dihydrolipoamide branched chain acyltransferase activity 1 1.74 1.44 1.67 1.01 1.35 1.38 1.19
dihydrolipoyl dehydrogenase activity 1 -1.4 -1.14 2.27 -1.25 -1.48 1.94 -1.5
dihydrolipoyllysine-residue succinyltransferase activity 1 1.27 -1.02 1.79 -1.24 1.05 3.95 -1.37
dihydroorotase activity 1 -1.12 1.14 1.63 1.21 1.33 1.0 1.05
6,7-dihydropteridine reductase activity 1 2.26 1.17 1.35 1.12 1.23 1.64 1.14
dihydrouracil dehydrogenase (NAD+) activity 1 -2.4 1.52 -1.09 1.53 -1.18 -2.54 -1.54
dimethylallyltranstransferase activity 2 2.38 1.13 2.21 -1.02 1.58 1.4 1.7
diphosphomevalonate decarboxylase activity 1 2.36 -1.19 -1.1 1.02 -1.17 1.09 1.24
diphthine synthase activity 1 1.75 1.22 1.1 1.3 1.08 -1.18 -1.03
dodecenoyl-CoA delta-isomerase activity 5 1.65 1.02 -1.16 1.25 1.08 1.17 -1.36
dopachrome isomerase activity 2 2.9 -1.22 -1.25 -1.08 -1.28 3.34 -1.14
dolichol kinase activity 1 -2.66 1.27 -1.76 1.39 1.67 -4.72 -1.84
dolichyl-phosphate-mannose-protein mannosyltransferase activity 2 1.57 1.01 1.07 -1.18 -1.11 1.61 1.23
dUTP diphosphatase activity 1 -1.36 -1.27 1.07 1.7 1.82 -3.47 -2.13
ecdysteroid UDP-glucosyltransferase activity 2 -2.06 1.41 -1.15 1.08 1.07 -2.31 -1.09
electron-transferring-flavoprotein dehydrogenase activity 1 2.09 1.59 -1.41 1.19 1.36 1.02 -1.19
endopeptidase activity 433 -1.75 -1.28 -1.35 -1.08 -1.23 -1.79 -1.45
aminopeptidase activity 36 -2.28 -1.12 -1.52 1.05 1.14 -1.43 -1.98
metalloexopeptidase activity 41 -2.37 -1.56 -1.46 1.02 -1.31 -2.4 -1.85
carboxypeptidase activity 35 -2.91 -1.85 -1.55 -1.01 -1.63 -3.14 -1.86
metallocarboxypeptidase activity 24 -4.15 -2.21 -1.86 -1.01 -1.57 -4.07 -2.61
serine-type carboxypeptidase activity 11 -1.26 -1.29 -1.05 -1.03 -1.8 -1.77 1.1
aspartic-type endopeptidase activity 19 -1.6 -1.03 1.15 -1.16 -1.46 -1.86 -1.32
calcium-dependent cysteine-type endopeptidase activity 4 2.12 1.16 1.44 1.14 1.21 1.24 1.16
lysosome 28 -2.58 -1.1 -2.35 1.15 -1.08 -2.06 -3.03
pyroglutamyl-peptidase activity 2 2.37 -1.16 1.04 -1.04 1.14 1.57 1.04
ubiquitin thiolesterase activity 27 1.19 1.22 1.57 1.17 1.42 1.39 1.24
metallopeptidase activity 153 -1.78 -1.24 -1.3 1.02 -1.0 -1.44 -1.51
peptidyl-dipeptidase activity 6 -1.43 -1.17 -1.51 -1.07 1.03 1.0 -1.19
vacuole 54 -2.1 -1.04 -1.32 -1.01 -1.13 -1.28 -1.9
serine-type peptidase activity 288 -2.24 -1.4 -1.61 -1.12 -1.45 -2.28 -1.59
tripeptidyl-peptidase activity 2 -2.48 1.24 -1.3 1.26 1.28 -1.53 -1.15
peptidase activity 576 -1.77 -1.28 -1.36 -1.05 -1.15 -1.74 -1.45
epoxide hydrolase activity 3 -2.11 1.3 -1.14 -1.06 -1.44 -4.35 1.38
ethanolamine kinase activity 2 1.11 1.13 1.36 1.19 1.43 2.57 1.13
ethanolamine-phosphate cytidylyltransferase activity 1 1.81 -1.85 1.07 -1.42 1.03 1.7 2.82
ethanolaminephosphotransferase activity 1 -1.35 1.28 1.66 1.08 1.2 1.32 1.18
farnesyltranstransferase activity 2 1.07 1.18 1.54 1.21 1.32 1.31 -1.04
fatty acid synthase activity 8 1.58 -1.38 -1.32 -1.5 -1.29 1.18 1.72
[acyl-carrier-protein] S-acetyltransferase activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
[acyl-carrier-protein] S-malonyltransferase activity 3 2.14 -1.05 -1.1 -1.07 1.17 1.47 1.42
3-oxoacyl-[acyl-carrier-protein] synthase activity 3 2.25 -1.02 -1.08 -1.11 1.15 1.9 1.44
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
oleoyl-[acyl-carrier-protein] hydrolase activity 2 3.49 -1.07 -1.08 -1.15 1.4 1.97 2.1
fatty-acyl-CoA synthase activity 1 2.47 -1.2 -1.84 1.79 2.31 -2.71 -1.43
ferroxidase activity 3 -1.88 -2.6 -2.43 -2.04 1.07 -1.41 2.03
iron ion transmembrane transporter activity 7 1.31 -1.87 -2.05 -1.74 -1.19 1.52 1.79
ferredoxin-NADP+ reductase activity 1 -1.19 1.24 1.2 1.43 1.53 -1.12 -1.13
tetrahydrofolylpolyglutamate synthase activity 2 -1.63 1.22 -1.26 1.27 -1.21 -1.7 -1.32
S-(hydroxymethyl)glutathione dehydrogenase activity 1 1.29 1.1 1.03 1.22 1.29 1.66 -1.14
formate-tetrahydrofolate ligase activity 1 -2.72 1.36 -1.4 1.55 -1.7 -1.17 -2.58
fructose-2,6-bisphosphate 2-phosphatase activity 1 1.09 -1.34 2.59 -1.04 1.14 3.38 -1.06
fructose-bisphosphate aldolase activity 1 1.83 1.08 -1.27 -1.04 1.23 2.05 1.42
fumarylacetoacetase activity 1 2.81 -1.06 -1.21 -1.09 1.58 2.01 -1.24
geranyltranstransferase activity 2 2.38 1.13 2.21 -1.02 1.58 1.4 1.7
glucosamine-6-phosphate deaminase activity 1 -1.22 1.14 1.64 1.24 2.02 -2.96 -2.72
glucosamine 6-phosphate N-acetyltransferase activity 1 1.02 1.09 -1.02 1.16 1.08 -1.06 2.5
glucose dehydrogenase activity 4 2.07 -1.33 -1.32 -1.38 -1.39 2.15 -1.49
glucose-6-phosphate dehydrogenase activity 2 1.97 -1.14 -2.0 -1.18 -1.53 1.18 1.65
glucose-6-phosphate isomerase activity 1 4.0 1.26 -2.38 -1.3 -1.5 3.87 2.36
glucosylceramidase activity 3 -3.7 -1.06 -2.39 1.57 -1.6 -3.65 -2.05
glutamate 5-kinase activity 1 -29.94 1.93 -2.31 -1.05 -1.13 -7.63 1.24
glutamate-5-semialdehyde dehydrogenase activity 1 -29.94 1.93 -2.31 -1.05 -1.13 -7.63 1.24
glutamate dehydrogenase (NAD+) activity 1 -1.32 -1.9 1.3 -2.14 3.35 4.87 -4.48
glutamate dehydrogenase [NAD(P)+] activity 2 -1.13 -1.34 1.15 -1.41 1.89 2.28 -2.14
glutamate synthase (NADPH) activity 1 2.14 1.19 1.24 1.03 -1.73 3.68 2.51
glutamate-ammonia ligase activity 2 1.91 -1.99 2.01 -1.44 1.52 -1.73 -1.25
glutamate-cysteine ligase activity 2 -1.84 1.49 -1.21 1.04 -1.06 1.03 1.54
glutamine-fructose-6-phosphate transaminase (isomerizing) activity 2 -1.0 -1.44 1.48 -1.44 1.38 1.11 2.78
glutaryl-CoA dehydrogenase activity 1 -1.51 -1.6 -1.42 1.8 -1.74 2.0 -2.55
glutathione-disulfide reductase activity 1 -1.86 1.42 -1.95 1.12 1.15 -1.81 1.13
glutathione synthase activity 1 -4.56 1.3 -1.17 1.44 -1.72 -2.63 -1.17
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity 3 1.41 -1.11 -1.14 -1.08 -1.06 1.76 1.01
glycerol-3-phosphate O-acyltransferase activity 2 3.16 -1.05 -1.54 1.04 2.3 -1.34 1.05
glycerol-3-phosphate dehydrogenase [NAD+] activity 2 1.2 1.12 -1.49 1.16 1.79 -1.21 -1.08
glycine hydroxymethyltransferase activity 1 4.17 -1.15 1.23 1.12 1.08 1.16 -1.19
glycogen (starch) synthase activity 1 3.34 -1.14 1.48 -1.05 1.39 2.94 1.3
glycine decarboxylation via glycine cleavage system 1 1.73 -1.01 1.7 -1.04 1.38 3.31 -1.03
glycine dehydrogenase (decarboxylating) activity 1 -1.37 -1.08 -1.16 -1.21 -1.14 1.68 -1.06
glycolipid mannosyltransferase activity 1 -1.85 1.22 -1.04 1.31 1.1 -2.17 1.06
glycylpeptide N-tetradecanoyltransferase activity 1 -1.49 1.29 1.71 1.24 1.7 1.05 1.0
guanosine-diphosphatase activity 1 -1.51 1.28 -1.3 1.09 -1.1 -3.57 1.37
guanylate kinase activity 5 3.22 1.04 1.21 -1.15 1.05 2.62 1.29
heme oxygenase (decyclizing) activity 1 2.0 1.05 2.09 1.06 1.46 2.34 1.12
heparan sulfate 2-O-sulfotransferase activity 2 2.25 1.13 1.26 1.01 1.22 1.54 1.62
hexokinase activity 4 -1.31 1.0 -1.96 1.11 1.37 1.21 -1.77
holocytochrome-c synthase activity 1 1.66 1.03 1.71 1.06 1.0 2.28 -1.41
hyalurononglucosaminidase activity 1 1.16 1.5 1.47 1.26 1.67 1.16 1.31
hydroxyacylglutathione hydrolase activity 1 -2.43 1.25 -1.81 1.44 1.13 -2.07 -1.36
hydroxymethylglutaryl-CoA lyase activity 1 -1.23 1.82 1.48 1.33 1.52 1.63 1.08
hydroxymethylglutaryl-CoA synthase activity 1 1.84 -1.29 1.3 -1.14 1.76 1.59 1.19
iduronate-2-sulfatase activity 1 1.62 1.05 1.28 1.01 1.11 1.28 1.12
phosphatidylinositol phosphate kinase activity 6 -1.3 1.22 1.48 1.12 1.58 1.08 1.01
phosphatidylinositol kinase activity 5 -1.09 1.17 1.62 1.11 1.75 1.32 1.12
phosphatidylinositol bisphosphate kinase activity 3 -1.46 1.15 1.53 1.18 1.77 -1.09 -1.14
1-phosphatidylinositol 4-kinase activity 2 1.44 1.21 1.76 1.02 1.71 2.28 1.63
phosphatidylinositol phospholipase C activity 2 2.58 1.12 1.89 -1.08 1.02 1.84 1.76
phosphatidylinositol trisphosphate phosphatase activity 1 2.96 1.13 1.75 -1.2 1.98 1.94 1.75
inositol phosphate phosphatase activity 13 1.85 -1.04 -1.08 -1.1 1.15 1.89 1.3
phosphatidylinositol-3-phosphatase activity 1 -1.51 1.05 1.08 1.24 -1.11 -1.13 -1.35
inositol-1,4-bisphosphate 1-phosphatase activity 1 3.45 -1.15 1.32 1.0 -1.07 1.6 -1.16
inositol trisphosphate phosphatase activity 6 1.66 1.07 1.37 -1.03 1.33 2.5 1.26
inositol-polyphosphate 5-phosphatase activity 3 1.23 1.22 1.55 1.08 1.34 1.47 1.38
isocitrate dehydrogenase activity 7 1.09 1.14 1.28 -1.23 1.01 1.93 1.09
isocitrate dehydrogenase (NAD+) activity 6 1.03 1.08 1.46 -1.19 1.02 2.18 1.06
isocitrate dehydrogenase (NADP+) activity 1 1.5 1.55 -1.65 -1.56 -1.01 -1.09 1.26
isopentenyl-diphosphate delta-isomerase activity 1 3.32 -1.02 1.27 1.26 1.27 1.92 1.53
lactate dehydrogenase activity 2 1.05 1.2 1.7 -1.34 -1.08 -2.44 1.33
L-lactate dehydrogenase activity 2 1.05 1.2 1.7 -1.34 -1.08 -2.44 1.33
lactoylglutathione lyase activity 1 -1.59 1.09 -1.01 1.22 -1.05 -1.39 -1.43
leukotriene-A4 hydrolase activity 1 -1.74 1.11 -2.01 1.51 1.27 -1.87 -1.55
lipoprotein lipase activity 5 -2.69 -1.1 -1.42 1.06 1.23 -1.76 -1.32
long-chain fatty acid-CoA ligase activity 7 1.81 -1.3 -1.35 1.09 1.2 -1.91 -1.26
malic enzyme activity 4 -1.07 1.26 1.14 -1.52 -1.06 1.05 1.65
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity 4 -1.07 1.26 1.14 -1.52 -1.06 1.05 1.65
mannose-1-phosphate guanylyltransferase activity 2 -2.09 1.14 1.2 1.25 1.24 -1.89 1.17
mannose-6-phosphate isomerase activity 2 3.41 1.03 1.33 -1.05 -1.02 3.9 1.9
methenyltetrahydrofolate cyclohydrolase activity 2 1.63 -1.3 -1.28 -1.04 -1.47 2.82 -1.53
methionine adenosyltransferase activity 1 1.6 1.05 1.23 -1.23 1.41 1.78 1.98
methionyl-tRNA formyltransferase activity 1 1.38 1.09 1.78 1.2 1.53 2.7 -1.25
mRNA guanylyltransferase activity 1 1.69 1.28 1.3 1.3 1.17 1.5 1.34
methylcrotonoyl-CoA carboxylase activity 2 1.38 1.49 1.32 1.28 1.37 1.61 1.17
methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity 1 2.55 -3.49 -3.06 -4.0 -1.9 6.63 -1.86
methylenetetrahydrofolate dehydrogenase (NAD+) activity 1 7.21 -2.31 -1.17 -1.68 -1.27 9.3 1.1
methylenetetrahydrofolate dehydrogenase (NADP+) activity 2 1.63 -1.3 -1.28 -1.04 -1.47 2.82 -1.53
methylenetetrahydrofolate reductase (NADPH) activity 1 1.73 -1.17 -1.14 -1.13 -1.11 2.12 -1.29
methylmalonate-semialdehyde dehydrogenase (acylating) activity 1 -1.74 1.44 -1.08 -1.1 -1.07 1.5 1.28
monooxygenase activity 35 1.52 -1.2 -1.23 -1.13 -1.16 -1.04 1.06
N,N-dimethylaniline monooxygenase activity 2 1.33 1.51 -1.79 -1.37 -1.35 1.43 1.59
peptidylglycine monooxygenase activity 1 2.74 1.3 1.75 1.08 1.98 1.97 2.28
phenylalanine 4-monooxygenase activity 2 1.24 -1.3 -1.46 -1.42 -1.18 2.11 -1.36
tryptophan 5-monooxygenase activity 2 1.24 -1.3 -1.46 -1.42 -1.18 2.11 -1.36
tyrosine 3-monooxygenase activity 1 -1.05 -1.1 1.05 1.12 -1.1 -1.1 1.78
inositol-3-phosphate synthase activity 1 1.86 -1.46 -1.12 -1.51 1.13 1.83 1.71
nicotinate-nucleotide diphosphorylase (carboxylating) activity 1 8.31 1.05 -1.79 -1.54 -1.19 1.17 2.54
nicotinate phosphoribosyltransferase activity 1 8.31 1.05 -1.79 -1.54 -1.19 1.17 2.54
ribonuclease III activity 4 1.01 1.12 1.7 -1.0 1.33 1.5 1.2
deoxyribonuclease II activity 1 3.57 -3.74 -3.12 -4.14 -2.27 -1.33 4.32
5'-3' exoribonuclease activity 2 -1.11 1.53 1.16 1.33 1.34 -1.11 1.19
poly(A)-specific ribonuclease activity 2 1.33 1.15 1.69 1.2 1.62 2.01 1.48
octanol dehydrogenase activity 1 1.29 1.1 1.03 1.22 1.29 1.66 -1.14
hydrolase activity, hydrolyzing O-glycosyl compounds 93 -1.83 -1.29 -2.4 -1.22 -1.47 -1.78 -1.26
alpha,alpha-trehalase activity 3 -2.73 1.23 -2.68 1.17 -1.22 -2.41 1.01
alpha-amylase activity 2 -34.84 -2.22 -3.89 2.13 -10.58 -52.06 -2.46
alpha-galactosidase activity 1 -4.17 1.11 -1.19 -1.11 -1.3 -2.49 3.87
alpha-glucosidase activity 13 -7.82 -1.11 -3.92 1.01 -2.19 -4.92 -2.34
alpha-mannosidase activity 9 -14.64 -1.14 -7.39 1.54 -1.15 -14.33 -25.61
alpha-L-fucosidase activity 1 -1.1 -1.19 -1.53 -1.9 -1.86 -1.28 7.99
alpha-N-acetylglucosaminidase activity 1 -1.03 -1.29 -2.28 -2.21 -1.93 20.24 3.19
beta-N-acetylhexosaminidase activity 4 2.6 -1.04 -1.38 1.02 1.14 -1.03 1.23
beta-galactosidase activity 2 -4.22 1.94 -2.65 -1.31 -2.65 -1.75 -2.68
beta-glucuronidase activity 2 -2.98 1.22 1.8 1.28 1.95 -1.65 1.15
beta-mannosidase activity 1 -5.95 1.18 1.25 1.37 1.4 -3.3 -1.02
chitinase activity 17 -1.5 -2.2 -3.34 -2.35 -1.62 1.11 2.06
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 5 1.56 1.24 -1.27 -1.11 -1.07 2.0 1.29
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity 2 2.21 -1.18 -1.12 1.09 -1.0 4.22 1.53
mannosyl-oligosaccharide glucosidase activity 1 1.11 1.54 -1.06 1.25 1.09 -1.47 1.06
oligo-1,6-glucosidase activity 1 -7.77 -4.97 -3.61 4.46 -5.62 -8.7 -6.61
dolichyl-diphosphooligosaccharide-protein glycotransferase activity 2 -2.3 1.16 -1.02 1.14 1.1 -1.42 1.33
dolichyl-phosphate beta-glucosyltransferase activity 1 -1.18 1.16 1.9 1.06 1.5 -1.14 1.68
dolichyl-phosphate beta-D-mannosyltransferase activity 1 1.01 1.25 1.35 1.09 1.77 -1.32 1.33
ornithine decarboxylase activity 2 -1.3 -1.56 -1.58 -1.19 -1.51 1.68 -1.8
ornithine-oxo-acid transaminase activity 2 -3.39 1.33 -4.62 1.16 1.17 -3.49 1.2
orotate phosphoribosyltransferase activity 1 1.61 1.06 1.09 1.15 1.38 -1.09 1.01
orotidine-5'-phosphate decarboxylase activity 1 1.61 1.06 1.09 1.15 1.38 -1.09 1.01
oxoglutarate dehydrogenase (succinyl-transferring) activity 2 -2.58 1.25 1.08 -1.04 1.34 -1.08 -1.45
pantothenate kinase activity 1 2.17 1.37 -1.41 1.23 1.4 -1.72 1.12
pantetheine-phosphate adenylyltransferase activity 1 -1.07 1.17 -1.47 1.46 1.3 -2.5 -1.32
peptide alpha-N-acetyltransferase activity 2 -1.32 1.41 1.74 1.19 1.16 -1.05 -1.05
cyclosporin A binding 1 -1.56 1.12 -1.6 -1.09 -1.49 -1.56 -1.26
glutathione peroxidase activity 8 -1.36 1.09 -1.0 -1.35 -1.25 -2.14 1.1
phosphatidate cytidylyltransferase activity 1 3.07 1.1 2.07 -1.42 3.13 -1.11 1.4
phosphatidylserine decarboxylase activity 1 2.68 -1.15 1.36 1.05 1.26 2.6 1.26
phosphoacetylglucosamine mutase activity 1 -2.86 1.51 1.12 1.09 1.09 -5.18 1.1
phosphoenolpyruvate carboxykinase activity 2 -2.6 -1.77 1.37 -1.78 2.07 1.05 -1.67
phosphoenolpyruvate carboxykinase (GTP) activity 2 -2.6 -1.77 1.37 -1.78 2.07 1.05 -1.67
phosphoglucomutase activity 1 3.54 -1.2 -2.31 -1.28 -1.28 4.52 1.34
phosphogluconate dehydrogenase (decarboxylating) activity 4 1.7 1.24 -1.62 -1.03 -1.05 1.36 1.59
phosphoglycerate dehydrogenase activity 2 2.82 -1.08 -1.11 1.42 -1.05 1.77 -1.02
phosphoglycerate kinase activity 2 1.52 -1.04 -1.22 1.01 -1.05 1.8 -1.0
phosphoglycerate mutase activity 4 1.53 -1.02 -1.23 -1.07 -1.15 1.51 1.11
phospholipase activity 42 -2.02 -1.32 -1.4 -1.24 -1.44 -1.94 -1.19
lysophospholipase activity 5 -1.5 -1.08 -1.31 -1.5 -1.48 1.02 1.77
phospholipase A2 activity 10 1.72 -1.05 -1.16 -1.1 -1.05 -1.02 1.07
calcium-independent phospholipase A2 activity 2 1.71 1.33 1.36 1.12 1.41 1.4 1.33
phosphomevalonate kinase activity 1 2.16 -1.1 1.03 -1.13 1.06 2.2 1.18
phosphopantothenate--cysteine ligase activity 1 -1.95 1.39 1.68 1.01 1.49 -1.24 1.08
phosphopantothenoylcysteine decarboxylase activity 1 3.72 -1.03 1.39 1.15 1.52 2.47 1.16
phosphopyruvate hydratase activity 1 1.97 1.06 -1.39 -1.17 -1.32 2.59 1.17
phosphoribosylaminoimidazole carboxylase activity 2 -1.17 -1.46 -1.46 -1.15 -1.17 1.65 -1.07
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity 2 -1.17 -1.46 -1.46 -1.15 -1.17 1.65 -1.07
phosphoribosylformylglycinamidine synthase activity 1 -1.91 1.54 -1.81 1.0 -1.5 -1.22 1.08
phosphoribosylaminoimidazolecarboxamide formyltransferase activity 1 -1.39 1.0 -1.49 -1.01 -1.06 1.63 -1.09
phosphorylase activity 1 2.98 -1.08 1.5 -1.31 1.12 4.86 1.33
phosphoserine phosphatase activity 1 2.48 1.99 -2.53 -1.16 1.91 2.86 1.87
O-phospho-L-serine:2-oxoglutarate aminotransferase activity 1 2.63 -1.02 -1.9 1.11 -1.04 2.51 1.93
poly(ADP-ribose) glycohydrolase activity 1 1.16 1.03 1.19 1.34 1.67 -1.1 1.01
polynucleotide 5'-phosphatase activity 1 1.69 1.28 1.3 1.3 1.17 1.5 1.34
polypeptide N-acetylgalactosaminyltransferase activity 14 -1.29 -1.23 -1.25 -1.28 -1.26 -1.61 1.75
porphobilinogen synthase activity 1 -2.33 1.65 -1.72 1.07 -2.09 -1.28 -1.14
iron ion transport 7 1.59 -1.3 -1.22 -1.23 -1.14 1.5 1.12
proline dehydrogenase activity 1 2.07 -7.1 -4.47 -7.74 -3.15 31.25 -1.33
protein farnesyltransferase activity 1 -1.83 -1.28 -1.22 1.05 -1.01 -1.04 2.75
protein geranylgeranyltransferase activity 6 -1.57 1.19 1.22 1.14 1.21 -1.62 1.21
CAAX-protein geranylgeranyltransferase activity 2 -2.28 1.15 1.11 1.06 1.05 -2.22 1.78
protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity 1 -2.13 1.18 1.09 1.41 1.8 -1.71 -1.76
protein histidine kinase activity 3 1.12 -1.13 1.03 -1.08 1.69 1.52 -1.14
transmembrane receptor protein serine/threonine kinase activity 5 -1.03 1.52 1.48 1.18 1.61 1.07 1.49
DNA-dependent protein kinase activity 1 1.33 1.54 1.93 1.1 1.72 1.13 1.74
calmodulin-dependent protein kinase activity 8 2.03 1.07 1.21 1.02 1.3 2.02 1.5
elongation factor-2 kinase activity 2 1.62 1.17 1.62 -1.04 1.48 1.47 1.77
myosin light chain kinase activity 4 1.66 -1.14 1.36 -1.04 1.61 1.38 1.02
phosphorylase kinase activity 1 1.92 1.23 1.07 1.1 1.35 3.19 1.58
cyclic nucleotide-dependent protein kinase activity 6 -1.04 -1.05 1.23 -1.15 1.2 2.46 1.34
cAMP-dependent protein kinase activity 3 1.72 -1.04 1.4 -1.32 1.33 4.14 1.26
cGMP-dependent protein kinase activity 3 -1.85 -1.05 1.07 1.01 1.09 1.46 1.42
protein kinase C activity 7 1.66 -1.04 1.77 -1.14 1.06 2.51 1.12
calcium-dependent protein kinase C activity 3 1.12 1.04 2.13 -1.07 1.01 3.21 -1.04
G-protein coupled receptor kinase activity 3 1.16 1.4 1.53 1.09 1.29 1.52 1.29
JUN kinase activity 2 -1.09 1.03 1.52 1.15 1.41 -1.08 1.01
JUN kinase kinase kinase activity 2 1.23 1.27 1.56 1.2 1.54 1.23 1.3
MAP kinase kinase kinase activity 5 -1.39 1.21 1.48 1.15 1.82 1.09 1.04
MAPK/ERK kinase kinase activity 1 1.83 1.46 1.17 -1.02 1.24 1.79 1.33
ribosomal protein S6 kinase activity 1 -2.62 1.78 1.7 1.33 1.66 1.52 1.3
transmembrane receptor protein tyrosine kinase activity 21 1.55 -1.07 1.14 -1.01 1.13 1.58 1.42
non-membrane spanning protein tyrosine kinase activity 7 1.37 1.16 1.77 1.12 1.46 1.64 1.42
protein-L-isoaspartate (D-aspartate) O-methyltransferase activity 1 2.93 1.03 1.2 1.19 1.05 1.97 1.02
calcium-dependent protein serine/threonine phosphatase activity 6 1.52 -1.02 1.2 1.05 1.13 1.24 1.06
prenylated protein tyrosine phosphatase activity 1 1.54 1.27 2.19 -1.23 1.74 3.0 1.51
receptor signaling protein tyrosine phosphatase activity 3 2.8 -1.06 1.33 -1.06 1.35 3.49 1.47
pseudouridylate synthase activity 3 1.57 1.31 1.17 1.55 1.45 1.03 1.08
pyridoxamine-phosphate oxidase activity 3 1.93 1.06 -1.17 1.32 1.07 1.07 -1.07
pyrroline-5-carboxylate reductase activity 2 -1.77 1.27 -1.94 1.07 -1.03 -1.14 -1.01
pyruvate carboxylase activity 1 2.41 -1.07 -1.67 1.11 -2.11 1.65 1.08
pyruvate dehydrogenase activity 3 -1.02 1.01 1.31 1.1 -1.0 1.57 -1.25
pyruvate dehydrogenase (acetyl-transferring) activity 3 -1.02 1.01 1.31 1.1 -1.0 1.57 -1.25
pyruvate dehydrogenase (acetyl-transferring) kinase activity 1 1.67 -1.54 1.2 -1.13 7.02 3.44 1.09
[pyruvate dehydrogenase (lipoamide)] phosphatase activity 1 1.78 1.13 1.46 1.23 1.08 1.92 1.02
dihydrolipoyllysine-residue acetyltransferase activity 1 1.23 1.19 1.96 -1.07 1.35 3.33 1.11
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor 2 -2.27 -1.06 1.44 1.36 1.87 -1.61 -1.54
ribose phosphate diphosphokinase activity 2 2.41 1.04 1.7 -1.06 1.1 2.9 1.34
ribulose-phosphate 3-epimerase activity 1 3.69 1.12 -1.44 1.15 1.15 1.38 1.6
ribose-5-phosphate isomerase activity 1 2.8 1.42 -1.73 1.16 1.1 1.26 1.25
saccharopine dehydrogenase activity 1 1.21 1.36 -1.07 1.24 -1.06 1.55 1.4
saccharopine dehydrogenase (NAD+, L-lysine-forming) activity 1 1.21 1.36 -1.07 1.24 -1.06 1.55 1.4
selenide, water dikinase activity 2 1.76 1.25 1.23 1.04 1.04 1.62 -1.07
sepiapterin reductase activity 3 2.14 -1.76 -1.79 -1.65 -1.36 2.93 -1.29
serine C-palmitoyltransferase activity 2 -2.24 1.07 2.48 1.17 1.31 -1.71 -1.18
serine-pyruvate transaminase activity 1 1.1 -1.81 -2.08 -1.81 -1.6 3.21 -1.83
sphingomyelin phosphodiesterase activity 5 -5.07 -3.51 -4.56 1.49 -1.12 -3.62 -4.08
stearoyl-CoA 9-desaturase activity 7 -1.4 1.15 -1.2 1.26 1.01 -1.67 -1.18
sterol esterase activity 1 -139.1 -18.6 -1.99 2.08 -24.32 -152.96 -197.4
sterol O-acyltransferase activity 3 -2.3 -1.64 -1.24 1.46 1.26 -1.59 -2.16
succinate-semialdehyde dehydrogenase activity 1 -2.19 1.37 2.06 1.34 1.0 1.58 -1.11
sulfate adenylyltransferase activity 1 -2.63 1.06 1.41 1.07 1.11 -1.64 -1.02
sulfate adenylyltransferase (ATP) activity 1 -2.63 1.06 1.41 1.07 1.11 -1.64 -1.02
sulfinoalanine decarboxylase activity 1 -1.56 1.66 -7.28 1.14 -1.03 -3.47 1.18
thiosulfate sulfurtransferase activity 1 1.15 -1.38 2.62 1.38 1.04 -1.42 -1.83
threonine aldolase activity 1 1.44 -1.1 -1.93 1.6 -1.06 1.8 -2.26
L-threonine ammonia-lyase activity 1 -3.81 -2.74 -2.14 -1.15 11.07 -1.69 -3.46
thymidylate kinase activity 1 1.27 1.13 1.91 1.21 1.41 -1.17 -1.08
thymidylate synthase activity 1 -1.63 -1.08 1.19 1.46 1.72 -2.2 -2.17
sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity 1 3.18 1.11 -3.27 1.02 -1.44 -1.1 1.46
transketolase activity 2 2.03 1.17 -1.56 1.02 1.12 1.44 1.62
trehalose-phosphatase activity 2 5.88 -2.14 -1.49 -1.62 1.02 4.6 1.12
triglyceride lipase activity 38 -3.83 -1.33 -1.88 -1.09 -1.77 -4.41 -2.22
aspartate-tRNA ligase activity 1 -1.97 1.61 1.28 -1.18 1.45 -1.88 1.38
cysteine-tRNA ligase activity 2 -1.01 1.37 1.43 1.08 1.22 1.24 1.76
histidine-tRNA ligase activity 1 -1.32 1.37 -1.07 1.31 -1.14 -1.74 -1.19
isoleucine-tRNA ligase activity 2 1.35 1.22 1.54 1.02 1.38 1.61 1.38
methionine-tRNA ligase activity 2 -1.59 1.18 1.28 1.38 1.17 -1.27 -1.03
threonine-tRNA ligase activity 2 -1.65 1.24 1.06 1.13 -1.08 -1.17 1.02
valine-tRNA ligase activity 2 -1.62 1.31 1.29 1.15 1.04 -1.25 1.17
tryptophan 2,3-dioxygenase activity 1 1.33 -1.46 -1.36 -1.56 -1.39 2.84 -1.33
tyrosine decarboxylase activity 2 2.12 -1.17 -1.18 -1.17 1.11 1.9 -1.07
ubiquitin activating enzyme activity 3 1.07 1.19 1.42 1.25 1.55 1.31 1.05
ubiquitin-specific protease activity 8 1.17 1.21 1.8 1.18 1.58 1.96 1.41
uracil DNA N-glycosylase activity 2 2.91 -1.23 -1.13 -1.34 1.04 2.88 1.17
uracil phosphoribosyltransferase activity 1 1.85 1.12 1.41 1.03 1.01 1.67 1.33
urate oxidase activity 1 3.87 -2.08 -2.11 -2.0 -1.26 -1.05 -1.64
uridine kinase activity 2 4.18 -1.72 1.72 -1.65 -1.27 3.76 1.43
uridine phosphorylase activity 3 -2.2 -1.73 1.35 -1.47 -1.37 -2.19 1.39
uroporphyrinogen decarboxylase activity 1 2.27 -1.08 -1.25 1.43 1.04 1.18 1.26
xanthine dehydrogenase activity 2 1.25 1.78 -1.17 -1.32 -1.19 -1.3 1.66
xanthine oxidase activity 1 1.38 1.39 -1.09 1.59 1.39 -1.89 1.34
cyclin-dependent protein kinase inhibitor activity 2 1.97 -1.0 1.05 1.02 1.15 1.58 1.04
protein phosphatase inhibitor activity 7 1.59 -1.08 -1.01 -1.03 1.27 1.27 -1.01
protein serine/threonine phosphatase inhibitor activity 1 1.57 1.1 -1.11 1.22 1.13 -1.01 -1.25
endopeptidase inhibitor activity 73 1.41 -1.48 -1.45 -1.49 -1.3 1.51 1.04
serine-type endopeptidase inhibitor activity 58 1.2 -1.48 -1.57 -1.54 -1.37 1.38 -1.05
cysteine-type endopeptidase inhibitor activity 6 3.11 -1.78 -1.05 -1.54 -1.18 1.44 1.41
carbohydrate binding 166 -1.92 -1.36 -1.53 -1.23 -1.33 -1.85 -1.01
boss receptor activity 1 2.09 -1.24 -1.34 -1.08 -1.33 -1.62 1.07
Wnt-activated receptor activity 5 1.17 1.03 1.52 -1.14 1.66 -1.04 1.31
Wnt receptor signaling pathway, calcium modulating pathway 2 1.15 1.15 1.16 1.02 1.3 1.14 2.54
calcitonin receptor activity 5 1.36 -1.25 1.11 -1.21 1.02 -1.07 1.56
N-methyl-D-aspartate selective glutamate receptor activity 5 -2.2 1.03 -1.01 -1.04 -1.02 -1.52 1.05
neuropeptide Y receptor activity 6 -1.12 -1.28 1.15 -1.08 1.23 2.07 -1.01
tachykinin receptor activity 6 -1.02 -1.12 1.07 -1.2 -1.05 1.79 1.44
transmembrane receptor protein tyrosine phosphatase activity 6 1.57 1.05 1.23 1.03 1.35 2.22 1.25
ephrin receptor activity 1 2.31 1.1 1.68 1.08 2.32 2.06 2.34
epidermal growth factor-activated receptor activity 1 2.54 -1.11 -1.09 1.14 1.59 3.23 1.89
fibroblast growth factor-activated receptor activity 3 1.8 -1.38 2.01 1.04 -1.27 -1.03 -1.21
insulin-activated receptor activity 1 1.01 1.43 1.57 1.5 2.27 1.72 1.64
insulin-like growth factor-activated receptor activity 2 -1.08 -1.38 -1.23 -1.3 -1.24 5.4 3.24
growth factor binding 5 -1.0 1.2 1.22 1.22 1.63 1.18 1.29
transforming growth factor beta-activated receptor activity 5 -1.03 1.52 1.48 1.18 1.61 1.07 1.49
transforming growth factor beta receptor activity, type I 3 -1.44 1.44 1.63 1.24 1.98 1.37 1.58
transforming growth factor beta receptor activity, type II 2 1.6 1.65 1.28 1.09 1.17 -1.35 1.36
tumor necrosis factor-activated receptor activity 1 10.08 -2.23 1.27 -2.86 -1.97 3.13 1.07
osmosensor activity 1 -6.38 -3.77 -11.1 -5.2 -1.19 28.07 -1.66
death receptor activity 1 10.08 -2.23 1.27 -2.86 -1.97 3.13 1.07
death receptor binding 1 1.78 1.11 1.56 1.24 1.76 -1.03 1.11
netrin receptor activity 2 -1.2 1.24 1.26 1.34 2.11 -1.46 1.04
KDEL sequence binding 1 -1.48 1.27 1.01 1.14 -1.01 -1.37 1.53
nuclear export signal receptor activity 3 1.18 1.05 2.95 1.07 1.92 2.19 1.34
peroxisome 39 1.3 -1.06 -1.53 1.05 1.16 -1.5 -1.16
peroxisomal membrane 14 1.87 1.14 -1.32 1.28 1.36 -1.33 -1.09
laminin receptor activity 1 -9.63 1.35 1.66 1.05 1.52 -7.44 1.13
transforming growth factor beta receptor, cytoplasmic mediator activity 4 1.26 1.21 1.59 1.07 1.32 1.36 1.28
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity 1 2.8 1.17 2.77 -1.14 1.51 2.43 1.42
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity 1 -2.15 1.12 -1.08 1.29 -1.07 -2.29 1.33
protein kinase A binding 3 -1.23 1.19 1.19 1.03 1.27 1.0 1.5
protein kinase C binding 5 1.76 1.33 1.56 1.07 1.48 1.92 1.83
guanyl-nucleotide exchange factor activity 52 1.11 1.15 1.38 1.01 1.29 1.52 1.26
ARF guanyl-nucleotide exchange factor activity 6 -1.22 1.21 1.27 -1.01 1.25 1.49 1.58
GDP-dissociation inhibitor activity 2 -1.01 -1.04 1.34 1.09 1.21 -1.08 -1.54
Rho GDP-dissociation inhibitor activity 1 -1.46 -1.08 1.63 1.09 1.3 -1.27 -1.71
Ran GTPase activator activity 1 1.34 1.36 1.62 1.42 1.91 1.35 1.2
fibroblast growth factor receptor binding 3 1.57 1.01 2.07 -1.12 1.29 2.72 1.05
ephrin receptor binding 1 1.81 1.29 1.78 1.1 1.94 2.77 1.53
anchored to plasma membrane 3 3.1 -2.01 -3.22 -2.43 -1.37 2.44 1.37
frizzled binding 3 -1.65 -1.07 1.18 -1.29 1.31 1.28 1.51
frizzled-2 binding 2 -1.8 1.01 1.43 -1.3 -1.11 1.61 2.1
patched binding 2 -1.41 -1.16 1.11 1.42 1.34 -1.32 -2.31
sevenless binding 2 2.05 1.08 1.52 1.1 1.59 1.98 1.31
smoothened binding 1 1.33 1.48 1.27 1.38 1.17 1.23 1.56
Toll binding 6 2.0 -1.13 -1.18 -1.1 -1.05 3.64 1.27
torso binding 2 4.82 -2.22 -1.24 -1.06 1.12 2.59 1.13
cytokine activity 3 2.09 -1.14 -1.06 -1.07 1.06 1.89 1.58
epidermal growth factor receptor binding 8 2.02 -1.02 1.33 1.03 1.43 2.13 1.51
positive regulation of epidermal growth factor-activated receptor activity 1 -1.21 1.16 2.16 -1.11 1.4 1.68 1.37
insulin-like growth factor receptor binding 1 2.22 1.3 2.31 -1.1 1.87 2.8 1.91
transforming growth factor beta receptor binding 7 1.67 1.01 -1.0 -1.48 -1.16 1.33 1.27
tumor necrosis factor receptor binding 1 1.09 -1.11 -1.93 -1.35 4.12 -1.38 6.18
hormone activity 52 -1.48 -1.33 -1.19 -1.09 -1.16 -1.59 -1.16
neuropeptide hormone activity 35 -1.76 -1.5 -1.27 -1.18 -1.19 -1.89 -1.23
structural constituent of cell wall 2 4.29 -1.81 -1.38 -1.64 -1.67 1.06 1.01
collagen 3 1.14 -1.43 1.08 -1.25 -1.21 1.82 -1.14
structural constituent of eye lens 1 -23.09 -8.59 -4.86 2.62 -1.02 -36.83 -31.54
intracellular ligand-gated ion channel activity 7 1.42 1.03 1.28 1.0 1.1 1.59 1.16
intracellular ligand-gated calcium channel activity 3 1.97 -1.03 1.18 1.08 1.09 1.76 1.17
ryanodine-sensitive calcium-release channel activity 1 3.82 -1.03 1.3 -1.12 1.16 2.73 1.18
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 1 2.52 1.29 3.07 -1.16 1.37 5.13 2.97
volume-sensitive anion channel activity 2 1.92 1.08 -1.06 -1.08 2.11 2.25 1.09
calcium activated cation channel activity 3 -1.25 -1.55 1.25 1.49 -1.39 -1.46 -1.49
inhibitory extracellular ligand-gated ion channel activity 4 -1.54 1.26 1.47 -1.43 -1.72 -1.63 -1.04
inward rectifier potassium channel activity 4 -1.18 -1.13 -1.58 -3.21 -3.46 1.87 -1.7
gap junction channel activity 6 -1.73 -1.09 -1.05 -1.09 -1.25 -1.21 1.35
voltage-gated chloride channel activity 3 -1.31 1.23 -1.16 1.19 1.05 1.88 1.52
A-type (transient outward) potassium channel activity 2 3.38 -1.08 1.04 -1.08 1.22 1.8 -1.38
open rectifier potassium channel activity 3 2.34 -1.1 -1.13 -1.16 1.03 1.04 -1.38
amine transmembrane transporter activity 58 -1.3 -1.08 -1.61 -1.23 -1.04 -1.08 -1.11
hydrogen:amino acid symporter activity 2 1.74 1.43 -1.72 -1.09 1.17 -1.0 1.38
amino acid transmembrane transporter activity 53 -1.39 -1.07 -1.67 -1.24 -1.03 -1.11 -1.1
L-tyrosine transmembrane transporter activity 2 3.0 -1.1 1.15 -1.28 -1.42 2.49 1.13
organic acid:sodium symporter activity 8 -1.17 1.19 -1.85 -1.42 -1.96 -1.64 1.15
L-glutamate transmembrane transporter activity 4 -2.07 1.33 -5.17 -2.48 -1.62 -1.72 -2.15
high-affinity glutamate transmembrane transporter activity 1 -51.3 1.56 -15.93 -1.24 2.78 -3.27 -134.18
inorganic phosphate transmembrane transporter activity 3 2.26 -1.45 1.37 -1.34 1.47 3.74 -1.03
high affinity inorganic phosphate:sodium symporter activity 18 -3.67 1.02 -3.81 -1.03 -1.98 -1.81 -2.84
neurotransmitter transporter activity 24 1.11 -1.3 -1.53 -1.28 1.11 1.77 1.29
neurotransmitter:sodium symporter activity 18 1.0 -1.4 -1.72 -1.34 1.19 1.93 1.23
sugar:hydrogen symporter activity 8 1.06 -1.15 -1.17 -1.12 -1.18 -1.05 1.82
glucose transmembrane transporter activity 15 -1.29 -1.15 -1.91 -1.13 -1.42 -1.88 1.23
tricarboxylate secondary active transmembrane transporter activity 3 -1.58 1.64 -1.92 -1.18 -1.42 1.07 1.16
water transmembrane transporter activity 7 -2.13 1.26 -1.34 -1.07 -2.07 -2.5 -1.23
secondary active transmembrane transporter activity 155 -1.44 -1.11 -1.62 -1.18 -1.13 1.21 -1.17
manganese ion transmembrane transporter activity 2 -1.53 1.28 -1.11 1.02 -1.23 -1.54 1.12
sodium:potassium-exchanging ATPase activity 8 1.13 -1.11 1.22 -1.35 -1.0 1.53 1.06
cation:sugar symporter activity 8 1.06 -1.15 -1.17 -1.12 -1.18 -1.05 1.82
nucleoside:sodium symporter activity 2 -7.59 1.47 -2.97 -1.0 -2.3 -5.85 -2.0
cation:amino acid symporter activity 13 1.13 -1.27 -2.32 -1.57 1.11 1.18 1.23
proton-dependent oligopeptide secondary active transmembrane transporter activity 3 1.69 -1.17 -1.51 -1.15 -1.07 1.17 1.2
synaptic vesicle amine transmembrane transporter activity 1 9.63 -2.21 -1.97 -1.79 -1.94 -1.46 -1.99
calcium:sodium antiporter activity 2 -1.37 1.7 1.3 -1.23 1.65 2.01 1.96
sodium:phosphate symporter activity 21 -3.19 1.03 -3.12 -1.03 -1.89 -1.53 -2.45
monovalent cation:hydrogen antiporter activity 4 -2.37 -1.01 -1.35 1.01 -1.74 3.33 -1.27
inorganic anion exchanger activity 2 -3.68 -3.74 3.73 -4.0 -1.27 -1.18 -1.53
CMP-N-acetylneuraminate transmembrane transporter activity 3 -1.73 1.25 -1.03 1.28 -1.06 -1.84 1.23
UDP-galactose transmembrane transporter activity 6 -1.21 1.24 1.0 1.15 1.18 -1.35 1.53
UDP-glucuronic acid transmembrane transporter activity 4 -1.46 1.25 1.0 1.26 1.04 -1.57 1.43
UDP-N-acetylgalactosamine transmembrane transporter activity 2 -2.31 1.25 -1.08 1.21 1.09 -2.5 1.48
UDP-xylose transmembrane transporter activity 3 -1.4 1.3 1.05 1.18 -1.06 -1.45 1.9
carnitine:acyl carnitine antiporter activity 2 1.34 1.32 -1.91 1.22 1.14 -1.7 -1.23
synaptic vesicle to endosome fusion 1 1.73 -1.06 2.32 1.09 1.39 3.26 1.36
synaptic vesicle targeting 9 1.07 1.25 1.5 1.16 1.39 1.39 1.23
soluble NSF attachment protein activity 6 1.55 1.06 1.18 1.07 1.23 1.28 1.16
steroid binding 19 -2.28 -1.49 -1.79 1.11 -1.16 -2.3 -2.31
retinoid binding 8 2.32 -6.6 -7.06 -2.49 -1.68 1.78 1.1
fatty acid binding 11 -1.61 -1.59 -2.07 -1.15 1.3 -1.68 -1.56
copper ion binding 20 -1.87 -1.23 -1.09 -1.21 -1.25 -1.59 1.03
detection of calcium ion 3 -1.58 -1.06 -1.06 1.03 1.08 -1.26 -1.33
cytoskeletal regulatory protein binding 1 -1.55 1.24 2.16 1.01 1.73 1.49 1.71
tropomyosin binding 3 5.21 -1.74 1.31 -1.52 1.36 3.43 -1.33
galactose binding 11 -1.6 -1.21 1.22 -1.04 -1.07 -1.49 -1.08
folic acid binding 4 -1.96 -1.02 -2.85 1.48 -1.35 -1.15 -2.07
phosphatidylinositol-4,5-bisphosphate binding 2 -1.07 1.2 1.71 1.09 1.37 1.09 1.1
protein tag 2 2.12 -1.08 -1.18 1.19 1.03 -1.14 1.1
collagen type IV 2 1.15 -1.7 -1.07 -1.48 -1.42 2.42 -1.33
basement membrane 10 1.55 -1.19 1.13 -1.32 1.1 2.13 1.42
basal lamina 3 2.42 -1.01 1.11 -1.14 1.47 4.1 1.43
laminin-1 complex 1 3.52 1.3 1.81 1.23 2.46 6.46 1.6
integrin complex 8 -1.75 1.03 1.23 -1.07 1.36 -1.33 1.18
interstitial matrix 1 -3.11 1.08 3.33 -1.03 2.28 -1.55 -1.14
nuclear inner membrane 7 1.5 -1.14 1.37 1.22 1.72 1.02 -1.06
integral to nuclear inner membrane 2 -1.02 -2.05 1.59 1.21 2.03 -1.95 -2.17
nuclear outer membrane 1 2.5 -1.28 -1.45 -1.24 1.61 3.68 4.91
nuclear envelope lumen 2 1.16 1.03 1.1 1.15 1.11 1.57 -1.14
Ran GTPase binding 7 -1.02 1.21 1.82 1.21 1.53 1.48 1.33
nucleolar ribonuclease P complex 1 1.84 1.03 1.1 1.42 1.17 1.05 -1.14
pre-replicative complex 9 -1.14 1.11 1.17 1.27 1.56 -1.1 -1.11
DNA replication factor C complex 5 1.37 1.06 1.26 1.45 1.6 1.11 -1.08
PCNA complex 2 -1.29 1.09 1.33 1.22 1.3 -1.6 -1.28
DNA replication factor A complex 3 1.13 1.13 1.31 1.42 1.65 1.03 -1.21
transcription factor TFIIE complex 2 1.86 1.06 1.16 1.23 1.25 1.2 1.16
chromatin assembly complex 8 1.08 -1.4 -1.04 -1.4 1.24 1.6 1.04
U12 snRNP 1 1.7 -1.05 -1.07 -1.09 -1.18 1.33 1.14
nuclear euchromatin 4 1.52 1.39 1.51 1.2 1.41 1.55 1.43
beta-heterochromatin 1 1.4 1.27 1.49 -1.01 1.2 1.7 1.58
nuclear telomeric heterochromatin 1 -1.17 1.26 1.25 1.08 2.11 -1.1 1.25
mitochondrial respiratory chain 68 1.11 1.0 1.19 1.01 1.07 1.57 -1.31
mitochondrial respiratory chain complex I 37 1.15 1.04 1.27 1.07 1.11 1.72 -1.29
mitochondrial proton-transporting ATP synthase complex 18 1.31 -1.01 1.22 -1.03 1.11 1.68 -1.22
proton-transporting ATP synthase complex, coupling factor F(o) 9 1.19 1.04 1.31 1.01 1.22 1.62 -1.14
mitochondrial proton-transporting ATP synthase, central stalk 1 1.03 1.03 1.17 1.01 1.11 1.58 -1.38
mitochondrial ribosome 72 1.04 1.07 1.23 1.29 1.25 1.45 -1.55
mitochondrial large ribosomal subunit 44 1.03 1.05 1.24 1.3 1.28 1.46 -1.6
lysosomal membrane 4 1.09 -1.11 -1.38 1.13 1.63 2.55 1.04
secondary lysosome 1 1.17 -2.03 2.67 -1.12 -2.24 1.02 -1.06
multivesicular body 6 -1.01 1.0 1.49 1.07 1.26 1.31 1.59
vacuolar membrane 30 -1.55 -1.0 1.28 -1.14 -1.08 1.41 -1.12
integral to peroxisomal membrane 5 1.37 1.29 -1.51 1.15 1.08 -1.33 -1.13
protein targeting to peroxisome 3 1.5 1.17 -1.6 1.44 1.46 -2.19 -1.64
peroxisomal part 14 1.87 1.14 -1.32 1.28 1.36 -1.33 -1.09
Sec61 translocon complex 8 -1.51 1.3 -1.14 -1.0 -1.28 -1.7 1.22
signal recognition particle receptor complex 4 -1.91 1.42 -1.08 1.06 -1.35 -1.79 1.42
signal recognition particle, endoplasmic reticulum targeting 9 -1.25 1.37 1.01 1.14 -1.09 -1.57 1.26
signal peptidase complex 3 1.12 -1.0 1.0 -1.02 -1.02 -1.01 1.75
smooth endoplasmic reticulum 5 2.12 -1.15 1.68 -1.13 1.04 1.12 1.23
rough endoplasmic reticulum 15 -1.44 1.23 -1.0 1.01 -1.26 -1.5 1.29
endoplasmic reticulum-Golgi intermediate compartment 1 -1.08 1.49 -1.64 1.02 -1.4 -2.11 -1.11
ER to Golgi transport vesicle 4 1.31 1.22 1.29 1.04 1.28 1.43 2.03
trans-Golgi network 6 -1.72 1.13 1.32 1.15 1.37 1.03 1.11
transport vesicle 15 1.23 1.06 1.2 -1.01 1.17 1.53 1.45
transport vesicle membrane 4 -1.16 1.25 1.59 1.05 1.44 1.76 1.54
actomyosin contractile ring 4 -1.06 1.15 1.51 1.14 1.77 1.47 1.16
polysome 1 2.2 1.38 1.27 1.25 1.7 1.45 1.27
mRNA cap binding complex 2 1.35 1.18 1.45 1.11 1.5 1.76 1.35
mRNA cleavage and polyadenylation specificity factor complex 7 1.3 1.31 1.42 1.47 1.64 1.34 1.15
eukaryotic translation initiation factor 3 complex 16 1.44 1.14 1.33 1.03 1.2 1.61 1.17
eukaryotic translation elongation factor 1 complex 5 2.72 -1.02 1.29 -1.13 1.23 1.37 1.32
nascent polypeptide-associated complex 3 1.55 -1.11 1.12 1.0 1.05 1.16 1.07
muscle myosin complex 5 4.08 -1.62 1.08 -1.52 1.03 2.86 -1.26
troponin complex 2 6.95 -2.33 -1.12 -1.86 1.08 3.33 -1.76
muscle thin filament tropomyosin 2 3.23 -1.38 1.31 -1.15 1.21 2.24 -1.26
striated muscle myosin thick filament 3 2.91 -1.49 1.05 -1.32 1.04 2.39 -1.29
striated muscle thin filament 5 3.24 -1.5 1.09 -1.38 1.25 2.3 -1.28
nuclear microtubule 1 1.51 1.15 1.47 1.1 1.35 1.02 -1.14
Arp2/3 protein complex 5 -3.04 -1.69 -1.35 1.45 1.29 -2.9 -1.36
sodium:potassium-exchanging ATPase complex 8 1.13 -1.11 1.22 -1.35 -1.0 1.53 1.06
insulin receptor complex 1 1.01 1.43 1.57 1.5 2.27 1.72 1.64
caveola 1 3.68 -1.06 -1.03 1.16 1.0 1.99 -1.04
microvillus 5 1.36 1.2 1.61 -1.02 1.17 1.09 1.29
brush border 3 -22.7 -1.04 -2.81 1.01 -1.94 1.91 -2.7
cell-cell junction 66 1.52 -1.07 1.19 -1.11 1.18 1.85 1.41
cell-cell adherens junction 13 1.51 1.27 1.67 1.06 1.61 1.75 1.74
spot adherens junction 4 1.12 1.24 1.44 1.07 1.52 1.53 1.48
zonula adherens 9 1.2 1.26 1.62 1.08 1.63 1.49 1.6
nephrocyte diaphragm 3 -3.44 1.01 1.01 1.15 1.01 -2.84 -1.29
septate junction 22 2.96 -1.28 1.21 -1.34 1.26 3.68 1.76
pleated septate junction 3 3.11 -1.4 1.27 -1.39 1.24 4.46 1.69
gap junction 8 -1.22 -1.27 -1.23 -1.25 -1.39 1.09 1.54
tight junction 4 1.14 1.05 1.46 1.03 1.1 1.55 1.04
connecting hemi-adherens junction 1 1.1 1.42 2.42 1.36 2.63 2.12 3.14
muscle tendon junction 5 2.04 -1.05 1.1 -1.07 -1.09 1.36 1.08
septin ring 5 -1.56 1.08 1.09 1.16 1.34 -1.29 1.06
phosphatidylinositol 3-kinase complex 4 -1.6 1.29 1.4 1.19 1.74 -1.12 -1.04
1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex 2 -1.54 1.47 1.35 1.15 1.83 1.07 1.48
6-phosphofructokinase complex 1 2.63 -1.22 -1.22 1.02 -1.12 5.11 1.3
mitochondrial alpha-ketoglutarate dehydrogenase complex 1 -1.4 -1.14 2.27 -1.25 -1.48 1.94 -1.5
cAMP-dependent protein kinase complex 6 1.3 1.06 1.3 -1.12 1.18 1.98 1.03
calcium- and calmodulin-dependent protein kinase complex 2 1.81 1.24 1.48 1.18 1.44 2.31 1.51
calcineurin complex 5 1.63 -1.01 1.24 1.04 1.14 1.3 1.06
DNA-dependent protein kinase-DNA ligase 4 complex 2 -1.03 1.29 1.58 1.29 1.51 -1.21 1.27
glycine cleavage complex 4 1.1 -1.07 1.31 -1.13 -1.08 2.33 -1.17
mitochondrial isocitrate dehydrogenase complex (NAD+) 1 -1.07 1.16 -1.05 -1.13 1.15 1.71 1.06
phosphorylase kinase complex 3 1.8 1.28 1.21 1.07 1.13 2.26 1.63
protein farnesyltransferase complex 1 -1.83 -1.28 -1.22 1.05 -1.01 -1.04 2.75
mitochondrial pyruvate dehydrogenase complex 1 1.23 1.19 1.96 -1.07 1.35 3.33 1.11
ribonucleoside-diphosphate reductase complex 2 -2.27 -1.06 1.44 1.36 1.87 -1.61 -1.54
polysaccharide metabolic process 131 -1.49 -1.56 -1.71 -1.43 -1.46 -1.36 1.27
glycogen metabolic process 9 2.15 1.01 -1.12 1.0 1.05 2.73 1.34
glycogen biosynthetic process 5 2.74 -1.19 -1.42 1.04 1.07 2.78 1.29
glycogen catabolic process 1 2.98 -1.08 1.5 -1.31 1.12 4.86 1.33
disaccharide metabolic process 5 2.21 -1.79 -2.13 -1.71 -1.22 2.7 -1.01
trehalose metabolic process 5 2.21 -1.79 -2.13 -1.71 -1.22 2.7 -1.01
trehalose biosynthetic process 3 3.57 -2.83 -2.37 -2.36 -1.16 5.45 -1.46
monosaccharide metabolic process 74 -1.39 -1.01 -1.54 1.02 -1.04 -1.38 -1.41
fructose metabolic process 1 1.09 -1.34 2.59 -1.04 1.14 3.38 -1.06
fructose 2,6-bisphosphate metabolic process 1 1.09 -1.34 2.59 -1.04 1.14 3.38 -1.06
fucose metabolic process 4 -1.24 1.16 -1.09 -1.11 1.15 -1.73 2.16
L-fucose biosynthetic process 2 -1.67 1.21 1.13 1.24 1.36 -1.89 -1.14
glucose catabolic process 33 1.52 1.06 -1.18 -1.03 -1.06 1.37 1.2
galactose metabolic process 1 -2.18 1.44 -1.11 -1.39 1.11 -2.6 2.04
mannose metabolic process 11 -9.63 -1.07 -4.72 1.44 -1.08 -9.35 -13.32
inositol metabolic process 2 2.7 -2.43 -2.03 -2.2 -1.38 3.25 -1.23
inositol biosynthetic process 1 1.86 -1.46 -1.12 -1.51 1.13 1.83 1.71
aminoglycan metabolic process 120 -1.64 -1.63 -1.78 -1.48 -1.53 -1.5 1.27
aminoglycan catabolic process 29 -1.22 -1.95 -2.17 -1.68 -1.71 -1.1 1.4
glycosaminoglycan catabolic process 12 -1.13 -1.64 -1.19 -1.04 -1.82 -1.69 -1.29
chitin metabolic process 96 -1.91 -1.76 -2.05 -1.64 -1.62 -1.64 1.34
chitin biosynthetic process 4 1.85 -1.21 -1.08 -1.24 -1.23 2.11 1.33
chitin catabolic process 17 -1.28 -2.2 -3.31 -2.38 -1.64 1.24 2.14
cuticle chitin metabolic process 7 -1.6 -1.5 -2.17 -1.7 -1.06 1.36 1.67
cuticle chitin biosynthetic process 3 1.16 -1.14 1.05 -1.21 -1.11 2.09 1.42
cuticle chitin catabolic process 4 -2.55 -1.85 -4.04 -2.19 -1.03 -1.02 1.9
ethanol metabolic process 2 1.95 -1.28 -2.91 -1.89 1.06 1.72 1.15
ethanol oxidation 2 1.95 -1.28 -2.91 -1.89 1.06 1.72 1.15
cellular glucan metabolic process 9 2.15 1.01 -1.12 1.0 1.05 2.73 1.34
cellular aldehyde metabolic process 8 1.58 -1.07 -1.41 -1.33 -1.03 1.21 1.04
acetyl-CoA biosynthetic process from pyruvate 1 1.23 1.19 1.96 -1.07 1.35 3.33 1.11
pyruvate metabolic process 10 1.06 1.22 1.23 -1.11 1.04 1.51 1.12
generation of precursor metabolites and energy 140 1.11 1.05 1.13 1.0 1.09 1.53 -1.12
gluconeogenesis 4 1.09 -1.28 -1.21 -1.39 1.08 1.63 -1.02
glyoxylate cycle 1 1.5 1.55 -1.65 -1.56 -1.01 -1.09 1.26
pentose-phosphate shunt 7 2.13 1.17 -1.85 1.03 -1.09 1.03 1.53
tricarboxylic acid cycle 36 -1.0 1.09 1.26 -1.05 1.07 1.52 -1.04
2-oxoglutarate metabolic process 2 -1.13 -1.34 1.15 -1.41 1.89 2.28 -2.14
fumarate metabolic process 6 -1.06 -1.08 1.01 -1.19 1.09 1.49 -1.51
isocitrate metabolic process 1 1.5 1.55 -1.65 -1.56 -1.01 -1.09 1.26
regulation of carbohydrate metabolic process 3 -1.56 -1.05 -1.43 -1.32 1.05 1.6 2.11
energy reserve metabolic process 9 2.15 1.01 -1.12 1.0 1.05 2.73 1.34
NADH oxidation 1 -1.32 -1.9 1.3 -2.14 3.35 4.87 -4.48
acetaldehyde metabolic process 2 2.78 -1.16 -2.38 -2.31 -1.44 1.4 1.22
respiratory electron transport chain 63 1.04 1.03 1.18 1.06 1.12 1.53 -1.32
oxidative phosphorylation 65 1.08 1.05 1.19 1.05 1.1 1.53 -1.32
mitochondrial electron transport, NADH to ubiquinone 31 1.15 1.03 1.29 1.07 1.13 1.74 -1.29
mitochondrial electron transport, succinate to ubiquinone 3 -1.1 1.07 1.36 -1.03 -1.0 1.57 -1.31
glycerophosphate shuttle 2 1.11 -1.19 -1.41 1.22 2.52 1.34 -1.21
glutathione metabolic process 4 -2.31 1.0 -1.94 1.16 1.13 -1.72 1.13
ADP biosynthetic process 2 -1.29 -1.01 -1.04 1.37 1.42 -2.05 -1.57
GMP biosynthetic process 2 1.15 1.21 1.23 -1.01 1.16 1.11 2.05
IMP biosynthetic process 7 1.14 1.03 -1.12 -1.04 -1.13 1.95 -1.01
'de novo' IMP biosynthetic process 6 1.13 1.02 -1.2 -1.03 -1.2 1.78 -1.03
'de novo' pyrimidine base biosynthetic process 6 1.66 -1.0 1.02 -1.03 -1.03 1.11 1.08
pyrimidine base catabolic process 3 2.92 -1.42 -1.24 -1.35 -1.35 1.45 1.16
cytidine catabolic process 3 -2.8 1.04 -1.39 1.2 1.32 -1.87 -1.06
dTDP biosynthetic process 1 1.27 1.13 1.91 1.21 1.41 -1.17 -1.08
DNA ligation 2 1.6 1.14 1.36 1.04 1.35 1.44 1.13
pre-replicative complex assembly 7 -1.21 1.08 1.17 1.27 1.62 -1.3 -1.19
DNA strand elongation involved in DNA replication 3 -1.21 -1.08 1.4 1.14 1.61 -1.08 -1.25
leading strand elongation 1 -1.9 -1.01 1.54 1.17 1.67 -2.38 -1.41
RNA-dependent DNA replication 1 1.54 1.82 1.92 -1.04 1.87 1.15 2.39
base-excision repair 6 1.51 -1.01 1.25 1.11 1.19 1.33 -1.13
nucleotide-excision repair, DNA incision, 5'-to lesion 1 1.98 1.16 1.33 1.18 1.39 1.07 1.02
DNA dealkylation involved in DNA repair 1 1.12 -1.01 1.19 1.74 1.2 1.06 -1.09
DNA catabolic process 9 1.71 -1.1 1.05 -1.12 1.18 1.29 1.41
DNA fragmentation involved in apoptotic nuclear change 3 1.86 1.09 1.48 1.14 1.43 1.6 1.67
DNA replication-independent nucleosome assembly 1 -1.49 1.47 -1.04 1.39 1.42 -1.65 -1.06
chromatin-mediated maintenance of transcription 8 1.92 1.19 1.53 1.04 1.43 1.72 1.45
chromatin silencing at telomere 2 1.51 1.1 1.54 1.1 1.65 2.14 1.15
regulation of transcription from RNA polymerase III promoter 5 1.56 1.19 1.46 1.24 1.48 1.38 1.12
mRNA polyadenylation 16 1.4 1.12 1.26 1.13 1.32 1.72 1.2
adenosine to inosine editing 1 1.13 1.14 1.55 1.01 1.4 2.0 1.26
tRNA splicing, via endonucleolytic cleavage and ligation 3 1.93 1.15 1.42 1.2 1.36 1.44 1.34
transcription from mitochondrial promoter 3 1.29 1.23 1.41 1.12 1.47 1.73 -1.1
snRNA export from nucleus 2 1.9 1.18 1.33 1.29 1.62 1.23 1.13
tRNA export from nucleus 1 1.48 1.1 1.33 1.32 1.54 -1.18 -1.04
translational termination 6 1.2 1.18 1.21 1.16 1.16 1.51 1.06
aspartyl-tRNA aminoacylation 1 -1.97 1.61 1.28 -1.18 1.45 -1.88 1.38
cysteinyl-tRNA aminoacylation 2 -1.01 1.37 1.43 1.08 1.22 1.24 1.76
glutamyl-tRNA aminoacylation 2 1.05 1.23 1.54 -1.01 1.6 1.42 1.27
histidyl-tRNA aminoacylation 1 -1.32 1.37 -1.07 1.31 -1.14 -1.74 -1.19
isoleucyl-tRNA aminoacylation 2 1.35 1.22 1.54 1.02 1.38 1.61 1.38
methionyl-tRNA aminoacylation 2 -1.59 1.18 1.28 1.38 1.17 -1.27 -1.03
threonyl-tRNA aminoacylation 2 -1.65 1.24 1.06 1.13 -1.08 -1.17 1.02
valyl-tRNA aminoacylation 2 -1.62 1.31 1.29 1.15 1.04 -1.25 1.17
regulation of translational initiation 10 1.76 -1.0 1.08 -1.04 1.23 1.53 1.27
regulation of translational initiation by iron 2 1.36 1.24 1.32 -1.06 1.1 1.69 1.16
regulation of translational elongation 3 1.5 1.19 1.07 1.08 1.04 1.01 1.17
regulation of translational termination 1 1.71 1.01 1.01 -1.13 1.21 1.32 1.15
translational readthrough 2 1.54 1.17 1.08 1.41 1.45 -1.1 -1.08
translational frameshifting 1 1.71 1.01 1.01 -1.13 1.21 1.32 1.15
signal peptide processing 3 1.12 -1.0 1.0 -1.02 -1.02 -1.01 1.75
negative regulation of protein kinase activity 12 1.53 1.14 1.46 1.09 1.41 1.69 1.32
N-terminal protein amino acid acetylation 1 -1.5 1.47 2.65 1.15 1.31 -1.14 -1.06
C-terminal protein methylation 1 -2.13 1.18 1.09 1.41 1.8 -1.71 -1.76
protein demethylation 7 1.18 1.25 1.72 1.13 1.59 1.68 1.3
protein N-linked glycosylation 14 1.33 1.02 1.11 1.03 1.13 1.55 1.26
N-glycan processing 1 3.13 1.28 1.73 1.05 1.33 2.12 2.37
N-terminal protein lipidation 2 -1.18 1.31 1.73 1.36 1.77 -1.01 -1.01
N-terminal protein myristoylation 1 -1.49 1.29 1.71 1.24 1.7 1.05 1.0
N-terminal protein palmitoylation 1 1.07 1.32 1.75 1.48 1.85 -1.07 -1.03
protein geranylgeranylation 1 1.07 1.22 1.65 1.13 1.53 -1.02 -1.05
proteolysis 624 -1.68 -1.23 -1.28 -1.03 -1.1 -1.65 -1.4
membrane protein ectodomain proteolysis 2 -1.1 1.22 1.43 1.31 1.8 -1.31 1.17
protein monoubiquitination 1 -1.01 -1.28 2.49 -1.24 1.59 -1.44 -1.52
misfolded or incompletely synthesized protein catabolic process 1 2.66 -1.19 -1.04 1.2 -1.17 1.37 1.41
glycoprotein catabolic process 1 -1.09 1.27 1.39 1.28 1.54 -1.1 1.18
protein deglycosylation 1 3.0 -1.25 -1.04 1.43 1.17 2.32 1.34
alanine metabolic process 1 1.7 1.2 1.13 1.08 -1.16 -1.08 1.29
alanine biosynthetic process 1 1.7 1.2 1.13 1.08 -1.16 -1.08 1.29
arginine metabolic process 5 -5.16 1.27 -5.44 1.2 1.07 -3.1 -1.21
arginine biosynthetic process 2 -22.15 1.64 -12.84 1.4 1.07 -7.77 -1.97
arginine catabolic process 2 -3.2 -1.06 -5.13 -1.12 -1.07 -1.58 1.05
aspartate metabolic process 2 1.83 1.18 -1.32 -1.0 1.19 1.57 1.14
cysteine metabolic process 3 1.38 1.11 1.22 -1.23 -2.05 -1.02 1.55
cysteine biosynthetic process from serine 1 1.25 1.1 1.48 -1.98 -7.11 -1.17 2.59
glutamate metabolic process 10 -1.06 -1.22 -1.57 -1.37 1.12 1.73 -1.05
glutamate biosynthetic process 5 1.59 -1.31 -1.43 -1.5 -1.34 2.96 1.23
glutamate catabolic process 4 -1.09 -1.24 1.09 -1.34 1.82 1.75 -1.68
glutamine metabolic process 5 -1.72 -1.12 -1.2 -1.13 1.54 -1.57 -3.03
glutamine biosynthetic process 2 1.91 -1.99 2.01 -1.44 1.52 -1.73 -1.25
glutamine catabolic process 1 -1.12 1.14 1.63 1.21 1.33 1.0 1.05
glycine metabolic process 9 1.41 1.01 1.25 -1.01 -1.01 1.77 -1.06
glycine biosynthetic process 1 2.25 -1.1 -1.03 1.28 1.09 2.14 -1.24
glycine catabolic process 6 1.21 1.07 1.39 -1.04 -1.02 1.86 -1.02
leucine metabolic process 4 1.15 1.54 1.31 1.24 1.31 1.45 1.1
lysine metabolic process 1 -1.51 -1.6 -1.42 1.8 -1.74 2.0 -2.55
lysine catabolic process 1 -1.51 -1.6 -1.42 1.8 -1.74 2.0 -2.55
methionine metabolic process 6 1.26 -1.05 -1.1 -1.03 -1.11 1.66 -1.23
S-adenosylmethionine biosynthetic process 1 1.6 1.05 1.23 -1.23 1.41 1.78 1.98
L-phenylalanine metabolic process 4 1.52 -1.14 -1.01 -1.01 -1.02 2.14 -1.13
L-phenylalanine catabolic process 4 1.52 -1.14 -1.01 -1.01 -1.02 2.14 -1.13
proline metabolic process 7 -1.43 -1.33 -1.79 -1.62 -1.41 1.63 1.05
proline biosynthetic process 4 -1.95 -1.03 -1.89 -1.37 -1.23 1.12 1.21
proline catabolic process 2 1.19 -2.55 -2.04 -2.77 -1.87 5.01 -1.07
L-serine metabolic process 5 2.33 1.11 -1.22 1.0 -1.34 1.61 1.43
L-serine biosynthetic process 4 2.73 1.12 -1.41 1.19 1.13 1.89 1.23
tryptophan catabolic process 2 1.18 -1.21 -1.17 -1.24 -1.21 1.62 -1.18
tyrosine metabolic process 8 1.53 -1.29 -1.23 -1.14 -1.34 1.56 1.15
betaine biosynthetic process 1 1.3 -1.08 -1.07 -1.13 -1.19 1.96 -1.06
ethanolamine metabolic process 1 1.07 -1.05 2.34 1.23 1.45 3.99 1.1
acetylcholine catabolic process 1 2.27 1.23 -5.17 -1.59 -2.2 -9.9 9.42
melanin metabolic process 16 2.27 -1.2 -1.16 -1.18 1.1 1.65 1.32
melanin biosynthetic process from tyrosine 4 1.82 -1.08 -1.09 -1.03 -1.18 1.82 -1.13
catecholamine metabolic process 9 -1.02 -1.18 -1.26 -1.16 -1.28 -1.1 1.52
dopamine biosynthetic process from tyrosine 1 1.23 -4.96 -5.74 -3.75 -6.41 -1.0 6.11
indolalkylamine metabolic process 8 -1.18 -1.2 -1.54 -1.13 -1.45 -1.17 1.22
serotonin biosynthetic process from tryptophan 2 1.67 -2.04 -2.31 -1.94 -2.17 1.48 3.91
activation of tryptophan 5-monooxygenase activity 1 2.28 1.19 1.07 -1.0 1.37 2.2 2.5
ornithine metabolic process 3 -2.2 1.14 -2.13 1.11 -1.02 -1.24 -1.28
polyamine biosynthetic process 5 1.03 -1.1 -1.08 1.04 -1.04 1.59 -1.28
spermine biosynthetic process 2 1.12 1.21 1.31 1.22 1.2 1.92 1.01
NLS-bearing substrate import into nucleus 7 -1.09 1.31 1.37 1.28 1.56 1.0 1.17
protein export from nucleus 5 1.19 1.11 2.28 1.15 1.72 1.71 1.32
cotranslational protein targeting to membrane 16 -1.27 1.37 -1.06 1.05 -1.21 -1.6 1.25
SRP-dependent cotranslational protein targeting to membrane 15 -1.21 1.37 -1.05 1.04 -1.19 -1.54 1.26
SRP-dependent cotranslational protein targeting to membrane, translocation 5 -1.62 1.28 -1.17 -1.01 -1.28 -1.9 1.13
SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 1 -1.09 1.62 1.41 1.12 1.35 1.19 1.81
protein retention in ER lumen 3 -1.9 1.28 -1.09 1.08 -1.19 -2.08 1.34
protein targeting to lysosome 3 1.19 1.18 1.82 1.21 1.4 1.29 1.24
protein targeting to vacuole 4 1.47 1.26 2.02 1.17 1.52 1.6 1.47
fatty acid biosynthetic process 25 1.1 -1.38 -1.52 -1.26 -1.29 1.04 1.14
fatty acid beta-oxidation 12 -1.2 1.1 -1.58 1.06 1.17 -2.29 -1.36
unsaturated fatty acid biosynthetic process 1 -1.74 1.11 -2.01 1.51 1.27 -1.87 -1.55
acyl-CoA metabolic process 6 2.01 1.03 1.27 1.12 1.42 1.33 1.06
neutral lipid metabolic process 10 1.74 -1.01 1.02 -1.04 1.58 -1.11 -1.1
acylglycerol metabolic process 10 1.74 -1.01 1.02 -1.04 1.58 -1.11 -1.1
triglyceride metabolic process 7 1.7 1.03 -1.06 -1.02 1.5 1.09 -1.06
triglyceride mobilization 1 -2.11 1.69 -1.72 -1.16 2.47 -2.75 -1.82
membrane lipid metabolic process 28 -2.18 -1.19 -1.19 1.18 1.02 -2.06 -1.41
phosphatidylethanolamine biosynthetic process 1 1.07 -1.05 2.34 1.23 1.45 3.99 1.1
diacylglycerol biosynthetic process 2 4.42 -1.06 2.12 -1.4 1.56 1.46 1.74
phosphatidylglycerol biosynthetic process 1 -3.36 1.4 1.32 1.25 1.35 -2.25 1.21
phosphatidylcholine biosynthetic process 1 -1.0 -1.38 1.09 1.05 1.26 -1.4 2.06
phosphatidylserine metabolic process 1 1.61 1.37 2.22 1.0 1.13 1.67 1.83
phosphatidylserine biosynthetic process 1 1.61 1.37 2.22 1.0 1.13 1.67 1.83
glycolipid metabolic process 8 1.02 1.23 1.09 1.02 1.05 -1.13 1.74
sphingolipid metabolic process 24 -2.32 -1.33 -1.28 1.19 1.03 -2.16 -1.6
ceramide metabolic process 7 -1.82 -1.06 1.22 1.15 1.12 -2.11 -1.7
sphingomyelin metabolic process 5 -5.26 -3.33 -4.18 1.39 -1.08 -3.6 -4.11
sphingomyelin catabolic process 3 -14.19 -8.88 -14.23 1.69 -1.38 -9.59 -10.93
sphingomyelin biosynthetic process 1 -1.01 1.47 1.74 -1.23 1.22 1.11 1.04
glycosphingolipid metabolic process 5 1.35 1.03 1.0 1.01 1.04 1.17 1.95
glycosphingolipid biosynthetic process 4 1.47 1.01 -1.03 -1.08 1.02 1.2 2.34
icosanoid metabolic process 1 -1.74 1.11 -2.01 1.51 1.27 -1.87 -1.55
leukotriene metabolic process 1 -1.74 1.11 -2.01 1.51 1.27 -1.87 -1.55
cholesterol biosynthetic process 1 2.16 -1.1 1.03 -1.13 1.06 2.2 1.18
cholesterol catabolic process 1 -1.19 1.24 1.2 1.43 1.53 -1.12 -1.13
sesquiterpenoid metabolic process 6 -1.16 -1.26 -1.56 -1.5 -1.43 -2.35 1.61
juvenile hormone metabolic process 6 -1.16 -1.26 -1.56 -1.5 -1.43 -2.35 1.61
juvenile hormone biosynthetic process 2 1.77 -2.92 -3.1 -3.09 -1.69 -1.43 2.62
juvenile hormone catabolic process 4 -1.67 1.21 -1.1 -1.05 -1.31 -3.02 1.26
terpenoid metabolic process 11 -1.32 -1.26 -1.61 -1.13 -1.21 -1.86 1.01
pteridine biosynthetic process 5 2.4 -1.22 -1.26 -1.24 -1.16 -1.04 1.7
tetrahydrobiopterin biosynthetic process 4 7.84 -1.48 -1.41 -1.58 -1.23 1.76 2.48
one-carbon metabolic process 15 -1.73 -1.28 1.21 -1.29 1.06 1.32 -1.1
oxidoreduction coenzyme metabolic process 16 1.6 1.17 -1.26 1.03 1.09 1.19 1.2
NADH metabolic process 1 -1.32 -1.9 1.3 -2.14 3.35 4.87 -4.48
NADP metabolic process 7 2.13 1.17 -1.85 1.03 -1.09 1.03 1.53
NADPH regeneration 7 2.13 1.17 -1.85 1.03 -1.09 1.03 1.53
lipoamide metabolic process 1 -1.4 -1.14 2.27 -1.25 -1.48 1.94 -1.5
glutathione biosynthetic process 3 -2.99 1.44 -1.36 1.22 -1.32 -2.2 1.15
ATP biosynthetic process 25 1.34 1.04 1.24 -1.05 1.09 1.66 -1.1
folic acid-containing compound metabolic process 8 1.68 -1.27 -1.29 -1.11 -1.33 1.27 1.0
vitamin metabolic process 11 1.53 1.22 -1.23 -1.04 -1.18 1.35 1.13
water-soluble vitamin metabolic process 7 1.81 1.34 -1.5 -1.06 -1.3 1.43 1.2
riboflavin metabolic process 2 1.78 2.05 -2.11 -2.16 -2.52 2.14 1.44
thiamine metabolic process 1 1.06 1.62 -1.26 1.22 -1.14 -1.11 1.12
protoporphyrinogen IX biosynthetic process 1 1.62 1.26 1.09 -1.07 1.01 1.21 1.32
heme a biosynthetic process 1 -1.08 1.29 1.99 1.12 1.3 1.57 -1.3
porphyrin-containing compound catabolic process 1 2.0 1.05 2.09 1.06 1.46 2.34 1.12
heme oxidation 1 2.0 1.05 2.09 1.06 1.46 2.34 1.12
xenobiotic metabolic process 10 1.1 -1.02 -1.79 -1.06 -1.28 -1.46 1.06
response to insecticide 16 1.05 1.09 -1.54 -1.14 -1.27 -1.41 1.29
calcium ion transport 24 1.54 -1.04 1.07 -1.11 1.19 1.63 1.19
phosphate ion transport 10 -1.16 -1.04 -1.52 -1.15 1.01 2.17 -1.68
chloride transport 6 1.12 1.13 -1.09 1.06 1.34 1.82 1.32
water transport 3 -1.65 1.03 -1.57 1.34 -1.36 -2.48 1.11
dicarboxylic acid transport 8 1.09 -1.04 -1.41 -1.66 -1.35 1.44 1.09
serotonin transport 1 -1.06 -1.11 -1.0 -1.08 -1.15 3.37 -1.04
alpha-ketoglutarate transport 3 -1.11 -1.06 1.14 -1.03 -1.15 1.61 -1.21
malate transport 5 -1.06 -1.22 1.26 -1.12 1.12 2.23 -1.26
mitochondrial citrate transport 1 -1.29 1.86 -1.38 -1.29 -2.25 1.02 -1.13
acyl carnitine transport 2 1.34 1.32 -1.91 1.22 1.14 -1.7 -1.23
aspartate transport 1 2.24 1.81 -38.59 -31.15 -18.58 -3.21 4.55
L-glutamate transport 4 -2.92 -1.1 -4.98 -1.98 -1.32 -2.35 -3.75
mitochondrial calcium ion transport 1 1.01 1.3 1.51 1.08 2.35 4.41 1.77
drug transmembrane transport 1 -10.37 1.6 -11.08 1.04 2.2 -3.48 1.28
oligopeptide transport 3 1.69 -1.17 -1.51 -1.15 -1.07 1.17 1.2
amino acid transport 39 -1.51 -1.14 -1.83 -1.24 1.0 -1.08 -1.16
glutamine transport 1 -3.47 -4.26 1.06 2.44 2.17 -3.37 -7.09
lipid transport 28 -2.26 -1.6 -1.93 -1.01 -1.22 -1.56 -1.89
cellular calcium ion homeostasis 10 1.86 -1.02 1.36 -1.1 -1.04 1.64 1.18
cellular copper ion homeostasis 2 -1.26 1.35 2.1 1.13 1.14 1.39 1.07
cellular zinc ion homeostasis 1 -1.15 1.5 3.36 1.09 -1.02 -1.02 -1.03
cell volume homeostasis 2 1.92 1.08 -1.06 -1.08 2.11 2.25 1.09
regulation of pH 9 -1.27 1.25 1.91 -1.01 1.19 1.86 1.45
retrograde vesicle-mediated transport, Golgi to ER 8 -1.71 1.25 -1.07 1.15 -1.15 -1.33 1.34
intra-Golgi vesicle-mediated transport 18 -1.13 1.2 1.21 1.08 1.18 1.32 1.58
Golgi to vacuole transport 1 1.54 1.27 1.89 1.07 1.6 1.7 1.58
receptor-mediated endocytosis 11 1.09 1.13 1.29 1.01 1.19 1.55 1.26
anti-apoptosis 18 1.77 1.02 1.32 -1.0 1.46 1.51 1.52
cellular component disassembly involved in apoptotic process 4 -1.16 1.19 1.65 1.21 1.51 -1.05 -1.11
cleavage of lamin 1 -11.86 1.52 2.29 1.45 1.79 -4.95 -7.15
cleavage of cytoskeletal proteins involved in apoptosis 1 -11.86 1.52 2.29 1.45 1.79 -4.95 -7.15
regulation of muscle contraction 5 2.39 -1.02 -2.05 -2.54 -2.17 1.16 1.24
striated muscle contraction 4 -1.17 -1.12 -1.49 -1.32 -1.09 1.16 1.78
regulation of striated muscle contraction 2 1.48 1.35 -6.16 -5.66 -4.42 -1.74 2.14
response to mechanical stimulus 14 1.05 -1.27 1.01 -1.36 -1.07 1.88 1.17
pattern orientation 1 1.15 1.52 1.62 1.11 1.74 1.53 2.02
positive regulation of antibacterial peptide biosynthetic process 17 1.54 -1.16 -1.04 -1.14 1.02 1.29 1.37
positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria 5 2.54 -1.22 -1.03 -1.31 -1.06 2.04 1.48
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria 4 1.05 -1.9 -2.24 -1.85 -1.9 -1.18 1.68
positive regulation of antifungal peptide biosynthetic process 6 2.45 -1.42 -1.16 -1.01 -1.05 1.77 1.2
cellular defense response 1 1.57 1.3 1.87 1.1 1.6 2.04 2.1
hyperosmotic response 1 1.22 1.33 2.18 1.07 1.72 2.05 1.61
response to lipid hydroperoxide 1 2.0 -1.09 -1.07 1.14 1.47 1.02 -1.28
ER overload response 2 -1.22 1.43 1.56 1.09 1.42 -1.17 1.79
nuclear pore organization 1 1.8 1.61 2.39 1.2 2.33 2.16 2.46
nucleolus organization 3 1.16 1.19 1.66 1.24 2.3 1.1 1.42
plasma membrane organization 12 1.23 1.13 1.5 1.02 1.84 1.37 1.27
cytoskeletal anchoring at plasma membrane 17 1.37 1.1 1.43 1.03 1.41 1.51 1.32
microtubule nucleation 7 1.67 1.03 1.42 1.09 1.45 1.62 1.17
negative regulation of microtubule depolymerization 15 1.06 1.15 1.48 1.04 1.41 1.59 1.26
endoplasmic reticulum organization 7 1.12 1.24 1.29 1.1 1.28 1.04 1.52
peroxisome organization 15 1.58 1.07 -1.39 1.25 1.36 -1.44 -1.19
vacuolar transport 17 1.14 1.17 1.78 1.13 1.5 1.47 1.29
vacuolar acidification 4 -2.16 1.36 2.14 -1.07 1.21 2.24 1.25
lysosomal transport 13 -1.01 1.15 1.71 1.13 1.47 1.31 1.22
cell-cell junction assembly 36 1.91 -1.1 1.31 -1.15 1.22 2.16 1.42
cell-substrate junction assembly 1 -1.1 -1.15 -1.07 -1.18 1.52 1.28 1.24
cell cycle arrest 8 1.45 1.2 1.34 1.1 1.36 1.5 1.38
spindle assembly involved in male meiosis 3 -1.71 1.36 1.08 1.16 1.08 -1.71 1.01
spindle assembly involved in male meiosis I 1 1.11 1.51 1.01 1.21 1.06 -1.41 1.26
mitotic sister chromatid cohesion 5 1.6 1.06 1.64 1.1 1.59 1.67 1.28
regulation of S phase of mitotic cell cycle 16 1.38 1.18 1.34 1.13 1.4 1.63 1.43
optokinetic behavior 2 1.16 1.09 1.72 1.19 1.37 1.2 2.11
cytokinesis after meiosis I 8 1.52 -1.23 1.02 -1.47 1.08 1.67 1.38
cytokinesis after meiosis II 7 1.71 -1.31 -1.08 -1.6 1.08 2.04 1.46
male meiosis cytokinesis 14 1.82 -1.04 1.11 -1.11 1.39 1.32 1.33
meiotic prophase I 1 1.5 1.02 1.68 -1.05 1.78 1.86 1.49
meiotic metaphase I 1 1.38 1.21 1.33 1.18 1.64 1.12 1.06
homophilic cell adhesion 27 1.7 -1.16 -1.1 -1.17 1.12 1.92 1.39
negative regulation of cell adhesion 9 1.95 1.17 1.32 1.03 1.28 1.88 1.51
signal complex assembly 1 1.01 1.19 1.87 1.24 1.92 1.43 1.32
transforming growth factor beta binding 1 -2.53 1.23 -1.01 1.28 2.46 1.22 1.76
transforming growth factor beta receptor complex assembly 1 -2.53 1.23 -1.01 1.28 2.46 1.22 1.76
transmembrane receptor protein tyrosine phosphatase signaling pathway 1 1.65 1.02 2.09 -1.05 1.83 4.08 1.95
elevation of cytosolic calcium ion concentration 3 1.46 1.16 1.52 -1.0 1.18 1.77 1.54
activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway 8 1.65 1.05 -1.03 -1.02 -1.04 1.17 1.24
tachykinin receptor signaling pathway 5 -1.04 -1.19 1.08 -1.24 -1.02 1.95 1.43
neuropeptide signaling pathway 38 -1.86 -1.39 -1.2 -1.15 -1.16 -1.83 -1.26
Notch receptor processing 4 -1.0 1.17 1.21 1.25 1.56 1.22 1.41
patched ligand maturation 1 1.07 1.32 1.75 1.48 1.85 -1.07 -1.03
signal transduction downstream of smoothened 5 1.03 1.18 1.56 1.12 1.42 1.4 1.07
positive regulation of hh target transcription factor activity 5 1.03 1.18 1.56 1.12 1.42 1.4 1.07
integrin-mediated signaling pathway 4 -1.54 1.07 1.65 1.1 1.77 -1.22 1.11
I-kappaB kinase/NF-kappaB cascade 2 1.26 1.28 1.33 1.08 1.48 1.61 1.39
JNK cascade 25 1.0 1.14 1.47 1.1 1.5 1.24 1.42
activation of JNKK activity 2 1.23 1.27 1.56 1.2 1.54 1.23 1.3
activation of JUN kinase activity 2 -1.08 1.31 1.72 1.2 1.5 1.32 1.54
tyrosine phosphorylation of STAT protein 1 1.57 1.3 1.87 1.1 1.6 2.04 2.1
STAT protein import into nucleus 1 1.57 1.3 1.87 1.1 1.6 2.04 2.1
Ras protein signal transduction 25 1.08 1.28 1.57 1.08 1.47 1.22 1.49
Rho protein signal transduction 4 -1.15 1.27 1.54 1.2 1.45 1.01 1.39
neuron-neuron synaptic transmission 5 1.1 -1.05 -1.09 -1.15 1.01 2.0 1.04
synaptic transmission, cholinergic 1 2.27 1.23 -5.17 -1.59 -2.2 -9.9 9.42
ensheathment of neurons 6 1.77 -1.07 1.38 -1.13 1.24 3.0 1.46
pole cell fate determination 3 2.8 1.18 2.04 1.19 1.51 2.12 1.41
primary spermatocyte growth 5 2.0 1.25 1.67 1.27 1.92 1.51 1.27
growth of a germarium-derived egg chamber 5 1.5 1.13 1.67 1.04 1.5 1.59 1.41
vitellogenesis 7 1.4 -3.65 -4.11 -4.07 -1.34 2.21 1.12
ovarian follicle cell-cell adhesion 3 -1.5 1.41 1.37 1.22 1.72 -1.12 -1.09
nurse cell nucleus anchoring 1 -1.33 1.57 2.09 1.17 1.77 1.11 1.58
eggshell chorion gene amplification 17 1.11 1.21 1.43 1.19 1.52 1.14 1.14
oocyte dorsal/ventral axis specification 34 1.43 1.04 1.13 1.01 1.1 1.5 1.28
maternal specification of dorsal/ventral axis, oocyte, germ-line encoded 7 1.96 -1.07 -1.01 -1.08 1.03 2.21 1.39
pole plasm protein localization 10 1.29 1.15 1.44 1.11 1.37 1.64 1.23
negative regulation of oskar mRNA translation 8 1.19 -1.01 1.28 -1.09 1.13 1.88 1.01
regulation of preblastoderm mitotic cell cycle 1 2.87 1.19 1.15 1.16 1.39 3.16 1.43
zygotic specification of dorsal/ventral axis 5 1.69 1.14 1.51 1.04 1.21 1.21 1.19
zygotic determination of anterior/posterior axis, embryo 31 1.57 -1.1 1.04 -1.14 1.04 1.27 1.27
anterior region determination 3 1.62 -1.05 1.0 -1.14 -1.1 1.06 -1.02
posterior abdomen determination 1 2.58 1.01 1.0 1.14 -1.0 -1.14 1.0
determination of left/right symmetry 4 -3.48 1.34 1.25 1.01 1.41 -1.67 1.12
ventral furrow formation 13 1.35 1.11 1.28 1.08 1.5 1.38 1.28
posterior midgut invagination 4 1.75 1.13 1.9 1.13 1.88 1.93 1.72
anterior midgut invagination 3 1.4 1.11 1.46 1.17 1.72 1.88 1.31
germ-band extension 8 -1.08 -1.25 1.17 1.08 1.55 1.32 -1.22
amnioserosa formation 5 1.56 -1.06 1.14 -1.19 -1.08 -1.04 1.05
specification of segmental identity, antennal segment 3 1.59 -1.13 1.32 1.09 -1.18 -1.05 -1.16
specification of segmental identity, thorax 2 1.34 1.12 1.12 1.65 -1.14 1.05 -1.1
germ-band shortening 18 1.2 1.11 1.38 1.07 1.46 1.23 1.55
initiation of dorsal closure 17 1.16 1.17 1.59 1.07 1.56 1.2 1.36
dorsal closure, leading edge cell fate determination 3 1.0 1.08 1.89 1.0 1.21 -1.44 -1.04
dorsal closure, elongation of leading edge cells 12 1.22 1.22 1.4 1.12 1.59 1.38 1.41
dorsal closure, spreading of leading edge cells 4 1.03 1.07 2.59 -1.02 1.79 1.38 1.66
suture of dorsal opening 3 -1.66 1.12 1.92 -1.03 1.4 -1.35 1.31
glial cell fate determination 3 1.44 1.3 1.68 1.12 1.63 1.5 1.59
negative regulation of neuroblast proliferation 7 -1.32 1.13 1.47 1.06 1.79 1.22 1.08
stomatogastric nervous system development 3 1.52 1.02 1.2 1.12 1.56 1.54 1.47
open tracheal system development 179 1.41 1.03 1.26 -1.02 1.26 1.52 1.28
epithelial cell fate determination, open tracheal system 5 1.83 1.1 1.52 -1.02 1.42 1.21 1.34
epithelial cell migration, open tracheal system 28 1.66 -1.03 1.29 -1.07 1.21 1.38 1.11
primary branching, open tracheal system 14 1.41 1.06 1.72 1.04 1.34 1.6 1.2
secondary branching, open tracheal system 4 -1.26 1.18 1.54 -1.02 1.25 1.45 1.01
terminal branching, open tracheal system 10 1.25 1.17 1.56 1.07 1.46 1.37 1.13
salivary gland boundary specification 12 1.24 1.02 1.3 1.14 1.55 1.11 1.19
larval salivary gland morphogenesis 6 -1.03 1.12 1.25 1.04 1.36 1.52 1.57
ectodermal digestive tract development 5 1.46 1.11 -1.0 1.02 1.62 1.8 1.33
dorsal/ventral lineage restriction, imaginal disc 7 1.04 1.11 1.08 1.07 1.41 1.38 1.52
progression of morphogenetic furrow involved in compound eye morphogenesis 8 1.62 -1.01 1.33 1.05 1.35 1.15 1.12
regulation of rhodopsin gene expression 2 1.63 1.26 1.37 1.04 1.38 1.48 1.42
wing disc proximal/distal pattern formation 6 1.82 -1.07 1.3 1.34 1.32 1.02 -1.06
apposition of dorsal and ventral imaginal disc-derived wing surfaces 17 1.92 1.04 1.15 -1.07 1.24 1.93 1.28
haltere disc morphogenesis 2 2.21 -1.24 1.11 1.19 -1.26 -1.2 -1.1
imaginal disc-derived genitalia development 22 1.56 1.05 1.18 1.02 1.13 1.11 1.24
imaginal disc-derived male genitalia development 20 1.63 1.05 1.2 1.02 1.16 1.13 1.28
analia development 6 -1.15 -1.64 -1.26 1.2 1.4 -1.24 -1.79
histoblast morphogenesis 8 -1.19 1.09 1.37 1.16 1.65 -1.2 1.21
maintenance of imaginal histoblast diploidy 1 -10.7 -1.04 2.18 1.33 2.43 -8.45 -1.16
endodermal cell fate determination 1 8.12 -1.58 1.44 -1.54 1.01 1.69 1.21
anterior midgut development 3 -1.08 1.25 1.25 -1.4 1.12 1.13 1.58
mesodermal cell fate determination 5 1.66 1.11 1.13 -1.01 1.25 1.53 1.29
larval heart development 2 1.04 -1.11 1.46 -1.3 -1.07 -1.65 1.78
mesoderm migration involved in gastrulation 10 1.62 -1.05 1.42 -1.16 1.22 2.32 1.08
hemocyte development 5 1.5 1.11 1.52 1.05 1.28 1.12 1.43
larval visceral muscle development 5 1.28 -1.03 1.19 -1.12 1.18 1.12 1.5
larval somatic muscle development 8 1.66 1.08 1.35 1.03 1.17 1.3 1.22
adult somatic muscle development 10 1.25 1.07 1.59 1.07 1.35 1.16 1.08
primary sex determination, germ-line 4 1.82 1.02 1.1 1.07 1.07 1.73 1.13
regulation of ecdysteroid metabolic process 1 -1.55 1.2 1.21 -1.19 -1.12 1.05 1.03
regulation of ecdysteroid secretion 1 -1.14 1.41 1.3 1.24 1.17 1.85 1.43
regulation of juvenile hormone metabolic process 2 -8.29 -1.83 1.21 1.4 1.08 -7.35 -3.84
regulation of juvenile hormone biosynthetic process 2 -8.29